Generic Name: Norfloxacin (nor FLOKS a sin)
Brand Name: Noroxin
Medically reviewed on Sep 5, 2018
- This medicine may cause very bad side effects. These include irritated or torn tendons; nerve problems in the arms, hands, legs, or feet; and nervous system problems. These side effects can happen alone or at the same time. They can happen within hours to weeks after starting this drug. Some of these side effects may not go away, and may lead to disability or death. Talk with the doctor.
- The chance of irritated or torn tendons is greater in people over the age of 60; heart, kidney, or lung transplant patients; or people taking steroid drugs. Tendon problems can happen as long as several months after treatment. Call your doctor right away if you have pain, bruising, or swelling in the back of the ankle, shoulder, hand, or other joints. Call you doctor right away if you are not able to move or bear weight on a joint or if you hear or feel a snap or pop.
- Call your doctor right away if you have signs of nerve problems. These may include not being able to handle heat or cold; change in sense of touch; or burning, numbness, tingling, pain, or weakness in the arms, hands, legs, or feet.
- Call your doctor right away if you have signs of nervous system problems. These may include anxiety, bad dreams, trouble sleeping, change in eyesight, dizziness, feeling confused, feeling nervous or agitated, feeling restless, hallucinations (seeing or hearing things that are not there), new or worse behavior or mood changes like depression or thoughts of killing yourself, seizures, or very bad headaches.
- Do not take if you have myasthenia gravis. Very bad and sometimes deadly breathing problems have happened with norfloxacin in people who have myasthenia gravis.
- For some health problems, norfloxacin is only for use when other drugs cannot be used or have not worked. Talk with the doctor to be sure that the benefits of norfloxacin are more than the risks.
Uses of Norfloxacin:
- It is used to treat bacterial infections.
What do I need to tell my doctor BEFORE I take Norfloxacin?
For all patients taking norfloxacin:
- If you have an allergy to norfloxacin or any other part of norfloxacin.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Long QT on ECG, low magnesium levels, or low potassium levels.
- If you have ever had any of these health problems: Nerve problems or tendon problems.
- If you have had tendons get irritated or torn when taking norfloxacin or an alike drug in the past.
- If you are not able to pass urine.
- If you are taking probenecid.
- If you have been taking any drugs to treat a heartbeat that is not normal.
- If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If the patient is a child. This medicine is not approved for use in children.
This is not a list of all drugs or health problems that interact with norfloxacin.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take norfloxacin with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Norfloxacin?
- Tell all of your health care providers that you take norfloxacin. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how norfloxacin affects you.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
- Tell your doctor if you have signs of high or low blood sugar like breath that smells like fruit, dizziness, fast breathing, fast heartbeat, feeling confused, feeling sleepy, feeling weak, flushing, headache, more thirsty or hungry, passing urine more often, shaking, or sweating.
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking norfloxacin with your other drugs.
- Do not use longer than you have been told. A second infection may happen.
- Tell your doctor if you take a drug that has caffeine, or you eat or drink products that have caffeine, like tea, coffee, cola, or chocolate.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- Drink lots of noncaffeine liquids every day unless told to drink less liquid by your doctor.
- Be careful if you have G6PD deficiency. Anemia may happen.
- If you are over the age of 60, use norfloxacin with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using norfloxacin while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Norfloxacin) best taken?
Use norfloxacin as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take norfloxacin at the same time of day.
- Take on an empty stomach. Take 1 hour before or 2 hours after meals or having milk or other dairy products.
- Take with a full glass of water.
- Do not take dairy products, antacids, didanosine, multivitamins, minerals (calcium, iron, zinc, magnesium), or sucralfate within 2 hours of norfloxacin.
- To gain the most benefit, do not miss doses.
- Keep using norfloxacin as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Dizziness or passing out.
- Chest pain or pressure, a fast heartbeat, or passing out.
- A heartbeat that does not feel normal.
- Feeling very tired or weak.
- Shortness of breath.
- Any unexplained bruising or bleeding.
- Fever or chills.
- Ringing in ears.
- Trouble walking.
- Muscle pain or weakness.
- Vaginal itching or discharge.
- White patches in mouth.
- Very bad and sometimes deadly liver problems have happened with norfloxacin. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- It is common to have diarrhea when taking norfloxacin. Rarely, a very bad form of diarrhea called Clostridium difficile (C diff)–associated diarrhea (CDAD) may occur. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen while you are taking norfloxacin or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
What are some other side effects of Norfloxacin?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Feeling sleepy.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Norfloxacin?
- Store at room temperature.
- Keep lid tightly closed.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time norfloxacin is refilled. If you have any questions about norfloxacin, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about norfloxacin
- Norfloxacin Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- 3 Reviews
- Drug class: quinolones
- FDA Alerts (3)
Other brands: Noroxin