Praluent User Reviews & Ratings (Page 3)

• Lake...
• Taken for 1 to 2 years
• November 27, 2018

For Cardiovascular Risk Reduction "Have genetic high cholesterol plus cardiovascular risk. Taking statins caused myopathy resulting terrible muscle aches and pains. I have been on Praulent 75mg. Twice monthly approximately 2 years. I am a very active soon to be 70 years old however after sitting a least 10 minutes It is unbearable to raise my body and start walking as my body is very stiff. Hard to get my feet to move...I ache from my lower back down to feet...my insides feel very sore and I have developed terrible nose sores! I am afraid if I take it much longer I will be unable to walk. I was hoping that the Praulent was safe for me and in the beginning of using Praulent I was pleased with the thought of it lowering of my cholesterol and no side effects. Not sure what to do now!"

• a woman
• January 18, 2016

For High Cholesterol "After three shots, my cholesterol came down over 100 points to 152 as did my LDL, down over 100 points. But am not happy with side effects of sinusitis and now earache. Whole face is throbbing from neck to face. Not sure if pain in arm is part of side effects. Am fearing other side effects noted on bladder infection. First three shots were samples, next will cost me about $50 a shot; having problems with prescription...pharmacy still working with Pharmaceutical Co. Will ask to discontinue even if all other statins have not helped.I am a 79 year old female."

• HAPPY...
• Taken for 5 to 10 years
• December 14, 2023

For High Cholesterol "Been taking since it was experimental, over 5 years now with NO side effects before taking bad cholesterol was near 300 after the test it was around 50. I do and have recommended this medicine, it is a very GREAT med!"

• Lucy
• Taken for 1 to 2 years
• August 7, 2019

For Cardiovascular Risk Reduction "I’ve taken Praluent for over one year. I can’t identify any side effects. I’m unable to take statins because of pain, muscle weakness, and hair loss. I’m only on Zetia and Praluent. The combination has brought my cholesterol to the level that my cardiologist is happy with. My question is ... I have noticed a marked increase in ankle, foot, and leg swelling. It’s not caused by clots. Has anyone noticed the same symptoms while taking this drug."

• Big...
• Taken for 1 to 6 months
• March 28, 2021

For High Cholesterol "Had my first heart attack at 41yrs old had 4 more ended up with 2 open heart bypass surgery’s my cholesterol was off the chart 80 mg of statins did little to nothing. Repatha was prescribed 4 days after the first injection I was bed ridden for 5 days, hands, hips, neck, shoulder, lower back and knees all frozen, I couldn’t move without pain. Was switched to Praluent and worse effects. I’ve been in construction for 40 years and now I can’t provide for my family But my numbers have never been better but I will never inject again"

• EDB
• Taken for 1 to 6 months
• November 23, 2017

For High Cholesterol "I posted here in Aug stating that due to pain in my legs, fatigue, backache etc I had stopped this med. On a recheck w/doc in Sept I found that my chol had risen to 410! So rebound was terrible; double what it was pre-praluent! I am now back on 75 mg and will be rechecked in Dec. I am already experiencing nasal/mucous issues and some back pain and fatigue altho not as bad as when on 150 mg. What I'm wondering is if anyone out there knows if this can cause long term severe problems and has anyone talked to their doc about these side effects and if so what were their comments please."

• Neutr...
• Taken for 1 to 6 months
• October 9, 2019

For High Cholesterol "3rd month at 150mg/month to 300mg/month. Some side effects sore muscles joints for a day or two. Nothing too bad see what happens after increase. When on Statins there is no sore muscles joints for a day or two it's all the time. This drug is much better. Going to once a month dosing so am only sore or sick 2 or 3 days out of the month. Not a bad trade off if you ask me."

• Beav
• Taken for 1 to 6 months
• November 17, 2019

For High Cholesterol "66 yrs old, female, active tennis and daily walking; diagnosed heart disease but no symptoms. Can’t tolerate statins due to fatigue , memory, muscle issues. I’m on the bimonthly 75 mg Praluent for last three months. The shot is a sharp sting. The first week my legs ached really badly for 3 nites, couldn’t sleep , but that has diminished. Now after the shot , by the 3 day my legs are tired at nite, but It’s liveable. My chol numbers dropped dramatically from 350 (With HDL at only 50 a year ago). Now HDL is 127 and LDL is 60! Got much lowers and It Reversed. Great ratio. BUT liver enzymes are way up AST (was 26 to 130 now) and ASL up! But I had just returned from a cruise of heavy eating and drinking. So, now I cut out my nightly glass of wine completely, and will get a new blood test in a month."

