Generic Name: ingenol (IN-je-nol)
Brand Name: Picato
Picato is used for:
Treating actinic keratoses. It may also be used for other conditions as determined by your doctor.
Picato treats actinic keratoses by causing cell death. Exactly how it causes cell death is not known.
Do NOT use Picato if:
- you are allergic to any ingredient in Picato
Contact your doctor or health care provider right away if any of these apply to you.
Before using Picato:
Some medical conditions may interact with Picato. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have other skin problems or a sunburn in the treatment area
- if you are being treated or have been treated for actinic keratoses with other medicines or surgery. You should not use Picato until your skin has healed from other treatments
Some MEDICINES MAY INTERACT with Picato. Because little, if any, of Picato is absorbed into the blood, the risk of it interacting with another medicine is low.
Ask your health care provider if Picato may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Picato:
Use Picato as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Picato. Talk to your pharmacist if you have questions about this information.
- Picato is for external use only. Do not get it in your eyes, nose, vagina, or mouth. If you get Picato in your eyes, flush them with large amounts of water and seek medical care as soon as possible.
- Do not apply Picato to any area of the body other than the affected area.
- Do not apply Picato right after taking a shower or less than 2 hours before bedtime.
- Apply Picato to the affected area once each day. Use a new tube for each day of treatment.
- Squeeze Picato onto a fingertip. Use only enough medicine to cover the affected area, as directed by your doctor.
- Spread Picato evenly over only the affected skin area and allow it to dry for 15 minutes.
- Wash your hands immediately after using Picato, unless your hands are part of the treated area.
- Do not cover the treated area with bandages or other dressings after you have applied Picato.
- Avoid touching the treated area or doing activities that cause excessive sweating for 6 hours after applying Picato. After 6 hours, you may wash the treatment area with mild soap and water.
- Avoid transferring Picato to other areas or to another person after it has been applied.
- Only use a tube of Picato one time. Throw away any unused medicine that is left in the tube after use. Do not keep a tube that has been used for use at a later time. Throw away any used tubes in a trash container, away from children and pets.
- If you miss a dose of Picato, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Picato.
Important safety information:
- Eye problems, including severe eye pain, swelling or drooping eyelids, or swelling around the eyes, may occur if Picato gets in your eyes. Do not touch your eyes while you are applying Picato. Wash your hands well with soap and water after applying Picato. Do not allow the medicine on the treated area to come into contact with your eyes. If you get it in your eyes, flush them with large amounts of water and seek medical care as soon as possible.
- Skin reactions, such as mild redness, flaking or scaling, crusting, or swelling at the application site are common with the use of Picato. Tell your doctor right away if you develop blisters, pus, sores, ulcers, or severe redness, flaking or scaling, crusting, or swelling at the application site.
- Do NOT use for longer than prescribed without checking with your doctor.
- Do not use more of Picato than needed to cover the affected area. Using too much or using it too often or too long can increase your risk for a severe skin reaction or other side effects.
- Do not use other medicines or products on the treated area without first checking with your doctor.
- Picato may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
- Picato should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Picato while you are pregnant. It is not known if this medicine is found in breast milk after topical use. If you are or will be breast-feeding while you use Picato, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Picato:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Headache; mild pain, itching, irritation, redness, flaking or scaling, crusting, or swelling at the application site; nose and throat irritation.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blisters, pus, sores, or ulcers at the application site; severe redness, flaking or scaling, crusting, or swelling at the application site.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Picato:
Store Picato in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Picato out of the reach of children and away from pets.
- If you have any questions about Picato, please talk with your doctor, pharmacist, or other health care provider.
- Picato is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Picato or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Picato. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Picato. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Picato.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.