Generic Name: Mifepristone Tablets 300 mg (MIF e PRIS tone)
Brand Name: Korlym
Medically reviewed on September 5, 2018
- Use in pregnant women will cause fetal loss.
- Do not take if you are pregnant. A pregnancy test will be done to show that you are NOT pregnant before starting Korlym (mifepristone tablets 300 mg). Use a type of birth control that is not hormone-based while taking Korlym (mifepristone tablets 300 mg) and for 1 month after stopping Korlym (mifepristone tablets 300 mg). Talk with your doctor.
- If Korlym (mifepristone tablets 300 mg) is stopped for more than 14 days, another pregnancy test will need to be done. Talk with your doctor.
Uses of Korlym:
- It is used to lower blood sugar in patients with Cushing's syndrome.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Korlym?
- If you have an allergy to mifepristone or any other part of Korlym (mifepristone tablets 300 mg).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are breast-feeding or plan to breast-feed.
- If you have any of these health problems: Change in the cells lining your uterus, endometrial cancer, or if you have ever had vaginal bleeding where the cause was not known.
- If you do not have Cushing's syndrome.
- If you are pregnant or may be pregnant. Do not take Korlym (mifepristone tablets 300 mg) if you are pregnant.
- If you have liver disease.
- If you have low potassium levels, talk with your doctor.
- If you must take a steroid drug like prednisone for other health problems.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with Korlym (mifepristone tablets 300 mg), like certain drugs that are used for high cholesterol, migraine headache, blocking the immune system, mood or mental problems, and pain. There are many drugs that must not be taken with Korlym (mifepristone tablets 300 mg).
This is not a list of all drugs or health problems that interact with Korlym (mifepristone tablets 300 mg).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Korlym (mifepristone tablets 300 mg) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Korlym?
- Tell all of your health care providers that you take Korlym (mifepristone tablets 300 mg). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Avoid grapefruit and grapefruit juice.
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking Korlym (mifepristone tablets 300 mg) with your other drugs.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also, like a condom, when taking Korlym (mifepristone tablets 300 mg) and for 1 month after care ends.
- If you get pregnant while taking Korlym (mifepristone tablets 300 mg) or within 1 month after your last dose, call your doctor right away.
How is this medicine (Korlym) best taken?
Use Korlym (mifepristone tablets 300 mg) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with food.
- Swallow whole. Do not chew, break, or crush.
- If you have trouble swallowing, talk with your doctor.
- To gain the most benefit, do not miss doses.
- Keep taking Korlym (mifepristone tablets 300 mg) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad dizziness or passing out.
- Very bad headache.
- Shortness of breath.
- Feeling very tired or weak.
- A fast heartbeat.
- Very upset stomach or throwing up.
- Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, change in eyesight.
- Vaginal bleeding that is not normal.
- Chest pain or pressure.
- Swelling in the arms or legs.
- Not able to sleep.
- Low blood sugar can happen. The chance of low blood sugar may be raised when Korlym (mifepristone tablets 300 mg) is used with other drugs for high blood sugar (diabetes). Signs may be dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do if you get low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices.
- A type of abnormal heartbeat (prolonged QT interval) can happen with Korlym (mifepristone tablets 300 mg). Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.
What are some other side effects of Korlym?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Belly pain.
- Loose stools (diarrhea).
- Upset stomach or throwing up.
- Back pain.
- Hard stools (constipation).
- Not hungry.
- Feeling sleepy.
- Dry mouth.
- Joint pain.
- Nose or throat irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Korlym?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Korlym (mifepristone tablets 300 mg) is refilled. If you have any questions about Korlym (mifepristone tablets 300 mg), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Korlym (mifepristone)
- Korlym Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- Drug class: progesterone receptor modulators
Other brands: Mifeprex