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Imipenem, Cilastatin, and Relebactam

Generic Name: Imipenem, Cilastatin, and Relebactam (IM i PEN em, SYE la STAT in, & REL e BAK tam )
Brand Name: Recarbrio

Medically reviewed by Drugs.com. Last updated on Jan 14, 2020.

Uses of Imipenem, Cilastatin, and Relebactam:

  • It is used to treat bacterial infections.

What do I need to tell my doctor BEFORE I take Imipenem, Cilastatin, and Relebactam?

  • If you are allergic to imipenem, cilastatin, and relebactam; any part of imipenem, cilastatin, and relebactam; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have kidney problems.
  • If you are taking any of these drugs: Divalproex, ganciclovir, or valproic acid.

This is not a list of all drugs or health problems that interact with imipenem, cilastatin, and relebactam.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take imipenem, cilastatin, and relebactam with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Imipenem, Cilastatin, and Relebactam?

  • Tell all of your health care providers that you take imipenem, cilastatin, and relebactam. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not use longer than you have been told. A second infection may happen.
  • Severe and sometimes deadly allergic side effects have rarely happened with drugs like this one.
  • This medicine may raise the chance of seizures in some people, including people who have had seizures in the past. Talk to your doctor to see if you have a greater chance of seizures while taking imipenem, cilastatin, and relebactam.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Imipenem, Cilastatin, and Relebactam) best taken?

Use imipenem, cilastatin, and relebactam as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Seizures.
  • Feeling confused.
  • Trouble controlling body movements.
  • Diarrhea is common with antibiotics. Rarely, a severe form called C diff–associated diarrhea (CDAD) may happen. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea.

What are some other side effects of Imipenem, Cilastatin, and Relebactam?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Imipenem, Cilastatin, and Relebactam?

  • If you need to store imipenem, cilastatin, and relebactam at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about imipenem, cilastatin, and relebactam, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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