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Alprostadil and Discomfort: What Users Say

Brand names: Caverject, Edex, Muse, Caverject Impulse, Prostin VR Pediatric, Edex Refill

Discomfort: mentioned by 6 users (3.3%)

Based on user experiences from 182 Alprostadil reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 17.6%
burning 6.0%
discomfort 3.3%
bruising 2.7%
soreness 1.6%
swelling 1.6%

Reviews for Alprostadil

Commonly mentioned side effects
  • Jac...
  • July 27, 2017

Alprostadil for Erectile Dysfunction "I have tried just about every erectile dysfunction remedy available over the last few years, none of which did much for me. My erections just were not strong enough to facilitate good sex for myself nor my wife, and I was losing any sensation. My urologist suggested I try MUSE, and I did. But only a couple of times. The feeling I got was like being kicked in the groin. I thought the first time was possibly only a fluke for some reason, but I was WRONG! The second time was just as bad! I have NEVER felt anything like the aching and discomfort I experienced, possibly outside of being kicked in the groin. And my erection was just as weak as ever, and my penis was so painful sex would have been impossible anyway. You can HAVE this stuff."

1 / 10
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30 Report
  • Rb1...
  • September 24, 2017

Alprostadil for Erectile Dysfunction "This medication is not that great, if you can achieve good results on Viagra, Levitra, or Cialis, any of these three drugs is a much better option. The biggest complaint about Caverject is that after injecting this medication, it literally feels like there is a burning feeling, it is very uncomfortable and significantly reduces any chance of pleasure during sexual intimacy. As the drug wears off, it feels like someone elbowed you in the groin. If it is your only option, then it may be better than nothing, but it definitely has its drawbacks."

2 / 10
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28 Report
  • Joh...
  • Taken for 1 to 6 months
  • March 16, 2019

Alprostadil for Erectile Dysfunction "While using Muse, I experienced a little discomfort. The applicator seems that it is still full of medicine. I followed all of the directions that came with the product. I noticed that my penis started to harden up a little, then quit. I wonder what I am doing wrong."

6 / 10
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24 Report
  • int...
  • Taken for less than 1 month
  • October 25, 2018

Alprostadil for Erectile Dysfunction "Tried Muse and was disappointed. Very easy to apply. It caused some thickening in my penis but not hard at all. Left me with a feeling of discomfort in the shaft of my penis for about 4 hours. Have used a pump in the past with good results, guess that I will stick with this. Have tried Viagra and Cialis in the past with poor results. Great thing with the pump, a one-time outlay and it works every time."

1 / 10
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17 Report
  • Cav...
  • Taken for less than 1 month
  • December 23, 2017

Alprostadil for Erectile Dysfunction "A little discomfort at first. Allowed more blood flow. Was hard for maybe 2 minutes, then was like a valve turned on, and it just drained away. 500 mcg version. Was a little more discomfort during play, really on the fence with this, will try a few more times, diabetic with 2 back surgeries. Last surgery took a lot of it away."

3 / 10
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16 Report
  • Anonymous
  • Taken for 2 to 5 years
  • October 26, 2022

For Erectile Dysfunction "Alprostadil injections (as part of TriMix) have really helped me to get firm erections that last for up to an hour. No side effects, just discomfort during injection and a full or tight feeling."

9 / 10
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0 Report

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