Generic Name: Rivaroxaban (15 mg and 20 mg) (RIV a ROX a ban)
Brand Name: Xarelto
Medically reviewed on May 2, 2018
- People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when already on this drug. This bleeding rarely happens, but can lead to not being able to move body (paralysis) long-term or paralysis that will not go away. The risk is raised in people who have problems with their spine, a certain type of epidural catheter, or have had spinal surgery. The risk is also raised in people who take any other drugs that may affect how the blood clots like blood-thinner drugs (like warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs). Talk with the doctor.
- Tell your doctor you use Xarelto (rivaroxaban (15 mg and 20 mg)) before you have a spinal or epidural procedure. Call your doctor right away if you have any signs of nerve problems like back pain, numbness or tingling, muscle weakness, paralysis, or loss of bladder or bowel control.
- Talk with your doctor if you have recently had or will be having a spinal or epidural procedure. Some time may need to pass between the use of Xarelto (rivaroxaban (15 mg and 20 mg)) and your procedure. Talk with your doctor.
- Stopping Xarelto (rivaroxaban (15 mg and 20 mg)) before you are supposed to may raise the chance of blood clots. Do not stop taking Xarelto (rivaroxaban (15 mg and 20 mg)) without talking to your doctor.
Uses of Xarelto:
- It is used to thin the blood so that clots will not form.
- It is used to treat blood clots.
What do I need to tell my doctor BEFORE I take Xarelto?
- If you have an allergy to rivaroxaban or any other part of Xarelto (rivaroxaban (15 mg and 20 mg)).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have bleeding problems.
- If you have any of these health problems: Kidney disease or liver disease.
- If you have had a heart valve replaced.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with Xarelto (rivaroxaban (15 mg and 20 mg)), like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with Xarelto (rivaroxaban (15 mg and 20 mg)).
- If you are taking St. John's wort. Do not take St. John's wort with Xarelto (rivaroxaban (15 mg and 20 mg)). This medicine may not work as well.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with Xarelto (rivaroxaban (15 mg and 20 mg)).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Xarelto (rivaroxaban (15 mg and 20 mg)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Xarelto?
- Tell all of your health care providers that you take Xarelto (rivaroxaban (15 mg and 20 mg)). This includes your doctors, nurses, pharmacists, and dentists.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Very bad and sometimes deadly bleeding problems have happened with Xarelto (rivaroxaban (15 mg and 20 mg)). Talk with the doctor.
- If you fall or hurt yourself, or if you hit your head, call your doctor right away. Talk with your doctor even if you feel fine.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you are 65 or older, use Xarelto (rivaroxaban (15 mg and 20 mg)) with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Xarelto (rivaroxaban (15 mg and 20 mg)) while you are pregnant.
How is this medicine (Xarelto) best taken?
Use Xarelto (rivaroxaban (15 mg and 20 mg)) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take Xarelto (rivaroxaban (15 mg and 20 mg)) with food.
- If you cannot swallow tablets, the tablet may be crushed and mixed with applesauce. Take within 4 hours of mixing.
- Eat some food right after taking a crushed tablet.
- Those who have feeding tubes may also use the 15 mg or 20 mg tablets. Crush tablets and mix with 50 mL of water. Give within 4 hours of mixing. Give enteral feeding right after giving dose.
- To gain the most benefit, do not miss doses.
- Keep taking Xarelto (rivaroxaban (15 mg and 20 mg)) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
15 mg twice daily dosing:
- Take missed dose right away to make sure you get 30 mg in one day. You may take 2 tablets at the same time. Then go back to your normal times the next day.
All other dosing:
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Very bad dizziness or passing out.
- A burning, numbness, or tingling feeling that is not normal.
- Muscle weakness.
- Feeling confused.
- Very bad headache.
- Feeling very tired or weak.
- Pain, swelling, or new drainage at wound sites.
What are some other side effects of Xarelto?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Xarelto?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Xarelto (rivaroxaban (15 mg and 20 mg)) is refilled. If you have any questions about Xarelto (rivaroxaban (15 mg and 20 mg)), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about rivaroxaban
- Rivaroxaban Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 136 Reviews – Add your own review/rating
- Drug class: factor Xa inhibitors
Other brands: Xarelto