Guaifenesin / pseudoephedrine User Reviews & Ratings (Page 4)

• Zan...
• Taken for less than 1 month
• August 27, 2013

For Cough and Nasal Congestion "Absolutely amazing! My partner and I have nasal congestion for weeks, but 10 minutes after taking one, we coughed and all of a sudden were clear! I feel like I haven't used the bottom half of my lungs in weeks. A little bit expensive."

• Tha...
• October 10, 2018

For Cough and Nasal Congestion "I took Mucinex D last night because of slight congestion. It’s currently 4 a.m., and I have the PSAT in 4 hours. I’m wide awake, with my heart pounding and ears rushing. Thought it was the worst case of test-taking anxiety I’ve had, but alas, it was the Mucinex (the pseudoephedrine part). I do NOT recommend this for night use."

• Shi...
• August 20, 2009

For Cough and Nasal Congestion "For years, I had earaches and dizziness. Doctors told me that the drainage in my ear is messed up, but tubes would not fix it, as I'm past the age. One nurse practitioner put me on Mucinex D, and it worked like magic. I use it only as needed."

• Mik...
• Taken for less than 1 month
• June 30, 2017

For Cough and Nasal Congestion "Had congestion for 3 weeks. Doctor gave me antibiotics and suggested Mucinex D twice a day. The first two days seemed to help congestion somewhat, but I had no appetite and was somewhat anxious. The third night, I took it at 11 p.m. and slept about 2 hours. Woke up with my heart racing and anxiety. I couldn't sleep and was pacing. Effects started to wear off at 10 a.m. Wish I had seen this site first."

• Anonymous
• Taken for less than 1 month
• October 26, 2018

For Cough and Nasal Congestion "I have an insanely bad cold, and my sinuses are so stopped up. I took this thinking it would bring me some relief. It sure did, along with anxiety and feeling like I was cracked out of my mind!!!! Now I’m sitting here at 12 AM reading everyone else’s reviews when I have to go back to work tomorrow after 2 days off...ugh. No one told me the pseudoephedrine would make me so wired!"

• Anonymous
• September 6, 2010

For Cough and Nasal Congestion "I am definitely feeling better as far as not being congested goes. However, I am writing this at 4:52 am because I have not been able to sleep all night long. I took the medicine at about 8 pm, so I probably won't be doing that again."

• slu...
• January 5, 2017

For Cough and Nasal Congestion "Have taken Mucinex D several times over the past few years with congestion. It is the best thing out there to make me feel better during the day, but I only take it in the morning with food. Even then, I usually don't sleep great at night but do not experience the insomnia others are talking about."

• Anonymous
• September 27, 2020

For Cough and Nasal Congestion "I had the worst experience with this Mucinex D Maximum Strength. I could not stop coughing and felt my blood boiling inside my body. This gave me anxiety and insomnia. Do not try it unless you want to feel like you're dying."

• Kur...
• November 15, 2016

For Cough and Nasal Congestion "Took first dose at 8:30 a.m. and went to work. Definitely cleared me up, so, as directed, took another dose at 12 hours (8:30 p.m.) and went to bed feeling tired. As the medication took effect, I became restless and tossed and turned and found myself unable to sleep. 1:30 a.m. and I'm learning of my mistake. Packaging should definitely be updated to disclose this fact. Works great to clear sinuses, but I won't take it again at night due to the side effect of insomnia."

• all...
• March 10, 2015

For Cough and Nasal Congestion "I’ve been coughing for days (unable to sleep because of the cough), can’t breathe through my nose and have a congestion headache. Took 2 pills in the morning, and it took a while to kick in, but several hours later I realized I could actually take a full breath through my nose, the headache improved, still coughing but not quite as bad. I didn’t have any issues with feeling jittery or wide awake."

