Wellbutrin - Bupropion XL 150 make anyone else tired?

I've been on 150mg generic Wellbutrin for almost 6 weeks. I was weaning off of pristiq until the 4th week... then they bumped me up to 300mg when the pristiq stopped. I have been exhausted. Had to take this week off work. Take the meds in the morning and end up going back to bed for the whole morning as I would usually end up with a crying fit and anxiety after I took it. Today I'm trying to cut it down back to 150mg and see if it helps. You think after 6 weeks things would level out. I have to go back to work tomorrow and I'm terrified. I can't sleep all morning forever. Today I woke up early due to kids and cat and took one pill and went back to bed til 8:30am... I seem ok now. Not too tired. I don't like this drug except finally after so many years my libido is back. Well I don't actively want sec but when I do it's a whole new ball game having all that sensation back. It's insane.

I have taken it for almost a week, and I feel very tired in the afternoon. I was hyped up the first two days, now I am sleepy. Also, I am gradually coming off Zoloft at the same time, maybe that is the problem.

I have been taking Bupropion SR 150 mg. this is day three and I am so damn tired too. I am giving it a chance though. I'm off from work for a few weeks so I'm dealing with it. At first I wasn't sure if it was the Xanax I have been taking to sleep. I think I'm going to cut back on the Xanax to see. I took led apron for about 8 years. Worked great but realized how I ballooned on it. I've worked hard to get " my body back" and wanted to try something different. I was medication free for about a year and a half but a recent relationship issue has set me back. Exercise and natural serotonin is really really helpful. That and being single seems to be when I'm at my best. Lol. Anyway, give the Wellbutrin a chance to settle in.

I just was prescribed Wellbutrin XL 150mg for depression and anxiety, and for help with fatigue/lack of motivation and focus. I switched from cymbalta which left me very tired with sexual dysfunction. So far, after a few days on Wellbutrin I have not had any positive effects. I'm exhausted, no change in mood. Is this nornal? I thought this would give me a complete opposite effect from cymbalta.

I feel the same way i have been on wellbutrin xl 150 mg for a few day's, I am really mellow and tired that's about it , no anxiety just really drained no energy little appetite just want to sleep.

Ditto over here. I've been taking it for going on 2 weeks now and I am sure it is this that's making me so tired. Can't wait to get this smoking issue out of my life so i can stop this medicine, but it is working wonders for me in my quest to give up cigarettes so I'm living with the tiredness for now

Hi A2 It just might be because its new but this side effect is almost always the other way around you take it in the am because it stimulates most people where they can't sleep,if it continues call the doctor.But like i said we are all different and that is why drugs can work diffetent on some people this should really go away soon if not call your doctor... Chuck1957 medically Retired Pharmacy Technician Cpht I hope this well help you. cw