Qulipta for Chronic Migraine User Reviews

• Kat...
• Taken for 6 months to 1 year
• May 12, 2024

"After 30 years of chronic migraines, I am free. Prescribed Qulipta 8 months ago. I have taken every migraine headache med that's been on the market. I mean EVERY. Qulipta saved my life. I can now make plans and actually attend - no more migraines. Wish my mother was still living. She would be so happy for me. Thank you so much."

• Mir...
• Taken for 1 to 6 months
• August 10, 2023

"I've suffered from chronic migraines for 25 years, with over 20 pain days a month (15+ migraines and 5+ headaches a month). Most severe enough to require medication. I started Qulipta 2 months ago, and since about 2 weeks into treatment, I haven't had a single migraine or headache that required pain medication. It feels too good to be true, but it's working miracles as of right now."

• Ano...
• Taken for 1 to 6 months
• April 24, 2025

"Triggers severe RLS! Not sure if it works because I am dealing with migraines on top of cervical instability that triggers occipital neuralgia and trigeminal neuralgia, which makes it hard to differentiate if it's a true migraine or from my neck the past couple of months. I am about to move my dose to the morning instead of at night to see if I am better able to tolerate it due to realizing it has triggered my RLS to break through my RLS medication, which makes it impossible to relax and sleep when taken at night. No other issues, side effect-wise, except for apparently CGRP inhibitors trigger full body RLS for me, despite taking a 24-hour RLS medication. I found no mention of this med causing RLS but did find plenty of studies linking CGRP inhibitors to RLS in patients. So if your legs start jumping at night, then yes, it's Qulipta."

• Sk8...
• Taken for 1 to 6 months
• May 10, 2025

"I have only been taking Qulipta for 2 months, but it has completely changed my life. I have gotten a few migraines each month with temperature change and whatnot, but I was getting 15+ a month. I feel really good and hope it continues. It's definitely worth trying. This is the best I've responded to a migraine medication. I also take Ubrelvy, which works great for me as well."

• adi...
• Taken for 1 to 6 months
• July 31, 2023

"I have tried nearly every available drug for migraine treatment. Nearly my entire life, I have just been treating them as I get them with the typical drugs like triptans. I found out over the years that I was allergic to most preventives. Qulipta has been like a magic potion for me. I hardly ever get full-blown migraines anymore. And when I do get them, they are very mild compared to what I was living with before. I have my life back. I no longer live in fear that a migraine will strike and prevent me from either driving home or ruining an event or even losing my job. The only issue I have now is constantly battling my insurance company to keep paying for it. They want me to keep trying these other drugs again and again that I am allergic to or that are ineffective for me."

• Anonymous
• Taken for 1 to 6 months
• February 10, 2024

"I have had migraines since I was 7 and they run in my family. Now I'm 51 years old and for the first time in my entire life, I have gone 6 weeks without a migraine. Constipation is being managed with MiraLax and I had to learn to take Q first thing in the morning to protect my sleep. The first two weeks of taking it at night, I couldn't sleep through the night, and I had insanely vivid dreams. Moving it to the morning took care of that. It does not make me sleepy during the day. I have an entirely new way of living and realize what a fog I was in on Topamax. Grateful for the scientists who figured this one out!"

• Not...
• Taken for less than 1 month
• June 19, 2024

"I see so many comments about this not working. Here’s my take as someone with chronic daily complex migraines with aura (who’s tried most other medications). 1. Try it for 1 month straight at 60mg. Take it at the same time of day. 2. Severe nausea at first (2 weeks). It will lessen. 3. Bad constipation. You need to drink at least 1L of liquids per day, take 100mg of a stool softener and eat fiber. If you don’t, bowel movements will be hard to pass. 4. It will begin to reduce your migraines slowly after week 3. I still get them daily, but both the aura and pain are less."

• Hea...
• Taken for 6 months to 1 year
• January 17, 2025

"I am on the Botox and Aimovig injections (for a few years) with Qulipta recently started. The Botox and Aimovig lessened daily migraines, but I started having hemiplegic migraines, which mimic stroke symptoms. The Qulipta seemed like a wonder drug for the first few months, minus the constipation, which is a good thing for me. However, within the last two months, I have started having right shoulder and collarbone pain, excruciating stomach pain, and back pain. The pain even went down my right leg in the nerves and the muscles. Back pain is worse than before I had back surgery years ago for a broken back. The doctor couldn’t find anything wrong with any of these problems. So after reading most of these reviews, I’m beginning to wonder if this is a symptom of this Qulipta? I do have the agitation/anger, ringing in the ears, and exhaustion as well. Disappointed."