• goo...
• April 20, 2012

For Cough and Nasal Congestion "My PCP suggested I take this to help with severe congestion. I took 3 doses of the 12 hours (max strength) at the prescribed intervals. Basically, one that afternoon, then one the next morning, and one that evening. That night, I could not sleep. I have never had problems sleeping and usually could find some way to read for a bit or do a relaxation exercise in the event it took longer than normal. I'm normally asleep by 10 or 11. It's now 4 am, I am not one bit sleepy, and I have to get up for work in 2 hours. Should be an interesting day."

• Hin...
• Taken for less than 1 month
• November 20, 2019

For Cough and Nasal Congestion "Do not take this at all unless you want to be up and feeling like you are never, ever going to sleep again. I was taking DayQuil until my very smart girlfriend offered me a Mucinex in the middle of the night. Never, ever take this or any other med containing pseudoephedrine. Whatever you are going through is not worth the anxiety and insomnia. I also threw up as well, which tasted exactly like the Mucinex."

• Joy...
• December 31, 2012

For Cough and Nasal Congestion "This worked well for me. I had what felt like a pretty bad cold... headache, nasal and chest congestion, and a generally run-down feeling. Stayed in bed the first day, and on the second, I took the prescribed dose of Mucinex D - 2 tablets at 7:30 pm. I didn't experience the insomnia others spoke of, but maybe my perspective is different because I KNOW that if I hadn't taken it, I'd be up blowing my nose and coughing all night. Yes, I did wake up a few times more than usual, but I wasn't miserable when I did."

• SSF...
• Taken for less than 1 month
• February 20, 2025

For Cough and Nasal Congestion "I highly recommend Mucinex D. First of all, I am not tolerant of many cold/allergy medicines. I was prescribed Mucinex D (2 pills every 12 hours) for my chest and nasal congestion. It seems everything I take affects me with anxiety, drowsiness, dry mouth, nausea, or something. So, to be safe, I took only 1 tablet to start. Within 1/2 hour, my cold symptoms were so much better, and I had no side effects from the pill. Then, 6 hours later, my cold symptoms started getting bad again. So, I took 1 more at 6 hours. Long story short, I have been taking Mucinex D for 3 days. But my schedule is 1 tablet every 6 hours, instead of 2 every 12 hours (still at the limit of 4 in 24 hours). I have had no trouble sleeping (except for the cough and nasal stuff). I am not sleepy, or anxious, or anything. In fact, I feel great. It does seem to be an appetite suppressant too...bonus! I am so glad I took the chance of making my own dosing schedule. It works!"

• Sha...
• November 24, 2016

For Cough and Nasal Congestion "I took Mucinex, the capsule, as directions state, to help me with severe congestion the night before Thanksgiving. After reading the reviews, I must say it had the opposite effect on me, it made me tired. The best way for me to describe it was I felt like I took a muscle relaxer, but not as strong. It just made me feel slightly weak and needed to sleep. Although it definitely helped relieve my symptoms from being congested, such as my headache and cough. So for my sake, I would want to take it at night and definitely not have to drive anywhere. I am not one to take medication or any drugs for that matter."

• Anonymous
• July 16, 2008

For Cough and Nasal Congestion "I read all the information on the previous pages. The box of Mucinex D that I just purchased has a much higher mg of active ingredients than what was reviewed. Mine has 1200 mg guaifenesin and 120 mg pseudoephedrine HCl per pill. The information on the other page was regarding HALF those amounts. So be sure to take the correct dosages into account."

• Ala...
• November 16, 2016

For Cough and Nasal Congestion "I used Mucinex D last year, taking the recommended 1 pill every 12 hours, and was fine, it helped so much with my horrible sinus infection. I'm on day 3 of some nasty congestion and decided to take Mucinex D last night at 9 pm. DO NOT TAKE THIS IN THE AFTERNOON OR NIGHT IF YOU WANT TO SLEEP. I laid down at 10 pm because I felt like crap. I laid in bed until 2 am and finally fell asleep for a whole 3 hours. I do like this product, but I would just recommend taking it right away in the morning since it lasts 12 hours."