• Lee
• Taken for 1 to 2 years
• April 9, 2019

For High Cholesterol, Familial Heterozygous "Have had no problems in 18 months. First time in adult life with normal cholesterol Had stent/ minor heart attack almost two years ago. Now have some neuropathy in hands and feet. Has anyone else had this problem?"

• Anonymous
• Taken for 1 to 6 months
• November 30, 2022

For High Cholesterol "Like so many other patients I had unfortunately side effects too. Muscle pain, leg, arms, even feet and neck pain. Worst, my hands are really hurting me, getting cramps, special at nights, now way to sleep properly. I just took medication for only 3 month..... Right now I am taking nothing to get rid of all these side effects. I hope it will be better, I don't know what will come next. After all these readings I get the idea that all the patients using these drugs are "guinea pigs" to try out this medication. It is very expensive and costs the health system a lot of money. Why is this drug still on the market....? I feel with anyone of you out there and hope one day you will be pain free again."

• larry...
• Taken for 1 to 6 months
• July 17, 2017

For High Cholesterol "I no luck with statins, Dr. put me on praluent (3.5 mo.) I have had 1 heart attack resulting with 1 stent before I started Praluent. I also have torticollis in my neck and buldge discs in back which I am treated for, but since I started Praluent seems like my symptoms are worse. My neck , back, and legs hurt. 2 weeks ago I thought I was having another heart attack, went to hospital ER pain eased and EKG came back normal, possible side effect? I am thinking about taking myself off Praluent, I am tired of feeling like garbage . I'm a 67 year old male ,"

• Omega
• Taken for 1 to 2 years
• November 5, 2020

For High Cholesterol, Familial Heterozygous "2 years following a massive heart attack and have been injecting praluent since. Twice a month at 75mg. LDL has dropped from 130 to 19! I have had no side effects. A little bleeding from injection site. Elequis, Plavix and Aspirin cause that. I tried to take statins since 2005 with first heart heart diagnosis, no joy on the numbers, just muscle pain. I was a vegan for 7 years and nothing helped until Praluent."

• Allan
• Taken for 1 to 6 months
• October 7, 2021

For High Cholesterol "Hi Just discovered this site, and reading through some of the reviews I now realise that I am not alone with all my negative thoughts with taking Praluent. I had heart bypass 2nd April 2020, and have been injecting Praluent last 4-5 months I have just had bloods taken by doctors to find out what is wrong with me I get results next week, and it is my intention to stop taking it immediately I do not recommend Praluent to anyone. Best to overhaul diet if needed, but do not take this drug. I have multiple issues with it. Everyone, please stop taking this drug, it is not safe. It might reduce your cholesterol, but at what cost to your general health. Stop eating red meat, fats, sugars, carbs, cakes etc etc, instead Take care Allan Scotland (54 yrs)"

• Rob
• Taken for 1 to 6 months
• May 14, 2019

For High Cholesterol, Familial Heterozygous "I am 42, Cabgx3. I had a Triple bypass graft in December of 2018. My total cholesterol was running between 450 and as high as 640 before. I’m 6’1 and 215 lbs. I am Active and eat healthy. 34” waist. No red meat or pork since surgery. I have never been able to tolerate Statins. They absolutely kick my butt. Since surgery I have been taking 150mg injections of praluent every 2 weeks with ZERO side effects. I’m on at least my 10 or 12 th injection and my cardiologist has yet to recheck my cholesterol. Surgeon said with my cholesterol history if this drug doesn’t work for me then I’d see him again in about 4 years. Lol. Hopefully that’s not the case. I’ll update when I get my levels checked next visit but for now I can report NO Side effects."

• Gaige
• January 25, 2020

For High Cholesterol "Hello I just got approved to use Praluent . I've had it for 4 days now. I'm too nervous to do the injection. So I've been reading all the comments that are helpful. The question I'm looking for does anyone know the size of the needle pls as I'm horrified of all needles pls???"

• chevy...
• October 26, 2015

For High Cholesterol "I have more frequent bowel movements but not diarrhea. My total cholesterol fell from 365 to 174. My HDL only decreased minimally from 42 to 37. My most interesting side effect is that I have had a tremendous increase in libido. I'm on testosterone replacement and about 8 meds for my heart disease and had minimal to moderate sex drive for about 5 years. There have been no changes in my meds or anything else except for the addition of Praluent. I am a 65 year old male."

