Wellbutrin - Bupropion XL 150 make anyone else tired?

I have been on Wellbutrin for 4 days now (XL 150 take one in morning) and I, not unlike the others here, am very tired around 3:00 or 4:00 pm. I am very aware of symptoms in my body and this is clearly new for me. I am guessing it will subside over time. Not foggy just tired.

I started taking this for mild depression and ADHD. I too experienced tiredness, especially the first week. I was dehydrated! The tiredness went away after I started drinking A LOT more water. If you experience this, try drinking a lot more water than you normally do. It should help. If not, see stop taking it and talk to your doctor.

Wow me too!
I have been taking it in the morning 8am and I've been napping all~day. I've been on it for about a week & 4 the last few days I've been exhausted. I'm just now realizing that it's the Wellbutrin. I wonder if I take it at night will it help me sleep! I was on Zoloft but I gained 20 pounds in less than 2 months..

I am on day 13 of taking Wellbutrin XL 150 mg per day; I take it at 6 am every day. So far, I have not experienced any side effects other than severe hot flashes once or twice a day - the sweat pours off of me and it lasts for several minutes. This medication has definitely improved my ability to sleep at night! I become really tired by 9 pm, asleep by 10 pm and sleep through the night until 5 am. I haven't been blessed with the gift of sleep for many years - was averaging 2 to 3 hours a night with multiple wake-ups in-between. I feel mellow but focused on this medication. No tears the past three days. Not sure if the medication is helping with the tears, or if getting restful sleep is helping with the tears. Either way - it feels good to be rested.

I started Bupropion 14 days ago and wasn't having any side effects except for an almost non-existent appetite up until two days ago when I started to feel very tired. I laid in bed for about two hours after waking and that is something I NEVER do because I can never just lay in bed not doing anything. Same thing this morning. I decided to take my daily dose in the p.m. to see if that will help. I really hope this drug works for me. I do know one thing; my libido is back with a vengeance so I'm thinking that's a good sign.

Yes. I get extremely sleepy. My Dr told me that I could take it in the evening or w/my seroquel @ bedtime. I normally take it around 6pm, however when I forget, I take @ bedtime. Taking it in the evening gets me in the slow down mode, so when I take my nightly meds, I've got a headstart to b able to sleep. The Dr told me that it's unusual that it makes people get sleepy, tho others do experience it. I still have that side effect & I've been taking it since Mar 1, 2017. Hope that helps others to know, they're not the only one's that has that side effect.

Same here. I was on Vyvanse 30mg which helped with concentration but I still didn't have enough energy, so 2 weeks ago, we added Wellbutrin XL 150mg. Its had the opposite of the intended effect, seems to have diminished the effect of vyvanse and by 4 or 5, I feel totally wiped out and just want to go home and get into bed (which I can't do with 2 young kids). I've tried playing around with the times of administration for both meds, but nothing has helped.

I began 150mg Wellbutrin a week ago, added to 100mg Zoloft that I've been taking for two years. The first day I had shakes that led to serious fatigue. No more shakes after that but have been completely exhausted by 2pm and have no difficulty laying in bed for hours, I have no energy. It's only been a week so I'll give it more time but it feels horrible.

Yes I am having the exact same experience! Wellbutrin im on my second day and im completely wiped it is 1:30 pm and i just realized this happened yesterday too. I may try a stimulant around this time of day to combat this, like green tea or something. But I was encouraged to give it time while system adjusts.

If it makes you so tired, why don't you try taking it at bedtime? You would probably get a good night's sleep and be alert the following day. And your doctor might discuss this with you, and he might suggest upping your dose to 300mg.
Wellbutrin is usually known to be a stimulating medication. Maybe a different dose and different time to take it will help?

I started taking 150 xl about 5 days ago and I am wiped out by 2 to 3 in the afternoon to the point in which I can't function. I take it in the am with adderall and it still drains me. It's like living in a state of pure exhaustion so I'm extremely calm because i just want to sleep. Trying to determine whether or not to stop it.

Glad I found this particular thread, even though it's a bit old. I've been on Wellbutrin for quite some time, and had been very happy with it. More recently, I noticed days where I felt like I was in a fog, and I was constantly exhausted by the afternoon. I had chalked the exhaustion up to something else. That something else may be a factor, but maybe not the main culprit.

I've taken myself off for a few days. So far my energy seems to be better and I think I'm seeing things a bit more clearly. I seem to be very sensitive to a number of drugs, so I wouldn't be surprised if I happened to encounter a lesser known side effect.