• Con...
• Taken for 1 to 6 months
• January 7, 2025

"Qulipta has been a Godsend. I have suffered from daily headaches and migraine headaches for over 20 years and thought there was no end to the suffering. I've tried every supplement and medication there is out there and thought the rest of my days were to be spent in pain. I kept seeing commercials for Qulipta and asked my doctor to prescribe it and thought, why not try this too. Well, thank God I did because I almost immediately began seeing improvement. I went from taking migraine medicine 3-4 times a day (which is too often) to I can't remember the last time I have taken it, and this has been months ago. Such a blessing and no side effects. Thanks to the makers, you've changed my life!"

• Hep...
• Taken for less than 1 month
• July 30, 2023

"Since starting Qulipta, I haven't had a migraine. I have never gone 12 days without a migraine before. I am really concerned about the cost of the medication. Since I am on Medicare, I don't qualify for the savings program, and adding the cost of another script might not be doable."

• Chi...
• Taken for 1 to 6 months
• July 1, 2023

"I've tried seven other medications (including injectables) - this is the first medication that has actually decreased my pain! I have a Chiari malformation, plus chronic migraine. After just a few weeks on 60 mg Qulipta, my daily head pressure was less, and I haven't had a full migraine at all (now six weeks into treatment). Zero side effects (though I wouldn't complain if I had the weight loss side effect!)."

• Con...
• Taken for 6 months to 1 year
• September 26, 2023

"I have been using Qulipta for about six months now, according to my neurologist's recommendation. 60 mg was far too much for me, so I halved the dosage. My hair has begun to fall out. I'm experiencing way more than average hair loss. I also have extreme dry eyes now. Has anyone else experienced these side effects? This medication works so well for me, so I hate to stop taking it."

• Ano...
• Taken for 1 to 6 months
• June 3, 2023

"Have been taking Qulipta 60 mg nightly for the past 5 months for chronic migraines. Prior to this medication, 3-5 migraines per week. Now 1 or 2 times a month, mild migraines, usually with fast-changing weather conditions. Extreme fatigue has been the side effect. Trying an improved diet and increased exercise to try and counter fatigue."

• Anonymous
• Taken for 1 to 6 months
• May 11, 2023

"I have been taking Qulipta now for about 5 months. It has been a game changer. I was having around 15 migraines a month, and now I have 1 in 5 months. My main side effect is extreme fatigue. I have to work through that because tiredness is better than migraines. It has gotten a little easier every month."

• ckr...
• Taken for less than 1 month
• June 13, 2023

"I just recently started taking Qulipta 60 mg. I received samples from my neurologist. I was doing really well with Botox plus Vyepti, and then I had a stroke. Right after the stroke, my migraines went back to every day, and the best I could do was to tamp the pain, nausea, confusion, light, and noise sensitivity a little bit. We decided to try something different. So I started Qulipta. Three days in, I knew something was different. Even with allergy season and sinus congestion, I can almost stop the pain with a little cold medicine or dual-action medicine. I am able to think and concentrate on daily chores and paying bills. I was already tired from trouble sleeping, and Qulipta makes that worse, so I sometimes need to go back to bed after breakfast for a couple of hours; I have moved to take the Qulipta in the evening, and that is a little better."

• Dav...
• Taken for 6 months to 1 year
• January 18, 2025

"Took 60 mg daily for 8 months, it helped cut back migraine frequency. However, had significant stomach digestive issues. Stopped Qulipta, and migraines are worse and almost daily. Sumatriptan saves me. The Qulipta really works at a high physical cost."

• Lam...
• Taken for 1 to 6 months
• April 7, 2024

"I have had a chronic, left-sided migraine, 24/7 for just over 8 years. I have had every test, tried every medicine, and nothing has ever worked for me. Injections, pills, infusions, and I have even had my Greater Auricular Nerve and temporal artery removed. I didn't have much hope for Qulipta when I tried it, but much to my surprise, it worked. My headache has been 95% better since day one. I take 60mg. It has been life-changing for me."

• Ros...
• Taken for 1 to 6 months
• January 31, 2025

"I have been on Qulipta 60 mg for 1 month for chronic migraine. I am experiencing ringing in my ears, insomnia, and a dullness in affect. I am not tired but have no energy or desire to do anything. I have had symptoms of migraine, like neck pain, but no debilitating headache. Today, I tried 30 mg, hoping I will feel more human."