• Mike...
• Taken for 1 to 2 years
• February 28, 2020

For High Cholesterol "I'm a 73 year old man. I had a heart attack 3 years ago at which time my LDL was 250mg. My cardio doctor put me on 40 milligrams of Atorvastatin (Lipitor) daily which lowered my LDL down to 125mg which was not low enough. He started me on Praluent 75mg painless injections in my upper legs once every two weeks that lowered my LDL to a very low 25 mg. after taking it for only two months with no side effects. I hope the price doesn't skyrocket so I can continue taking it til I die someday. I never thought I would get my LDL down to 25. It's unbeleivable. I hope it keeps me from having another painful heart attack. I'm told that Repatha and Praluent are about the same medicine."

• Bonita
• Taken for 1 to 6 months
• May 4, 2020

For High Cholesterol, Familial Heterozygous "I have high cholesterol all my life . All statins give me side effects . I got approved for this injection praluent . I am 65 and I also have lung issues that comes with constant cough plus pain in my body . I was reading the side effects of this drug and could get influenza , pain, cough etc I was looking for to this drug but now that I have I am having second thoughts . Any input in this ? "

• James...
• Taken for 2 to 5 years
• March 15, 2019

For High Cholesterol, Familial Heterozygous "I cannot tolerate statins so I've been taking Praluent for a few years and my bad cholesterol is way down and my good cholesterol is up to an acceptable level. But know I am thinking the praluent side effect is body pain and aches as for about the past six months I have been experiencing somewhat severe whole body pain. I feel better if I take Norco or Tramadol which I use for back pain, but on advice of my cardiologist I skipped the last Praluent dose to see if I feel any better. Praluent has a half-life of 17-20 days so I figure I'll need to wait at least 40 days to see if I feel better. I sure hope the Praluent is not the cause because it's keeping me alive. I'm 66 and my father died at age 57 from a heart attack. For me the only solution might be to increase my pain meds. I already have two completely clogged heart arteries so I need to do something to keep my liver from making too much cholesterol. Changing my diet did nothing."

• PEano
• Taken for 1 to 6 months
• May 1, 2020

For High Cholesterol "I started taking Praluent in January 2020. A few weeks in I had an awful UTI. Never ever had one before. It was miserable. Then six weeks later had another UTI. Only thing new was the Praluent. I started looking into the side effects and see that was a highlighted side effect. As I read more on this drug I see it may be causing the fatigue and pain in my lower back and pelvic area. I told my doctor I wasn’t going to continue. This was a last option as I have severe side effects from everything else we have tried. I did have blood work the other day and my numbers were lower but triglycerides were still high."

• Love
• Taken for less than 1 month
• March 24, 2018

For High Cholesterol "I am a 64yr old female. I did my first shot yesterday. Had to go to ER with very high bp, rapid hear bears, swollen eye lids, jittery, head and neck pain, itching, red skin. It was a negative experience"

• Diane
• Taken for 1 to 2 years
• April 11, 2024

For High Cholesterol "I’ve been on Praluent for over 2 years and have not had any side effects. I take the injection every 2 weeks, and all cholesterol levels are very good. If I had read all of these negative comments before using this medicine, I would’ve been petrified to try it."

• debbie
• Taken for 1 to 2 years
• December 12, 2022

For High Cholesterol, Familial Heterozygous "It is now some time since I gave feedback on the Praluent. I became extremely ill and discontinued it off my own bat because we were under lockdown and could get any help. Although the episodes finished I am, nevertheless, still struggling with the effects and am beginning to believe that I shall never go back to who I was before Praluent. The consultant, reluctantly, admitted that there were 'issues' with the product but I don't see that it has been taken off the market. Where can I go for help? Do we put up with being treated like guinea pigs and then abandoned when things go wrong?"

• JJ2905
• Taken for 1 to 6 months
• April 8, 2018

For High Cholesterol "I have been on this drug for 3 mo. Everytime I inject---for 36 hours I get leg pain and hand cramps and feel very tired. I am unable to sleep due to the leg pain and both hands have severe spasms. Joints seem to be getting worse with movement in tennis and pickle ball . I am going to see my doctor and stop this medication. Will have to do diet alone because all statins cause body spasms and cramps"

• Frmrb...
• July 17, 2016

For High Cholesterol, Familial Homozygous "After one injection I experienced swelling of hands and feet. My blood pressure elevated by more than 50 #. Praulent researchers said I had an autoimmune reaction and that it all would pass as the Praulent left my system. After 8 months I still have the High blood pressure. I am currently being checked for Vasculitis as the result of my autoimmune reaction."