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Qulipta for Migraine Prevention User Reviews

Qulipta has an average rating of 7.6 out of 10 from a total of 83 reviews for the treatment of Migraine Prevention. 66% of reviewers reported a positive experience, while 14% reported a negative experience.

Qulipta rating summary

7.6 average rating out of 10

83 ratings from 87 user reviews.

Compare all 49 medications used in the treatment of Migraine Prevention.

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Reviews for Qulipta

  • Mys...
  • Taken for 1 to 6 months
  • March 25, 2022

"Qulipta has been life-changing. I used to get roughly 20 migraines per month, but now I might get 1 or 2 max. I also get very few non-migraine headaches now. I used to have them daily. I use a fraction of NSAIDs I used to. When I first started taking Qulipta, I had some nausea for about 2 weeks but not anymore. I have noticed that I don’t overeat as much so I gradually lost 10 of my extra lbs. I am getting much more done day-to-day without the migraines, and do not need to contend with the side effects of all the triptans I used to take. I do not seem to be as sensitive to migraine triggers. Have not noticed any mood changes or constipation (but I still take a daily magnesium supplement and drink a lot of water, so that may help out). It’s a humongous relief to find a preventative that works since the old options gave me such bad side effects and didn’t really work (beta-blockers, tricyclics, anti-seizure medications, etc.). I really feel like myself again, after so many decades."

10 / 10
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  • Son...
  • Taken for 1 to 6 months
  • November 17, 2022

"Qulipta is a game changer, a lifesaver for me. I have chronic intractable migraines. I've been through so many failed meds and treatments. I've had 25-30 migraines a month for 25 years. I just had 13 days migraine-free. Thanks to Qulipta, I have hope for the future."

10 / 10
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  • Fru...
  • Taken for less than 1 month
  • February 25, 2022

"Didn’t do anything but make me constipated, fatigued, and depressed. Took it for migraine aura treatment (I get frequent visual auras). Not sure why a CGRP inhibitor would help that subtype of migraine but alas. I was completely constipated for days - literally couldn’t go despite Miralax, prunes, etc. I was extremely fatigued and also dealt with depressive symptoms that aren’t typical for me. Not a pleasant experience. In my opinion the long term safety profile of these drugs should be studied further before they are prescribed en masse. Clearly blocking CGRP has many effects on the body besides just migraine (which didn’t even work for me)."

1 / 10
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Frequently asked questions

  • EAJ...
  • Taken for 6 months to 1 year
  • November 30, 2022

"This is a miracle drug! I am 51 and have had hormonal migraines since I was pregnant 25 years ago. I first started with Qulipta a year ago, right after it was first approved by the FDA. I was the first patient my neurologist prescribed it to. Lost about 15 lbs over the course of a year and have had maybe 5 migraines total this year. No side effects other than weight loss. No issues getting it with the Qulipta card either. Wonderful results!"

10 / 10
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  • Ani...
  • Taken for 1 to 6 months
  • June 13, 2022

"I've had migraines for 8 years and have been on many pharmaceuticals for prevention and rescue. I started Qulipta 60 mg a month ago and immediately on starting, I had chest pains that went into my back and shoulder. I tried taking a smaller dose, 30 mg and 15 mg, and still had the chest/back/shoulder pain. I was also extremely fatigued, and my blood pressure shot up. I had a few medical appointments, and my blood pressure was 190/80. I visited my GP, who is easier to get in to see than my Neuro. She did an exam and an EKG and noted that it was not normal. I have a stress test scheduled for next month. I stopped taking it 2 days ago, and the chest pain was instantly reduced by 80%. It's slowly going down the rest of the way. This is not listed as a side effect even though I know a few people who have had this problem. Please be careful with this drug. I never had heart problems before this, and I hope that the damage is not permanent."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • February 24, 2022

"Ease of use: Very easy, if you can swallow pills; Dosage: 60mg tablets once daily. Benefits: None. Side effects: Mood altering (made me extremely angry), Constant feeling of hunger (even after eating), Extreme fatigue (That's saying something because I also have narcolepsy). Provided no relief of the migraines, actually felt worse taking the medications. I felt it was not worth taking Qulipta due to the added side effect and the lack of help it provided. I was told by my doctor that 'those aren't known side effects' and to give it another try. I had originally been taking the medication during the day, decided maybe taking it at night might make a difference. I started the medication, at night, the next morning, the fatigue was overwhelming, extremely hungry, and about 2 hrs later I became extremely angry. Contacted the doctor, stopped taking the medication. Since stopping, my mood has regulated back to normal (no longer angry), no hunger pains, narcolepsy back under control."

1 / 10
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  • Sai...
  • Taken for less than 1 month
  • April 11, 2022

"Within 5 hours of one 10 mg dose, BP rose to 196/96 and stayed there. One week later, it has not normalized. Qulipta is not BP neutral as stated by the manufacturer. It did not stop migraines and caused more headaches due to the rise in BP."

