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Norepinephrine

Pronunciation

Generic Name: norepinephrine (NOR-ep-i-NEF-rin)
Brand Name: Levophed

Norepinephrine is used for:

Treating low blood pressure. It may also be used for other conditions as determined by your doctor.

Norepinephrine is a peripheral vasoconstrictor and an inotropic stimulator. It works by making the blood vessels narrower, which increases blood pressure. It also helps the heart work better.

Do NOT use norepinephrine if:

  • you are allergic to any ingredient in norepinephrine

Contact your doctor or health care provider right away if any of these apply to you.

Before using norepinephrine:

Some medical conditions may interact with norepinephrine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have blood vessel problems, blood clots, or thyroid problems

Some MEDICINES MAY INTERACT with norepinephrine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) or tricyclic antidepressants (eg, amitriptyline) because severe, long-lasting high blood pressure may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if norepinephrine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use norepinephrine:

Use norepinephrine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Norepinephrine is usually given as an infusion at your doctor's office, hospital, or clinic.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of norepinephrine, contact your doctor right away.

Ask your health care provider any questions you may have about how to use norepinephrine.

Important safety information:

  • Tell your doctor or dentist that you take norepinephrine before you receive any medical or dental care, emergency care, or surgery.
  • This product contains sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, talk with your doctor.
  • Norepinephrine may cause tissue damage if it leaks from the vein. Tell your doctor if you have any redness, burning, pain, swelling, or leaking of fluid where the medicine is going into your body.
  • Use norepinephrine with caution in the ELDERLY; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using norepinephrine while you are pregnant. Norepinephrine may be found in breast milk. If you are or will be breast-feeding while you use norepinephrine, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of norepinephrine:

All medicines may cause side effects, but many people have no, or minor side effects. No COMMON side effects have been reported with norepinephrine. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing); anxiety; change in skin color (eg, on the lips, nail beds, fingers, or toes); fast, slow, or irregular heartbeat; severe or persistent dizziness or headache.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of norepinephrine:

Norepinephrine is handled and stored by a health care provider. Keep norepinephrine out of the reach of children and away from pets.

General information:

  • If you have any questions about norepinephrine, please talk with your doctor, pharmacist, or other health care provider.
  • Norepinephrine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take norepinephrine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about norepinephrine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to norepinephrine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using norepinephrine.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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