Romosozumab User Reviews & Ratings

• Liz
• Taken for 6 months to 1 year
• December 10, 2022

Evenity (romosozumab) for Osteoporosis "I did have gain in the left hip & spine, but needed the support in the right hip. The right hip went from -2.7 to -2.8. All I went through & had no gain. From the second month I had side effects. First was stomach pains(4 tests & 3 Doctors), next a terrible cough & dry throat (continue to have trouble with this one), fingernails peeled off & still can’t get them to grow and last was face & neck rash with three trips to dermatologist. Wish I had never started this & would never recommend it."

• Joanne
• Taken for 1 to 6 months
• June 28, 2023

Evenity (romosozumab) for Osteoporosis "My T score was -3, so I was advised by my rheumatologist to start Evenity. I'm 70 years old and pretty active. This drug took me down in less than a week. I experienced fatigue for two days, but that dissipated. Unfortunately, my blood pressure went through the roof, and I still have bad neck pain. I asked my rheumatologist if she's seen other patients with side effects and she said no. I find that extremely hard to believe. I noticed some have had a few to no side effects. However, it's hard to ignore all of the negative reviews here. I told my doctor today I was not going to continue. She wants to put me on Prolia, probably the same side effects. I'm stuck between a rock and a hard place. I wish there were some other alternative that was not as risky. Good luck to all."

• Laura
• Taken for 6 months to 1 year
• April 2, 2023

Evenity (romosozumab) for Osteoporosis "Had 11 months of injections. Injections aren't comfortable but tolerable. Sometimes I would get a headache but by months 8 or 9, I was noticing aching in my hands, wrists, elbows, hips, etc. As I was so close to the 12 months I continued through the 11 months. Didn't have the last injections and haven't had an injection since the beginning of February. I have always been active by walking, mountain biking, skiing, hiking, etc., and watching my diet, supplements, etc. I now feel like I have arthritis. All bloodwork is perfect, DEXA improved in the spine by 49%, pretty impressive, and where I had osteoporosis in three sites I only have osteoporosis in my hip. But, I am so stiff early in the morning, and dull aching wakes me up at night sometimes. I am hopeful, prayerful, that these side effects will go away. Am switching now to Fosomax or Reclast but the Evenity journey is one to keep an eye on. I kind of wish I had stopped sooner as I believe, not 100% certain, that the most benefit is in the first 6 mos. I'm 67."

• Huge...
• Taken for 1 to 6 months
• February 13, 2023

Evenity (romosozumab) for Osteoporosis "I am 68. I took my first Evenity shots in October 2022 and my last in December 2022. Since October, I have had dyspnea, dizziness, and lightheadedness. I can hardly be in a store for more than 10 minutes without feeling as if I will faint. Because of fatigue and weakness, household tasks are difficult. I move much more slowly. Now with dysphagia and anorexia, eating is difficult. Although never painful before, the joints in my hands, fingers, and toes are stiff and painful. Additionally, I developed cramping in those areas. The pain in my hips, upper thighs, neck, and shoulders are poorly responsive to all pain medications. There was an exacerbation of pain in several old areas of injury which had not been painful for decades. And now I have intermittent pain in my eyes and an annoying twitch in one that will not subside. After that first shot, it was as if someone flipped on a switch with all these symptoms. My concern is they will not go away for a long time, if ever. Evenity was a huge mistake!"

• Dogwo...
• Taken for 1 to 6 months
• July 29, 2022

Evenity (romosozumab) for Osteoporosis "After the 6th injection my GFR lab results fell from 97 to 55 indicating damage or issues with my kidneys. Vitamin D went from 87 to 155. I have been told but other doctors that 150 is toxic level for vitamin D. I have had continued pain, kidney issues, lab results in several areas very erratic. I have had a difficult time getting the doctor to order lab tests. The doctor continues to tell me to hold on until the year is up, I think he is getting a payoff to keep patients on this drug by Evenity! I have scheduled a second opinion review with another doctor/endocrenologist and urologist. Will report back in a month or two. I do not recommend taking this drug."

