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Vraylar - What are some of the important warnings?

Answers (1)

Official Answer by Drugs.com 9 Mar 2016

Vraylar (generic name: cariprazine) is an antipsychotic medication that is used to treat schizophrenia and bipolar disorder.

Vraylar, like other antipsychotic drugs, is not approved for use in psychotic conditions related to dementia such as Alzheimer's disease. Vraylar may increase the risk of death in older adults with dementia-related conditions.

Other warnings include:

  • increased risk of cerebrovascular disease, such as a stroke or transient ischemic disease (TIA), in elderly patients with dementia-related psychosis;
  • elevated risk of neuroleptic malignant syndrome;
  • possible risk of tardive dyskinesia;
  • long-half life of drug requires side effect monitoring for several weeks at onset of therapy or after dose change;
  • monitor for metabolic changes like high blood sugar, diabetes, weight gain and elevated lipids like cholesterol, LDL, and HDL;
  • possible increased risk of orthostatic hypotension which may lead to fainting and falls.
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