Wondering if those of you who have started Praluent did so because you experienced muscle pain on statins. If so, have you had any muscle pain that may be associated with Praluent?
I had problems with all of the statins. Pain, weakness and spasms/cramping. I am on a small dose now, no problems. I get my first shipment of praluent tomorrow. Excited to start.
medq; There is not a lot of side effects listed because this one being one of the newer Cholesterol medications but this one is listed.((( muscle spasm with pain))) Which does not surprise me almost all the others due. but it was not that high it says 1 to 10% in the studies had this but not bad enough to have to stop. So you might just give your doctor a call, Maybe like with Ranger an adjustment in dose and diet you may get better results. Hope you get to feeling better.
I have been taking Praluent 75 mg for 8 months. Started August 2015. So far I have not experienced any side effects. I used to have severe back muscle pain when I took statins.
Absolutely none. Been objecting for 3 months. Total cholesterol went from 222 to 87! Had severe muscle pain from statins. This drug is awesome, no side effects at all!
medq; ARE you having problems with cramps pain etc still If they just changed you sometimes it takes a little time to adjust to the new one and so far I have been seeing nothing but good things about this newer statin. Which is very common as they improve them because of problems with some of the older ones AS I said before what it does list is very little when you compare it to the older ones on the market. Hope it is working out for you as well as a lot of the posters here.
yes. I stopped statins because they weren't working to lower my soaring LDLs and caused crippling muscle pain. I started Praluent to control my Familial Hypercholesterolemia with the hope of not having horrible muscle pain. After 9 months of injections, my LDLs are much lower, but I am having significant muscle aches and wonder if this miracle drug is worth the PAIN. I only agreed to take it because it wasn't supposed to cause muscle pain like the (useless) statins. SO, NOW WHAT? Discontinue Praluent & wait for a heart attack or stroke or continue to suffer horrific muscle pain? I joined a gym to get healthy, but am unbelievably sore after the lightest workout. HELP!!!
It's been about 6 months since I started Praluent and I haven't noticed any extra pain. I already have Fibromyalgia and arthritis in my back and was afraid of statins causing even more pain than I currently have. My LDL has gone down over 50 points and my triglycerides are almost normal. Hopefully it keeps working its magic and I don't have any problems.
Yes I have pain all the time, beside that I have memory loss and I lost too much weight as I was too thin to begin with.. Not my favorite drug but statins dont work with me
Just wanted to follow up on my question in February regarding Praluent and muscle pain. Most of us, I believe, are eager to hear what others with Familial Hypercholesterolemia have experienced after discontinuing statins owing to muscle pain and other side effects. I completed a trial of Praulent for about three months, but my doctor decided the small change in my cholesterol didn't warrant continuing. While there seems to be some question that Repatha will be anymore effective, I agreed to give Repatha a try and will share any useful results in a few months.
In regard to muscle pain with Praulent and Repatha, I think these two drugs are just too new to give anyone a clear picture of the scope of possible side effects.
I also want to respond to Celeste regarding her experience with exercise and suggest that she may want to search online for medical studies focusing on exercise and statins.
Thanks to everyone who has responded thus far.
Your last post thank you very much it is nice to know, And like you said these new ones are very hard to answer until they have been out for awhile. And also since you had written you last post on the Praluent the doctors are using much more caution on the statins that cause severe leg and other cramps. Some people have stopped many statins and the cramps continue for who knows how long. thank you so much for adding this.
Yes, I had pain radiating from shoulder with all statins. It wasn’t worth the pain given my levels were not too bad in the first place but cardiologist wanted lower due to aortic aneurysm. The Praluent works great but after several months I am developing uncomfortable levels of pain in my legs especially the leg where I inject most frequently. If this continues and I can pinpoint my problem to the drug. I’m discontinuing.
I'm a 72 year old man taking 75mg Praluent 75mg injections every other week for the last 6 months along with Lipitor statin 40mg daily. I get no side effects from the Praluent. I do get muscle pain from the 40 mg. Lipitor statin. Both of these meds have lowered my LDL (Bad Cholesterol) from 300 when I had my heart attack 1 year ago all the way down to 40mg/dl. Yes 40 ! Amazing stuff. Only complaint is the price of Praluent which the manufacturer has just announced a price reduction of over 60% beginning March 2019. I also take a pain pill every morning to make the slight muscle pain go away. I'm very happy with these results and plan on taking these meds forever even though there are side effects that I can tolerate.
I am in my 3rd year of Praluent. It's nothing less than a miracle drug for me. It dropped my cholesterol from a start of around 250 to 107 on last test. I only inject once every three weeks instead of two. I'm going to a once a month injection starting with my next injection. 75mg.
I took it after trying about 4 different statins with horrible muscle cramping. Mainly in the legs and calf's. Absolutely no side effects with Praluent. I hope it works as well for you.
I started the Praluent 75mg injections in my legs on Sept. 7, 2018. I'm on my 13th injection. So far I don't notice any side effects. I do get muscle pain from statins. I take an over the counter pain pill to make the pain go away. Statins reduced my LDL from 200 to 80mg. Adding the Praluent lowered my LDL down from 80mg to 40 LDL very quickly. I'am very happy with the results and also the 60% price drop announced by the manufacturer coming in March 2019.
Hi, I originally was on repatha. I had MI and multiple white matter scars of my brain. I'm just 64 and was selected as a candidate for this particular group of drugs.
To be honest just after the first injection, I felt strangely full up and had difficulty swallowing, now, not critical but uncomfortable . I had tightness in my chest very similar to my MI. Anyway this drug had very serious side effects.
My Dr then decided to try Praluent 75mg. I was hoping this would be more tolerable, well it was exactly the same. Don't know why, but both these inhibitors, caused multiple issues, as a matter if fact, I can't think of somewhere that didn't hurt. I have had several MRI over the last 20 years, strangely I had a CMRI when I was really sick with Praluent and for the first time there was gadolinium enhancement in the left ventricle suggesting inflammation. This had never been there before.
I am not saying the Praluent caused this, but I had a very bad inflammatory responce to both of these similar drugs. Absolutely horrific.
I am still having abdominal discomfort, with slight difficulty swallowing, chest discomfort and joint pain.
Multiple other side effects, point being that in my case had very very serious effects.
As with repatha, I will now have to wait for weeks for all this to settle down.
- Praluent Information for Consumers
- Praluent Information for Healthcare Professionals (includes dosage details)
- Side Effects of Praluent (detailed)
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