• Deirdre
• Taken for 6 months to 1 year
• April 4, 2023

Evenity (romosozumab) for Osteoporosis "I started Evenity in April 2022 and just completed the last dose in March 2023. My t-score before starting this medication was very poor at -3.5. I had NO side effects from this medication. I actually started feeling better after the first dose with much less pain from a previously broken hip due to severe osteoporosis. I’m optimistic about a good amount of improvement in my bone density because I have felt so much better. I recommend this medication. I think it’s the best treatment on the market."

• Anonymous
• Taken for 1 to 6 months
• February 7, 2023

Evenity (romosozumab) for Osteoporosis "My numbers: -4.2 spine, -1.8 hips. Within a week of starting this drug, I had a gradual onset of pain in the groin, hip and sacral joint in my right leg. This got progressively worse and by the end of the month I was limping. After the 2nd month injection, the pain increased even more, with severe pain pain and stiffness in the hip and I struggled to climb stairs until eventually could only put weight on left leg. I have never had problems with my hips and was now struggling with the simple activities of daily life. I was horrified at the increasing loss of mobility and shocked at being encouraged to continue with this drug, as my endocrinologist said “it is building bone” but what use is that if my mobility so severely impaired? By my third injection, I was struggling to walk and my treatment was discontinued. I have had a gradual improvement over 4 weeks and can now walk and climb stairs, but still have currently have hip pain. I absolutely do not recommend this drug."

• Tommie
• Taken for 1 to 6 months
• March 20, 2023

Evenity (romosozumab) for Osteoporosis "I took Evenity after an endocrinologist with my immunologist’s blessing decided it would help with 3.2 Osteoporosis after a hip stress fracture. It was the worst decision to listen to them, it’s poison! Sick after the first shot but wasn’t sure if it was the flu or not, so continued taking it. After 2 shots started the diarrhea and swelling in my throat and mouth. After the 3rd shot my jaw started tweeking, moving on it’s own. My upper and lower back teeth hurt, I was biting my mouth, tongue and cheeks while eating AND in the middle of the night. Headaches, continued flu like symptoms, added fatigue, insomnia, and overall feeling crappy. I finally took myself off Evenity after the 6th shot. (Prescribed for 12 months) I now have a twisted jaw where my teeth no longer match up and can only eat on my left side teeth, horrible. The doc prescribing it and my PCP never mentioned the horrible side effects in their notes. Saw orthodontist, bite is completely off."

• calired
• Taken for 6 months to 1 year
• October 29, 2022

Evenity (romosozumab) for Osteoporosis "I had my 10th Evenity injection Oct 26th. Two more to go. I had very little in side effects throughout the past 10 months of injections. Some slight joint pain in wrists and some fatigue on occasion. Took blood tests throughout every 3 months. Vitamin D and calcium levels remained steady and normal. I will see how much success in bone density improvement occurred in January 2023 when I will take my next density test. But as it stands today, I have had no problems with this drug."

• BirdB...
• December 12, 2022

Evenity (romosozumab) for Osteoporosis "I have completed 12 months. I’m on constant pain in my arms legs groin. Hard time walking. I could walk and only had backups in when I started. My body has compressed and I’ve now got a big belly, even though I’ve not gained weight. All I can say is the Dexascan better improve! I’m having it in January 2023. Very unhappy and on antidepressant."

• Shrtg...
• Taken for 6 months to 1 year
• February 10, 2023

Evenity (romosozumab) for Osteoporosis "Just completed round #9 of 12 injections. Things potential patients should know: 1) The injections are painful...think cortisone joint injection painful, but not quite. 2) Expect post-injection swelling, sensitivity, itching, etc. 3) Expect to have some degree of generalized malaise in the days following your injections. After the first round, I, personally, felt like I had the flu...minus any fever, nausea, or vomiting. Severe headache and body aches. Subsequent injections brought similar after-effects, though to a somewhat lesser degree. With every visit, you are asked the same questions about your general health-any new/planned dental surgery (osteonecrosis of the jawbone), stroke/heart attack, serious illness, or infection which makes me more than a little concerned about the long-lasting negative impacts on my health. At my most recent visit with the doctor, he indicated the best bone density improvement will only be about 10%. In my opinion, that's not much considering all the pain and misery I feel while taking it."

