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Romosozumab

Generic Name: Romosozumab (ROE moe SOZ ue mab)
Brand Name: Evenity

Medically reviewed by Drugs.com. Last updated on Jun 18, 2019.

Warning

  • This medicine may raise the risk of heart attack, stroke, and death from heart or blood vessel disease. Do not take romosozumab if you have had a heart attack or stroke in the past year. If you have ever had a heart attack, stroke, or other heart or blood vessel problems, talk with your doctor.
  • Call your doctor or get medical help right away if you have signs of heart attack or stroke. This includes chest pain or pressure, shortness of breath, dizziness or passing out, severe headache, weakness on 1 side of the body, trouble speaking or thinking, change in eyesight or balance, or drooping on 1 side of the face.

Uses of Romosozumab:

What do I need to tell my doctor BEFORE I take Romosozumab?

  • If you have an allergy to romosozumab or any part of romosozumab.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have low calcium levels.
  • If you are pregnant or breast-feeding. This medicine is not approved for use in women who are pregnant or breast-feeding.

This is not a list of all drugs or health problems that interact with romosozumab.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take romosozumab with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Romosozumab?

  • Tell all of your health care providers that you take romosozumab. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Take calcium and vitamin D as you were told by your doctor.
  • Have a dental exam before starting romosozumab.
  • Take good care of your teeth. See a dentist often.
  • This medicine may raise the chance of a broken leg. Talk with the doctor.
  • Have a bone density test as you have been told by your doctor. Talk with your doctor.

How is this medicine (Romosozumab) best taken?

Use romosozumab as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into the fatty part of the skin on the top of the thigh, belly area, or upper arm.
  • Your doctor will give romosozumab.

What do I do if I miss a dose?

  • If shot is missed, call your doctor for a new time.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of low calcium levels like muscle cramps or spasms, numbness and tingling, or seizures.
  • Any new or strange groin, hip, or thigh pain.
  • This medicine may cause jawbone problems. The risk may be higher with longer use, cancer, dental problems, ill-fitting dentures, anemia, blood clotting problems, or infection. It may also be higher if you have dental work, chemo, radiation, or take other drugs that may cause jawbone problems. Many drugs can do this. Talk with your doctor if any of these apply to you, or if you have questions. Call your doctor right away if you have jaw swelling or pain.

What are some other side effects of Romosozumab?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Romosozumab?

  • Store in a refrigerator. Do not freeze.
  • Store in the carton to protect from light.
  • Do not shake.
  • If needed, you may store at room temperature for up to 30 days. If stored at room temperature and not used within 30 days, throw romosozumab away.
  • Protect from heat.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time romosozumab is refilled. If you have any questions about romosozumab, please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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