Collagenase clostridium histolyticum and Soreness: What Users Say

• Anonymous
• Taken for less than 1 month
• December 24, 2019

For Dupuytren's contracture "I would not recommend this procedure at all. I had a reaction to the injection, which caused bruising on my arm up to my armpit. It felt like my whole right side of my body was just not quite right, however, my Dr. said that it just couldn't be from the shot. It is a week and a half later, and my arm still hurts, and my little finger is bruised, swollen, and aches. The procedure was painful, and the manipulation of my little finger three days after the shot hurt, and I felt the tearing of the cord or whatever. My finger is still so swollen and bent that I'm not sure how straight it will be after it heals up, hoping upon hope that it actually heals and I can use it again. Again, I would not ever do this again!"

• Anonymous
• February 10, 2021

For Peyronie Disease "On my second shot, but I think this is it after reading some of these comments. I'm praying to God that I don't get any shorter than I am now!!! I'm still tender at the base after one week. It looks better, but trying to stay away from an erection."

• Gre...
• Taken for less than 1 month
• February 25, 2022

For Dupuytren's contracture "My pinky and ring finger were pretty bent, and when I saw the advertisement on TV about Xiaflex, I decided to try it. It’s a very simple procedure. They numb your hand up and inject the drug. Then, after a day wait, they numb it up again and manipulate your hand to free up the cord(s) that are bending your fingers. The shots for numbing hurt about exactly as much as you would expect them to. The pain was not bad at all. You don’t feel the Xiaflex drug injections because your hand is already numb. Xiaflex dissolves the cord tissue and frees up your fingers to bend back. In my opinion, the pain of the injections was nothing compared to the soreness created by the drug itself as it dissolves the tissues. It’s bearable, and I just used a little Tylenol, which made it OK. It was very sore for the first week, moderately sore for the second week, and lightly sore for the third week. It was not that bad, and the results were awesome. I recommend it!!"