• Terri
• Taken for 6 months to 1 year
• March 23, 2023

Evenity (romosozumab) for Osteoporosis "I have been on this medication for six months, not yet had another bone density test. I consider myself very active before going on this medication but now I have generalized joint pain and difficulty getting up from a sitting or standing position without pain. My pain now is in my lower back. I am not happy with the Evenity helpline all they do is just take your information. I hope I get better results on my bone density and I hope this joint pain goes away upon completion of this drug."

• EV 12...
• Taken for 6 months to 1 year
• October 18, 2022

Evenity (romosozumab) for Osteoporosis "Just finished 12 months of Evenity shots. During this period I took Prempro estrogen, a multivitamin, and calcium with vitamin D. I also walked 2 miles a day, did push ups, sit-ups and used light weights. Starting T scores were: Hip -1.6 and Lumbar -2.5. Ending T scores were: Hip -1.8 and Lumbar -1.9. Lumbar bone density was significantly better, however Hip bone density got worse."

• Garde...
• Taken for 6 months to 1 year
• March 6, 2023

Evenity (romosozumab) for Osteoporosis "Worked well for me. The only side effect I experienced was soreness at the injection sites for two days post-injection. I received Evinity because I had severe spinal bone loss from taking prednisone 20mg daily for 5 months. This was my first flare of rheumatoid arthritis. I had two severe thoracic vertebrae fractures in 3 months. After my year on Evinity, my osteoporosis has improved."

• Ellen
• Taken for 6 months to 1 year
• April 2, 2023

Evenity (romosozumab) for Osteoporosis "Have completed six of twelve injections. As mentioned in other reviews, I have experienced flu like symptoms the day after each series of injections. Recent CMP shows BUN/Creatine Ratio doubled in past 6 months! Calcium and Vit D fine. For past 2 months have been dealing with persistent arrhythmias. In process of complete cardiac work up. Am trying to understand if/how Evenity impacts heart functioning. Conflicting research on romosozumab and cardiovascular risks. Questioning whether I will complete six more months of injections."

• AGM
• Taken for 6 months to 1 year
• April 14, 2023

Evenity (romosozumab) for Osteoporosis "I have taken 11 courses of Evenity thus far...and every time I have had pain/swelling/itching at the injection site, headaches, body aches, lethargy, and trouble sleeping in the days following the injection...though admittedly, the ill effects are not as severe now as in the early days of the treatment. However, I am concerned about the long-term after-effects, mostly issues with my teeth/jawbone. While I have been closely monitored by my dentist and all appears well thus far, it's still a worry. And too, the potential for bone build/improvement is minimal at best--10% according to my doctor. Seems like a lot of misery to go through for such a little bit of potential improvement. My doctor also recommended I move to another injectable medication once I finish with Evenity, but they ALL carry the same terrible potential risks, so I declined. I hope to have some bone density improvement, but honestly, I do not expect much."

• celam
• Taken for 1 to 2 years
• September 6, 2023

Evenity (romosozumab) for Osteoporosis "BEST Osteo med ever!!! I was on Fosamax which caused severe stomach and kidney issues. Then was put on Actonel which caused severe inflammation of my breast bone and sternum. Took forever to get Evenity approved because I was only 45- had ovarian Cancer in my 20s so went thru premature menopause and with having cancer I couldn’t do hormone replacement so 1st dexa in 2016 after I broke a rib when my husband picked me up in a bear hug showed osteopenia (-2.1) and tried the mentioned options and in 2019 Tscore went to -2.9 drs tried getting other meds approved but insurance just saw my age and denied. The Covid delayed further options…. Found a new rheumatologist last year and she got Evenity approved in 3 weeks and with the additional co pay card from the manufacturer I was able to afford it. Last dose was in July and New Dexa had bones in normal range!!!!!!!!!"

