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What is the difference between Apadaz and Vicodin?

Answers (1)

Official Answer by Drugs.com 18 Jun 2018

Vicodin is an immediate-release pain reliever medication that contains a combination of acetaminophen and the opioid hydrocodone. Vicodin tablets are used for the relief of moderate to moderately severe pain. Acetaminophen is a less potent pain reliever that can add to the pain-relieving effects of opioids (sometimes called narcotics, or narcotic analgesics).

Apadaz is an immediate-release combination of the prodrug, benzhydrocodone, and acetaminophen. When ingested, stomach enzymes cleave the benzhydrocodone prodrug and release the active parent drug hydrocodone. Apadaz is also used for the short-term (no more than 14 days) management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Apadaz, from KemPharm Inc., was approved by the FDA on February 23rd, 2018.

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