Fam-trastuzumab deruxtecan and Constipation: What Users Say

• Ano...
• Taken for 6 months to 1 year
• June 24, 2025

For Breast Cancer, Metastatic "Was told with LMD I had 3-6 months to live. Been on Enhertu for 10 months. One treatment every 21 days. I get Emend and steroids with the infusion. These stop the side effects. I have not had any nausea or vomiting, but have had some constipation and sometimes diarrhea. It's been the easiest of all the meds I've tried. It seems to be working systemically, my LMD has been stable, no progression so far. Grateful to have something that is finally working."

• Ano...
• Taken for 1 to 6 months
• April 3, 2025

For Breast Cancer, Metastatic "Had done #6 cycle and dosage had reduced to 80% after the 2nd infusion due to liver dysfunction. The side effects are bowel system haywire, nausea, constipation, diarrhea, skin rashes, body heat, hair loss, and so on. The side effects are not getting better after each cycle. So helpless!!!!"

• Ano...
• Taken for 1 to 6 months
• April 3, 2025

For Breast Cancer, Metastatic "Had done #6 cycle and dosage had reduced to 80% after the 2nd infusion due to liver dysfunction. The side effects are bowel system haywire, nausea, constipation, diarrhea, skin rashes, body heat, hair loss, and so on. The side effects are not getting better after each cycle. So helpless!!!!"

• Ano...
• Taken for 1 to 6 months
• August 17, 2025

For Breast Cancer, Metastatic "Hair loss, stomach pain, fatigue, nausea, back pain, constipation, increased hunger, mouth sores. It takes 9-10 days out of the 21-day cycle to recover after each infusion."