• barbi...
• Taken for 1 to 6 months
• September 21, 2023

Evenity (romosozumab) for Osteoporosis "I had my second injection on September 20, 2023. I had no side effects. I was very skeptical about taking it after I was reading about so many people that were having so many side effects. The injection did not even hurt. I am so glad that I started. This just goes to show that everybody is different."

• 1even...
• Taken for 6 months to 1 year
• February 6, 2024

Evenity (romosozumab) for Osteoporosis "In the beginning I had no side effects. Then, I developed pain in my thighs and arms, knees and hands. The last 4 months I had severe headaches and very strong whole body pain. This felt like my nerve endings were firing at the same time. Each month the pain increased to the point where I could not sleep for several days. I stopped taking it 3 months ago and still have episodes once in awhile. I told my doctor but he totally dismissed it. I was told by my doctor that if I stopped taking it, my bones would revert back to the previous state. I was not told that until I stopped the shots. These are just some of my side effects. There were more."

• Linda...
• Taken for 6 months to 1 year
• July 12, 2023

Evenity (romosozumab) for Osteoporosis "I'm going to be getting my 9th shot and have had little or no problems. The first 4 months I had headaches for a few hours, but a Tylenol took care of it. Now, I take a Tylenol before I get the 2 shots. Some tenderness at the shot site, but no different from a flu shot. I'll have a bone scan in October, it's July now. I feel positive, as my T score was -4 after too many years of Fosamax. I'm staying positive and don't concentrate on the 'what if'. I had to try something. I continue to walk 2 miles every day and try to lift weights. I'm 75 now, so feel positive that I'm doing the best I can."

• Sophie
• Taken for 6 months to 1 year
• June 13, 2023

Evenity (romosozumab) for Osteoporosis "Started Evenity April 2022. Stopped after 2 injections due to jaw pain and increased headaches. I have migraine and after taking Evenity my migraines increased in intensity and frequency by 70 %. Started again last month nearly a year later and my migraine are increasing again. Also broke out in large very painful canker sore 2 times, on roof of my mouth which lasted 2 weeks, with flu like symptoms and significant fatigue. Also dealing with neck pain every day. Will be discussing stopping Evenity this week."

• DLHH
• Taken for 1 to 6 months
• January 28, 2023

Evenity (romosozumab) for Osteoporosis "I had injections for 5 months. Not bad at first but the last 2 months had to take pain pills for the all-over joint pain in my neck, wrists, back and feet. My T score to begin with was -3.8. Haven't had it redone but switching to a different medication"

• PDE
• Taken for 1 to 6 months
• June 3, 2023

Evenity (romosozumab) for Osteoporosis "I had injections from November through April and had to stop due to increasing high blood pressure. That is not listed as a side effect however, it is closely related to some of the listed side effects. I still don’t have my blood pressure under control and it is June. I wonder how long I’ll suffer from this side effect."

• Diane
• Taken for 1 to 6 months
• August 23, 2023

Evenity (romosozumab) for Osteoporosis "I have only had two injections of Evenity. However, the first two days after I have it, I am in bed with flu-like symptoms and a bad headache. I had a total hip replacement in May 2023, and my surgeon said my bones were very bad, even though I have been on Prolia for 10 years. That's why they want me to try Evenity. I am having severe groin pain and hip pain, along with my hair falling out really bad. I will continue for a few more months to see if some of these conditions stop."

• Posit...
• Taken for 1 to 2 years
• June 24, 2023

Evenity (romosozumab) for Osteoporosis "I'm a 72-year-old women who just finished the 12-month Evenity program, and I am currently transitioning to Prolia. My experience has been positive, with no noticeable side effects. From my blood work, it appears to have been working as described. My next bone scan will be a year from now, so I will not know what changes have occurred with my bone density until then."