Mucinex D and Anxiety: What Users Say (Page 2)

• Anonymous
• Taken for less than 1 month
• October 26, 2018

For Cough and Nasal Congestion "I have an insanely bad cold, and my sinuses are so stopped up. I took this thinking it would bring me some relief. It sure did, along with anxiety and feeling like I was cracked out of my mind!!!! Now I’m sitting here at 12 AM reading everyone else’s reviews when I have to go back to work tomorrow after 2 days off...ugh. No one told me the pseudoephedrine would make me so wired!"

• all...
• March 10, 2015

For Cough and Nasal Congestion "I’ve been coughing for days (unable to sleep because of the cough), can’t breathe through my nose and have a congestion headache. Took 2 pills in the morning, and it took a while to kick in, but several hours later I realized I could actually take a full breath through my nose, the headache improved, still coughing but not quite as bad. I didn’t have any issues with feeling jittery or wide awake."

• Hin...
• Taken for less than 1 month
• November 20, 2019

For Cough and Nasal Congestion "Do not take this at all unless you want to be up and feeling like you are never, ever going to sleep again. I was taking DayQuil until my very smart girlfriend offered me a Mucinex in the middle of the night. Never, ever take this or any other med containing pseudoephedrine. Whatever you are going through is not worth the anxiety and insomnia. I also threw up as well, which tasted exactly like the Mucinex."

• Mik...
• Taken for less than 1 month
• June 30, 2017

For Cough and Nasal Congestion "Had congestion for 3 weeks. Doctor gave me antibiotics and suggested Mucinex D twice a day. The first two days seemed to help congestion somewhat, but I had no appetite and was somewhat anxious. The third night, I took it at 11 p.m. and slept about 2 hours. Woke up with my heart racing and anxiety. I couldn't sleep and was pacing. Effects started to wear off at 10 a.m. Wish I had seen this site first."

• Mik...
• Taken for less than 1 month
• June 30, 2017

For Cough and Nasal Congestion "Had congestion for 3 weeks. Doctor gave me antibiotics and suggested Mucinex D twice a day. The first two days seemed to help congestion somewhat, but I had no appetite and was somewhat anxious. The third night, I took it at 11 p.m. and slept about 2 hours. Woke up with my heart racing and anxiety. I couldn't sleep and was pacing. Effects started to wear off at 10 a.m. Wish I had seen this site first."

• Mom...
• March 17, 2017

For Cough and Nasal Congestion "Followed directions & took 2x Mucinex D 1200mg at 9:30 PM. Decided to pick this up after being sick & out of work for 5 days. I was really tired & dozed off at 11:30 PM. It's 3:30 AM, I can't sleep... I'm wide awake with an extra dry mouth, swelling of the tongue, slight nausea, tossing & turning (anxiety?), tingling/weakness in my arms. Most of my cold symptoms are gone (amazingly!), but I can't shake these side effects right now & am wondering exactly when I'll be able to sleep! I would NOT recommend taking this at nighttime, & if you are going to try this stuff to start with just 1 pill."

• Dia...
• Taken for less than 1 month
• February 7, 2015

For Cough and Nasal Congestion "Took DM at bedtime and will never do that again! Yes, I felt better and felt some relief, however, the heart palpitations were out of this world! I was so jittery still 3 hours later that I literally couldn't sit still in my bed. Finally, I was able to sleep at 3 and woke up feeling super dehydrated and almost hungover, with puffy eyes and a bad headache. No más!"

• sic...
• Taken for less than 1 month
• November 4, 2016

For Cough and Nasal Congestion "Took this about three days into a pretty bad cold to relieve congestion, especially in my sinuses. Worked a charm! Took the adult dose around noon that day. Didn't have the same jittery side effects some are reporting and was, thankfully, able to take a nap that afternoon with the sinus relief it provided. My mom, on the other hand, says she can't take it after noon or else she won't sleep all night, so I understand your pain. All in all, worked great for me, but I understand that some people (for whatever reason) might have trouble sleeping if taken too late in the day."

• sle...
• Taken for less than 1 month
• September 23, 2019

For Cough and Nasal Congestion "I agree with so many that have left a review here! I do feel it helps with my cough and congestion, but I agree with the feeling of anxiety, heart racing, and most definitely sleepless nights (which is due to the pseudoephedrine in it)! I need my sleep. I may just take it in the AM or just not take it anymore. Not to mention it is very expensive for OTC (behind the pharmacy) medicine. My prescriptions with my insurance are way less than this!"

• Sic...
• Taken for less than 1 month
• December 7, 2022

For Cough and Nasal Congestion "I will never take this again, ever. While it did clear my sinuses and gave me that kind of relief, it kept me up all night long, and not just insomnia, but feelings of anxiety as well. I wouldn't even risk taking this during the day, so severe were the side effects. I'm going to stick to my Alka-Seltzer Cold and Flu and my NyQuil. Seriously, do not take this."

• Anonymous
• October 14, 2009

For Cough and Nasal Congestion "This worked on my sinuses, however, my heart rate increases so much that I feel jittery. The insomnia is a setback. The relief is great, but I'm not sure the things that go with it are worth it. Although my heart rate being up made me lose weight."

• Can...
• March 16, 2019

For Cough and Nasal Congestion "I took this for some relief of nasal and chest congestion. Let me warn you, do not take it, as within a half hour my heart was racing and I was jittery and anxious. On top of it, it made me sick to my stomach and I feel like someone is sitting on my chest. I can’t quench my thirst, no matter how much water I drink. I hope this feeling doesn’t last the entire 12 hours. This is horrible. I will never take this again, and this should be removed from the market."

