Generic Name: Allopurinol Tablets (al oh PURE i nole)
Brand Name: Zyloprim
Medically reviewed by Drugs.com. Last updated on Feb 13, 2019.
Uses of Zyloprim:
- It is used to lower uric acid in the blood.
- It is used to prevent high uric acid levels during chemo.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Zyloprim?
- If you have an allergy to allopurinol or any other part of Zyloprim (allopurinol tablets).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Zyloprim (allopurinol tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Zyloprim?
- Tell all of your health care providers that you take Zyloprim (allopurinol tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how Zyloprim (allopurinol tablets) affects you.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking Zyloprim (allopurinol tablets) with your other drugs.
- Follow the diet and workout plan that your doctor told you about.
- A very bad and sometimes deadly reaction has happened with Zyloprim (allopurinol tablets). Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. Talk with the doctor.
- It may take several weeks to see the full effects.
- The chance of gout attacks may be higher for a few months after you start taking Zyloprim (allopurinol tablets). Do not stop taking Zyloprim (allopurinol tablets). You may be given other drugs to help you keep from getting gout attacks. Talk with your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Zyloprim (allopurinol tablets) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Zyloprim) best taken?
Use Zyloprim (allopurinol tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take after meals.
- To gain the most benefit, do not miss doses.
- Keep taking Zyloprim (allopurinol tablets) as you have been told by your doctor or other health care provider, even if you feel well.
- Keep taking Zyloprim (allopurinol tablets) even if you are having a gout attack.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Pain when passing urine.
- Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.
- Eye irritation.
- Change in eyesight.
- Joint pain that is new or worse.
- Swollen gland.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Chest pain or pressure.
- Liver problems have happened with Zyloprim (allopurinol tablets). Sometimes, liver problems have not gone back to normal after Zyloprim (allopurinol tablets) was stopped. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Low blood cell counts have happened with Zyloprim (allopurinol tablets). Most of the time, this happened in people who were also taking other drugs that can cause low blood cell counts. Call your doctor right away if you have any signs of infection like fever, chills, or sore throat; any unexplained bruising or bleeding; or you feel very tired or weak.
What are some other side effects of Zyloprim?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Zyloprim?
- Store at room temperature.
- Protect tablets from light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Zyloprim (allopurinol tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Zyloprim (allopurinol)
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- Drug class: antigout agents
Other brands: Aloprim