Has anyone experienced rapid weight gain on Linzess?

I started Linzess in June and I have gained 17 lbs! Haven't gained that much since I graduated in 1984. Checked my thyroid, hormones and ruled out other conditions, so it has to be this medication. I now look like a python that ate a cow. As of reading this feedback from others in the same boat, I'll no longer take Linzess. The results I received are not good enough to outweigh the weight gain. Thanks to everyone for your input. My Pharmacist recommends that anyone having these issues contact the FDA and share with them.

Anyone doubled up on linzess? If so what was results.

This has all been helpful. My doc gave me some samples and I wanted to read reviews before taking them. I already suffer from weight gain due to thyroid and don't need any more help with that. I'll try to stay on the dieters tea and prune juice but the cramping is horrible... wish me luck in finding the right regimen of the 2 to live without cramps and without constipation. Any other ideas???

Been on this med for almost a month. No weight gain or loss. However, I work out and maintain a mostly healthy diet not sure if I decreased my work outs if I would gain. I'm on the low dose and I still only go every 4-5 days. Better than I was but not great. If I miss a dose I hurt badly and my stomach cramps. I'm thinking of asking my Dr to up the dose. At this stage a little loose stool sounds welcoming! I tried Amitza about 5 years ago and it caused lots of problems.

I started to take linzess 4 months ago. I was diagnosed with ibs-c. My doctor had me trial the 290 mg and then the 145 mg. I am 5'2 and was 128 lbs. I take the 145 every other day and now weigh in at 133. I have stayed at that weight since only taking the pill every other day. If I tAke the pill everyday I look prego for sure. Now I look normal again!

I was diagnosed with IBS-C almost a year ago. My symptoms came on over night. One day I was fine the next I was so sick I could barely sit up straight. After going to the dr for weeks they sent me to a gastrointerologist. He deduced, after a colonoscopy, and lots of blood, work what I had. My dr also prescribed me linzess. At first it too worked great, then over time less effectively. I've tried amitiza and every over the counter laxative I could find. But over all linzess works the best. The side effects are annoying most of the time, and I do sometimes have trouble going even after taking the med but over all im better with it. Weight gain is something ive noticed is a side effect. I thought it was just me even though im on a high fiber diet and eat less than I probably should. I've tried to different diets, and pills but I'm stuck with the extra 10 pounds. My stomach is so bloated all the time, I don't just bloat in my stomach, I bloat every where.

I have been on this medication for one month and I have gained five pounds. At first I couldn't figure it out, because weight gain wasn't a side effect. I work out and eat sensibly, so I was already losing weight, now I'm gaining.. The only thing that I was doing differently was taking this medication. So when I googled "does Linzess cause weight gain", it's nice to know this isn't just in my mind.

I was first given samples of this medication for chronic constipation due to IBS and medication (Cymbalta) side effects. I was given the impression then to take Linzess when I needed it (every other day or two - taking something is the only way I can go)so I did and it worked within 2-4 hours of taking it. Perfect, I thought. I could plan around work and other obligations to be near a bathroom. Since it worked well, the doctor have me a prescription and I began taking it according to the official directions of taking it in the morning on an empty stomach. Now I am on day four without a bowel movement. Has anyone else experienced this? Is there anything wrong with taking it later on the day and after I have eaten? I didn't have weight gain using it the way I had been using it and it was effective in getting me to go.

I have been on it for a little over 2 weeks now, the higher dose, and I have actually lost almost 10 lbs. I was suffering from horrible issues for over 6 years old, so since i was 19, and within a couple days of starting the meds my digestive track has never felt better. The constipation was causing my weight gain so this medication has helped. But like any other drug it does not work the same for everyone.

I have been on this medication now for about 5 - 6 weeks and I have also gained weight. I also would like to know if this is normal?

I have gained 8 pounds

I've been taking Linzess for about 5 months, and have actually lost about 5 pounds. I don't attribute the weight loss to the medication because I had been working on losing a few pounds.

However, I have experienced nearly constant diarrhea since taking Linzess. My Gastroenterologist suggested cutting the Miralax back to once or twice a week, which I have. I had my gall bladder removed on December 17th with no issues, but went back to the surgeon last week with pain in the mid to lower right side. He ordered another CT Scan with contrast and when I saw him on Thursday he said the doctor reading the scan suspected my appendix of causing the problem, so I'm on 10 days of Augmentin and go back to the surgeon next Monday for another CT Scan if necessary. Good Grief!

I have been on it for several months & have gained 7lbs and counting. I'm often ill with GI issues nausea, bloating ect
My stomach is enlarged & I can't lose weight. Without it I have really bad IBSC & pain. Thinking about going off med. not sure what to do.