• Can...
• March 16, 2019

For Cough and Nasal Congestion "I took this for some relief of nasal and chest congestion. Let me warn you, do not take it, as within a half hour my heart was racing and I was jittery and anxious. On top of it, it made me sick to my stomach and I feel like someone is sitting on my chest. I can’t quench my thirst, no matter how much water I drink. I hope this feeling doesn’t last the entire 12 hours. This is horrible. I will never take this again, and this should be removed from the market."

• Anonymous
• February 25, 2011

For Cough and Nasal Congestion "When I took Mucinex D maximum strength for the first time, I did have great relief of congestion, but I also experienced a very scary rapid heartbeat, dizziness, and anxiety. The anxiety may be due to feeling like I had something really wrong going on, I'm not sure. I have taken many different OTC medications through the years and have never had an experience like this one."

• IAa...
• February 2, 2018

For Cough and Nasal Congestion "I was starting to feel like a head and sinus condition was coming on, and with our tropical vacay coming up in 10 days, I for sure wanted to kick it in the butt. Well, I took my first dose this evening at 9 pm, went to bed because of an early work schedule, and slept soundly till 11:30 pm. It is now 2:30 am, and I have experienced a rapid heartbeat, nausea, and jitteriness. I laid there for 2 hours thinking I could go back to sleep, and here I am. Kinda wished the pharmacist would have given me a heads-up. Now this is kickin' me in the butt!"

• Anonymous
• November 15, 2011

For Cough and Nasal Congestion "As far as getting rid of your cough goes, this medicine is awesome. I took 2 pills 2 nights ago, didn't sleep at all the first night, and have been jittery ever since. I drink a lot of tea, so I'm sure the caffeine is adding to it. I think next time I will take one and lay off the beverages with caffeine."

• Anonymous
• Taken for less than 1 month
• January 28, 2018

For Cough and Nasal Congestion "This is my second day taking Mucinex for a bad cold. It’s not worth it! It has cleared my nose and throat completely, but I cannot get any sleep! Which is the pseudoephedrine side effect. I feel more miserable not being able to sleep than I did with the cold! On top of that, my heart has been racing for hours, and I started to get very anxious and nervous. I took this yesterday at 6 pm, it’s now 3 am, and I’m wide awake. Never again!"

• Anonymous
• Taken for less than 1 month
• January 28, 2018

For Cough and Nasal Congestion "This is my second day taking Mucinex for a bad cold. It’s not worth it! It has cleared my nose and throat completely, but I cannot get any sleep! Which is the pseudoephedrine side effect. I feel more miserable not being able to sleep than I did with the cold! On top of that, my heart has been racing for hours, and I started to get very anxious and nervous. I took this yesterday at 6 pm, it’s now 3 am, and I’m wide awake. Never again!"

• Jul...
• January 22, 2018

For Cough and Nasal Congestion "I took it at about 5 pm today when my cough was getting worse. It is now 5:30 am, and I haven't slept one bit. I am so jittery, nauseous, and dizzy. My heart is racing, and my whole body is shaking. My cough is significantly better, but the fact that I will not be getting sleep tonight for even a minute is quite the turn-off. I will never take this drug again."

• SSF...
• Taken for less than 1 month
• February 20, 2025

For Cough and Nasal Congestion "I highly recommend Mucinex D. First of all, I am not tolerant of many cold/allergy medicines. I was prescribed Mucinex D (2 pills every 12 hours) for my chest and nasal congestion. It seems everything I take affects me with anxiety, drowsiness, dry mouth, nausea, or something. So, to be safe, I took only 1 tablet to start. Within 1/2 hour, my cold symptoms were so much better, and I had no side effects from the pill. Then, 6 hours later, my cold symptoms started getting bad again. So, I took 1 more at 6 hours. Long story short, I have been taking Mucinex D for 3 days. But my schedule is 1 tablet every 6 hours, instead of 2 every 12 hours (still at the limit of 4 in 24 hours). I have had no trouble sleeping (except for the cough and nasal stuff). I am not sleepy, or anxious, or anything. In fact, I feel great. It does seem to be an appetite suppressant too...bonus! I am so glad I took the chance of making my own dosing schedule. It works!"

• Moa...
• April 10, 2021

For Cough and Nasal Congestion "I took this for two nights in a row because I couldn’t sleep. It did put me to sleep, but now the next night I got 3 hours of sleep because of anxiety, and I never have a problem sleeping. I will not be taking this again."

• jdk...
• Taken for less than 1 month
• September 22, 2014

For Cough and Nasal Congestion "I got the generic of Mucinex DM. It has definitely cut down the congestion and the coughing, which is great, but it's made me extremely jittery. I hope this feeling wears off soon."

• Moi...
• January 10, 2015

For Cough and Nasal Congestion "Helped somewhat with congestion, but I could not continue to take it due to insomnia (even after taking it during the day), jitters, dizziness, and anxiety."

• up ...
• March 18, 2014

For Cough and Nasal Congestion "Jittery and wide awake. But works great. Do not take before bed!"

• Kd0...
• Taken for less than 1 month
• May 6, 2013

For Cough and Nasal Congestion "Very effective at relieving symptoms, but my husband and I both are experiencing insomnia and some anxiety with it."