Donepezil and Tiredness: What Users Say

• Anonymous
• Taken for less than 1 month
• March 24, 2021

For Alzheimer's Disease "My poor mom was up all night with bad nightmares and talking all night in a state of confusion. Today she is like a zombie with no appetite and refuses to get out of bed because she is so tired. I should have looked up the side effects first. I am livid with the doctor that prescribed this."

• Tee...
• Taken for 1 to 6 months
• January 12, 2020

For Alzheimer's Disease "My first experience with donepezil 10 mg was nasty. It affected my sleep in a bad way and made my memory, speech, and basic cognitive functions worse, and I was continuously lethargic. After 2 months on the drug, I can honestly say I feel a huge difference (for the better). There is a big improvement in both my memory and speech, and it's really made a difference in my day-to-day life and daily tasks."

• Car...
• Taken for 2 to 5 years
• May 15, 2024

For Alzheimer's Disease "Been taking donepezil for a little over 2 years. Began on a very low dose, had zero side effects. Currently taking the max dose, stools are rather soft but not watery. Often feel very tired, however, I force myself to walk and do light exercise. I have tried to enter Alzheimer's studies but pass all cognitive tests with high scores and have not been accepted in any study. Assume medication is helping or I was misdiagnosed."

• MGG...
• Taken for less than 1 month
• July 29, 2025

Donepezil for Alzheimer's Disease "After my initial diagnosis, my neurologist put me on this drug. We have had to reduce the dosage twice. I’m down to 2.5 milligrams and still feel tired and in a fog on and off. I have had a few days where I felt pretty good like I used to, but I only remember one or two nights that I slept through the night since I’ve been on this drug, which is not very long. Several weeks. Now multiple bowel movements a day. I feel drugged."

• Anonymous
• August 2, 2011

Donepezil for Alzheimer's Disease "My mother took Aricept 5 mg for one week. She has vivid dreams and cannot tell if they are in fact dreams or real. Also, very tired."

• Ton...
• Taken for less than 1 month
• May 29, 2023

For Alzheimer's Disease "It woke me up at 2 a.m. every morning. I was exhausted, so I stopped. The doctor told me to take Tylenol PM, what an ass!"

• Kei...
• Taken for less than 1 month
• November 7, 2024

"Since taking this new pill, I have been awake all night, feeling tired all the time, sleepwalking, and lots of gas."

• Don...
• July 30, 2024

For Mild Cognitive Impairment "Dizziness, thirst, confusion, weight loss, constipation, trouble sleeping, tiredness, loss of appetite."

• Lad...
• Taken for 1 to 6 months
• April 8, 2025

Donepezil "Worsened depression, vivid dreams being confused for reality, tiredness, and diarrhea."