1 / 10
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More FAQ

  • Mig...
  • Taken for 1 to 6 months
  • July 2, 2022

"I have had almost daily migraines since I was 13 years old, and I am now 69 years old. I started taking Qulipta 60 mg in mid-January 2022. I have not had one migraine since! I have not had any side effects. I have been on every other preventive medication, which had weight gain and sleepiness as side effects. They only reduced my headaches to 4 times a week. Triptans didn't help at all to abort a headache. Qulipta is truly a miracle for me."

10 / 10
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  • mrh...
  • Taken for 1 to 6 months
  • April 13, 2022

"I’ve been taking the 60mg pill for about three and a half months, and it’s helped prevent migraines from a couple of very common triggers: weather change, odors, and flickering lights. It also makes the migraines I get usually much less painful and easier to get rid of, or to stop from starting with Fioricet. It has reduced my appetite, but I’m slowly gaining weight and eating less, I have to figure that out. I’ve used Aimovig and Emgality too, and this is the best one."

8 / 10
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  • Rlo...
  • Taken for 1 to 6 months
  • December 1, 2021

"This medication works amazingly to prevent one type of migraine. It will not prevent a migraine that is caused by any other triggers, but if you abruptly stop like me, I had withdrawal-like symptoms because I ran out over the holiday weekend. After 72 hours from my last dose, my body didn’t handle it well at all."

9 / 10
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  • Tiz...
  • Taken for 1 to 6 months
  • November 3, 2022

"I have been on Qulipta for migraines for about 4.5 months. (7-year history with constant migraines.) My doc gave me 60 mg, but I was incredibly tired and falling asleep. So much so, it was like I was in my 1st trimester of pregnancy again. (Not pregnant now.) I decided to break it in half and only take 30 mg daily. The 1st week or two, I still had a lot of headaches, but sumatriptan helped. Then the migraines pretty much stopped! I was constipated, but that pretty much has evened out. However, and this is a big one… in the last month to month and a half, I have lost half my hair! (I’m a 43-year-old female with long fine hair as it is, and losing half is extremely upsetting to say the least.) Now, I have also been on Bupropion for 14 months, and there is a 1% chance of losing hair on that. Also, maybe perimenopause could be kicking in… but to lose that much hair that quickly???! I stopped Qulipta and Bupropion both cold turkey last week to see if my hair will stop falling out or not."

4 / 10
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  • Fru...
  • Taken for 1 to 6 months
  • February 16, 2022

"Qulipta helps with migraines. My other meds stopped working for me. It does not prevent them, but the pain does not last as long while on the medication. My problem is the company makes it almost impossible to get the drug. I got a sample with the savings card. The QR code did not work to activate it, neither did the reacting feature. It does not come with the information for the pharmacy to use. I called Qulipta customer service. It took them an hour to register my card and two weeks before I could get my first prescription from my pharmacy, due to lack of info again by Qulipta. I refilled my second month fine. As soon as I get my second refill, Qulipta starts calling me about my savings card. They are making me call them multiple times saying they need more information before they will allow me to use their savings card a third time. It’s $1,200 a month without the card. They don’t leave any details of what information they need. When I try to call back, everyone is clueless as to why."

3 / 10
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  • AGC...
  • Taken for 1 to 6 months
  • September 12, 2022

"I'm on a laundry list of meds for migraines and other chronic health conditions, so take my review with a grain of salt. Qulipta is great! I have chronic vestibular migraine and started taking Ajovy as a preventative, which lowered my daily pain level but failed to take away my dizziness and vertigo. Adding Qulipta 30 mg to my preventative regimen basically fixed my debilitating, disorienting dizziness! One weird and really strong side effect I experienced: For the first ~5 nights after starting a new dose, I had severe insomnia where my head felt extremely clear, and I was totally wired, wide awake, and unable to fall asleep. Luckily this faded and wasn’t too unpleasant, but weird!"

7 / 10
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51 Report
  • Mig...
  • Taken for 1 to 6 months
  • March 28, 2022

"Qulipta is my miracle drug. I rarely have migraines & take a Ubrelvy if I do, and it’s gone in an hour. I’m on 30 mg due to bad nausea with 60 mg. I did get migraines again with COVID, and Qulipta stopped working for a short time, but the doctor gave me a nerve block (simple in-office, few tiny needles) and was back to normal with Qulipta working again. Highly recommend!!! I have my life back!!"

9 / 10
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  • Mig...
  • Taken for 1 to 6 months
  • March 10, 2022

"I have had an incredible experience with Qulipta. While I struggled with dry mouth the first 2 weeks, it’s since gone away and my migraines have dropped drastically. I have also lost 10 lbs, which has been awesome but might not be great for everyone."

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  • Mig...
  • Taken for 6 months to 1 year
  • January 16, 2023

"Started taking Qulipta (60 mg) close to a year ago. Initially, the only side effect symptom was constipation, but no migraines. After four to five months, a few breakthrough migraines. Then stomach pain shooting to back and shoulder, insomnia, anger/agitation, ringing in ears, all accelerating to unbearable levels. Stopped taking a few days ago, and my nerve pain has calmed somewhat, but stomach pain continues along with persistently loud ringing in ears. I was going to break it in half to wean off, but I don’t think my stomach can bear it. It’s ironic in that my migraines usually begin with stomach pain and that the one and only medication that helped is now causing stomach pain along with other symptoms. Usually, adverse reactions to medication start at the beginning of use for me, not long term, so it took a while to realize it was the Qulipta."

