Generic name: Naloxone Auto-Injection (nal OKS one)
Brand name: Evzio
Drug class: Antidotes
Medically reviewed by Drugs.com. Last updated on Jan 1, 2021.
Uses of Naloxone Auto-Injection:
- It is used to treat some overdoses.
What do I need to tell my doctor BEFORE I take Naloxone Auto-Injection?
- If you are allergic to naloxone auto-injection; any part of naloxone auto-injection; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take naloxone auto-injection with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Naloxone Auto-Injection?
- Tell all of your health care providers that you take naloxone auto-injection. This includes your doctors, nurses, pharmacists, and dentists.
- If you are addicted to pain drugs and are given naloxone auto-injection, you may have signs of withdrawal. Talk with your doctor.
- In infants younger than 4 weeks old who have been getting opioid drugs on a regular basis, sudden withdrawal may be life-threatening if not treated right away. Get medical help right away if your child has a seizure, is crying more than normal, or has increased reflexes.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
- If naloxone auto-injection is used during pregnancy, it may cause withdrawal in the unborn baby. A doctor will need to check on the unborn baby after naloxone auto-injection is used.
How is this medicine (Naloxone Auto-Injection) best taken?
Use naloxone auto-injection as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a muscle or into the fatty part of the skin.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Be sure you know how to use before an emergency happens. Read the package insert and instructions for use that come with naloxone auto-injection. If you have any questions about how to use naloxone auto-injection, talk with the doctor or pharmacist.
- Someone else may have to give naloxone auto-injection. Be sure others know where naloxone auto-injection is stored and how to give it if needed.
- Jab straight into the outer thigh as you have been told. This medicine may be given through clothes if needed. Inject and hold for as long as you were told.
- Do not use naloxone auto-injection if the solution changes color, is cloudy, or has particles. Get a new one.
- Each auto-injector has only 1 dose. If another dose is needed, you will need to use a second auto-injector.
- After using naloxone auto-injection, overdose symptoms may go away and come back. It is important to get medical help right away after using naloxone auto-injection.
- Do not use if naloxone auto-injection is out of date. Get a new one.
What do I do if I miss a dose?
- Get medical help right away.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Shortness of breath.
- Chest pain or pressure.
- Fast or abnormal heartbeat.
- A burning, numbness, or tingling feeling that is not normal.
- Feeling agitated.
- Mood changes.
- Hallucinations (seeing or hearing things that are not there).
- Sweating a lot.
What are some other side effects of Naloxone Auto-Injection?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Naloxone Auto-Injection?
- Store at room temperature. Do not freeze.
- Store in the case you were given.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about naloxone auto-injection, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
- What's the difference between naltrexone and naloxone?
- How long does naloxone block opiates?
- Will naloxone show up on a drug test?
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- How does naloxone work in an overdose?
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- How do you administer naloxone?
More about naloxone
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Compare Alternatives
- Pricing & Coupons
- 22 Reviews
- Drug class: antidotes
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.