• 2nd...
• Taken for 1 to 6 months
• March 9, 2024

"I tried Qulipta in October of 2023. I tried to do Metamucil and other bulk products to be proactive for the constipation I read about. I put on 6ish pounds in the first week, felt bloated beyond belief, couldn’t sleep, was waking up at weird times from weird dreams… It was bad. So how did I get to giving this a perfect 10? I went back to Topamax, hated it just as much as I did before, did a TON of research on what others had posted about side effects and decided to try Qulipta again at the beginning of this year. I decided to aggressively go after the constipation and take Miralax daily if that’s what I had to do. I took my Q in the morning around 7:30 AM every day. And since I did the restart - I’ve had to use the Maxalt I normally exhausted every month in terms of the allowable pills - twice. I’m at the point where I only need the Miralax once or twice a week, I’m sleeping solidly, waking up refreshed and even working out in the morning. I LOVE QULIPTA!!!"

• Man...
• Taken for 6 months to 1 year
• March 6, 2025

"Qulipta has been a miracle drug for me and has changed my life in countless ways. I am a lifetime sufferer of chronic migraine (40+ years). Within the past few years, the episodes became so chronic I was in pain and sick almost every day. I thought I was going to be permanently disabled. I tried everything: all the off-label medications, NSAIDs, sumatriptan, acupuncture, massage, vitamins, various diets, etc. With my first dose of Qulipta, the migraine in progress went away. Within a month, the frequency reduced to 3-4 a month. Now I get a migraine episode every 6 weeks or so, and it is very easy to treat and eliminate. I have never had episodes this infrequently in my entire life. I have been on 60 mg daily for about 10 months. The only side effect I notice is slight constipation at times. If you are considering this drug, DO IT!"

• Hea...
• Taken for 6 months to 1 year
• November 5, 2024

"Qulipta is a life-changing drug for those of us who have lived and suffered through migraines. I now know what life feels like, not always trying to time when to take my abortive triptan or worrying about whether I have enough meds to get through the month. I forget that I have headaches now that I am on daily Qulipta. It has changed my life."

• Kim...
• Taken for less than 1 month
• June 20, 2024

"Had significant relief from daily headaches immediately. Did not help with aura, neck pain, or dizziness. Unfortunately, the severe constipation and stomach pain continued to worsen to the point I had to stop using this medication."

• Ell...
• Taken for 1 to 6 months
• March 16, 2024

"Switched from Ajovy to Qulipta approximately 5 months ago. Immediate improvement in the first month with an additional 3-5 pain-free days, resulting in 8-10 pain days per month instead of the 12-15 I was experiencing with Ajovy. Noticed a definite lower appetite and a resulting weight loss of approximately 15 lbs. This is a positive change for me as I have been around 50 pounds overweight for the last 11 years due to lack of exercise (which triggers migraines). Experienced increased dizziness and vertigo for the first 2-3 months, which has somewhat diminished with continued use. Also, encountered increased fatigue and feelings of depression. Switched to taking it at night, which seemed to help a bit with daytime fatigue. Unfortunately, I seem to have lost the joy I once felt doing the things I love, which is most concerning. Now, 5 months later, I am experiencing a lack of interest in pretty much everything. March has been particularly bad with variable weather. It seems like, similar to Aimovig, Emgality, and Ajovy in the past, Qulipta may have slowed down or stopped working, or I am developing immunity. I am frustrated that I am running out of options."

• Fee...
• Taken for 1 to 6 months
• December 29, 2024

"I took a cruise and flew home and immediately began having vestibular issues in June. I was diagnosed with vestibular migraines, and they were terribly debilitating. Noises, lights, and food would trigger migraines every 2 hours. I was miserable and in the ER or doctor's office weekly. I was so terrified to go out with friends, work, or family gatherings because excruciating migraines would attack out of nowhere. In order for my insurance to cover Qulipta, I had to try several other classes of medications that gave me horrible side effects. I am currently 2 months in with taking Qulipta. By the second week, I saw a drastic decrease in the daily migraines. By the end of the first month, I was only having 1-2 migraines a day, but they were manageable. Now I have a slight daily headache and maybe only 1-4 migraines a week! I don't have any side effects, which is amazing, and I have added food back. Granted, some foods are still a trigger. I hope my tinnitus resolves too. Stay encouraged!"

• Jes...
• Taken for 6 months to 1 year
• December 19, 2023

"I have been having migraines since I was 11. For the past 10 years, they were every day. I would be in pain and horribly sick for days with a migraine hangover following. 8 treatments didn't work. I ended up having to use Sumitripan every day and became chemically dependent. A new doctor prescribed me Qulipta, and within a week, my migraines stopped. I may get one every 1-2 months now. It has completely changed my life. I can be around smells and light without worrying how quickly the migraine would set in. My quality of life was seriously diminished until I found Qulipta."