• Anonymous
• December 5, 2011

For Cough and Nasal Congestion "I have experienced fluid in my ears for almost two years. Consulted with two ear and nose specialists and with an allergist. Tried three types of nose sprays and other natural options, like additional vitamin C, pollen defense, and the neti pot. Nothing worked until just recently. I developed a severe cold and took Mucinex D. To my amazement and happiness, the fluid drained from my ears. Clear ears! Problem - one cannot take Mucinex on a permanent basis."

• Hei...
• Taken for less than 1 month
• June 15, 2016

For Cough and Nasal Congestion "Took my first dose of Mucinex D at 10:30 a.m. yesterday, took a small nap around 12:30 for about half an hour, and have been awake since. It's now 8 a.m. the next day. Yes, I finally feel relief in my sinuses. I no longer look like a puffy-faced Darth Vader. It sounded like it's cleaning up a ton of congestion, but sleeping is not in my favor. Ugh, but I'm glad it's clearing things up for me. Just need some sleep."

• Anonymous
• April 10, 2012

For Cough and Nasal Congestion "I experience sinus problems frequently, mostly from allergies, probably. I have headaches and a stuffy nose, etc. This medication is wonderful. I should receive money for how many times I have recommended this to people. I feel like I can even think clearer when I take this. I rarely experience side effects. Maybe one time I had dizziness. Great product."

• Lio...
• Taken for 10 years or more
• December 18, 2015

For Cough and Nasal Congestion "My doctor told me that the key to Mucinex working effectively is to take it with a full 8 oz of water and then keep drinking water throughout the day. The water is what helps thin it out. If I don't drink plenty of water with it, it doesn't work. When I do, it often works all day and night. I take it early in the day because it does keep me awake. I hope this helps, good luck, and I hope you feel better. * Use a humidifier too, the moisture in the air keeps you from drying out."

• J20...
• Taken for less than 1 month
• January 7, 2019

For Cough and Nasal Congestion "After being diagnosed with bronchitis, I took the prescribed dose of 1200 mg at 11:30 am. It’s now 3:07 am the next day, and I am still not able to go to sleep! Thank God I did not take it every 12 hours as recommended, I would be going crazy like the other reviews! So nervous about if I will be falling asleep at work or still wide awake in a few hours. No rest in sight. I guess it is the pseudoephedrine in it that is keeping me awake."

• Hel...
• March 31, 2016

For Cough and Nasal Congestion "It dehydrates you like crazy, and I could not drink enough liquids. My throat got so dry it caused me to cough uncontrollably. For the past 3 nights, I could not sleep... Even took 10 mg of Ambien, which usually knocks me out cold... But it didn't work. I just found this site and learned that my insomnia is caused by Mucinex D. Not worth the lack of sleep!"

• Anonymous
• February 15, 2010

For Cough and Nasal Congestion "I have suffered sinus problems my entire life. I have found that using a saline sinus wash 2 times a day (morning and evening, before I shower) and taking Mucinex D when I am having really bad episodes seems to be the perfect combo. I was also told that you should not take Mucinex D for more than 5 days. If you take it for 5 days, you should go off of it for 15 days before going back on the medication. The sinus wash is the secret. I also use a swimmer's ear solution in my ears a couple of times a week, and this seems to help with the buildup of bacteria in the fluid that is always in my ears. I hope this helps."

• QT ...
• December 10, 2013

For Cough and Nasal Congestion "Yep, I took ONLY 1 Mucinex D almost 24 hours ago for the 1st time, and I'm still up. During the 1st 12 hours, I didn't sleep a wink because I took this pill right before bed. My nose was dripping the whole night. This thing definitely unclogged my sinuses without the uncomfortable burning sensation of inhaling and the pain behind my face. My sinus relief lasted the whole 12 hours! I kept thinking it would wear off sooner. Throughout the day, I haven't stopped sneezing, and it's a scary sneeze, as in a loud scream. I've been scaring people all day. This is not my normal/typical sneeze. I usually sneeze like a silent little bunny! This is how I found this website to find out what this sneezing is all about. Doctor prescribed."