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  • Mom...
  • Taken for 1 to 6 months
  • September 2, 2022

"I have suffered with migraines for over 20 years with absolutely no relief. I've literally tried almost every med out there and lost hope! Daily constant migraines. I started Qulipta about 6 weeks ago and figured it would fail like the rest. My migraines were reduced by almost 70%! Life-changing! I had 11/39 migraines compared to daily! Just to show you never give up hope of finding the right med out there. I’ve tried every single med that has been released… good luck everyone."

10 / 10
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  • Deb...
  • Taken for 1 to 6 months
  • March 30, 2022

"I’ve been on Qulipta 30 mg for almost 6 months. It seems to have lessened them some, however, they are no help for migraines caused by weather changes and stress. We live in the South, and the barometric pressure swings like crazy, causing my migraines. I feel like they aren’t as bad as they were, and I have been on every drug made for migraines and seizures. I go back to my neurologist next month, and he may up the dosage. I have lost weight because I have no appetite. It hasn’t affected my depression or any other health concern, so I’ll stay on it until my doctor does something different."

10 / 10
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  • Rob...
  • Taken for less than 1 month
  • March 3, 2023

"I suffered two TBIs (traumatic brain injuries) in 2018 and 2020 from falls that caused injuries to the left side of my brain and cervical neck. Like most, I have been on just about everything as my headaches are daily, and I have what's called complex migraines, basically stroke to the left side of my body, including my vision. My recent meds, Nurtec and Ajovy, which were giving me relief, stopped working, but I had been on them for 1-2 years. So, my neurology doctor had me try Qulipta 60 mg daily, and so far it's been the best by far!! That being said, I have only been on it for 2 weeks and will wait until 30 days before deciding to make a permanent change, but this is the best I have felt in some time. I have not noticed any major side effects as of yet, but I will keep an eye out for them from some of the answers on this thread. Wishing all of you well battling severe migraines and hope you find a medication that works for you to bring relief and give you your life back :)"

10 / 10
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  • Eri...
  • Taken for 1 to 6 months
  • July 30, 2022

"I was skeptical when I tried Qulipta because my doctor had put me on Nurtec last year, which was absolutely horrible and actually made my migraines worse and more frequent! I was prescribed 60 mg Qulipta earlier this year and am shocked I’ve only had 1 migraine in 4 months and no side effects."

10 / 10
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  • Bon...
  • Taken for 1 to 6 months
  • September 19, 2022

"I've been on Qulipta for about 2 months. I've only had severe migraines since I was shot in the head twice almost 5 years ago. (Yes, for real.) I was a paramedic, and it was my co-worker EMT who shot me. Anyway, I've tried everything else there is (that insurance would pay for). Nothing has helped. I feel like nobody gets that this is a different type of headache than a migraine. I've had migraines before, and this is worse. It seemed at first that it was helping some, but the headaches are slowly getting their normal worse again. Then a good friend of mine kindly told me today that I've been struggling with anger more than usual (a common problem with traumatic brain injuries). I've thought about it, and the only thing that's new or changed is the Qulipta. I don't know. It's all so discouraging."

4 / 10
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  • SC ...
  • Taken for less than 1 month
  • July 30, 2022

"Started 60 mg of Qulipta for chronic migraines post-COVID. Day 7, I can hardly function. Severe fatigue and anxiety and nausea. I can't tell any difference yet on the effectiveness of preventing migraines. I will try to not give up yet, but my blood pressure is also elevated."

4 / 10
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  • QHC...
  • Taken for less than 1 month
  • April 6, 2023

"I have been on Qulipta for 17 days so far, and I haven't had a migraine yet! I suffer from chronic migraines - I get about 14-20 migraines a month. I have tried many different preventative drugs, and I have never been able to tolerate the side effects. So far, I have mild constipation, itching, mild hives, and my feet and hands are swollen. I can probably handle these, but it seems as if the fatigue that comes with this drug is getting worse. I am hoping this will subside, because I truly enjoy not having a migraine."

8 / 10
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24 Report
  • Mig...
  • Taken for 6 months to 1 year
  • July 6, 2022

"I’ve been on Qulipta for 6 months now. It has worked better than anything else I’ve tried. No mood alteration, which has been my biggest problem with others. I noticed my BP went up as well, but it was always too low anyway. It may have increased my trouble with constipation, but it’s hard to say. My biggest complaint is weight gain. Almost 10 lbs despite almost daily exercise and a very clean diet. I’m not sure what is going on since I’ve read so many with weight loss. Dr. won’t address the concern since I’m not obese."

9 / 10
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28 Report
  • Ash...
  • Taken for 1 to 6 months
  • May 28, 2022

"I was on 60 mg for about 6 weeks, and honestly, it felt like I was taking nothing each day. I had raging migraines daily and went through two prescriptions of triptans for two months to try and survive. I have much more success on the injection preventatives in this class than this drug, unfortunately."

1 / 10
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28 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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