Gabitril Side Effects

Generic name: tiagabine

Medically reviewed by Drugs.com. Last updated on Oct 2, 2023.

Note: This document provides detailed information about Gabitril Side Effects associated with tiagabine. Some dosage forms listed on this page may not apply specifically to the brand name Gabitril.

Applies to tiagabine: oral tablet.

Serious side effects of Gabitril

Along with its needed effects, tiagabine (the active ingredient contained in Gabitril) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking tiagabine:

More common

• blue or purple spots on skin
• difficulty in concentrating or paying attention

Less common

• burning, numbness, or tingling sensations
• clumsiness or unsteadiness
• confusion
• itching
• mental depression
• speech or language problems

Rare

• agitation
• bloody or cloudy urine
• burning, pain, or difficulty in urinating
• frequent urge to urinate
• generalized weakness
• hostility
• memory problems
• quick to react or overreact emotionally
• rash
• uncontrolled back-and-forth and/or rolling eye movements
• walking in unusual manner

Symptoms of overdose

• agitation (severe)
• clumsiness or unsteadiness (severe)
• coma
• confusion (severe)
• drowsiness (severe)
• increase in seizures
• mental depression
• severe muscle twitching or jerking
• sluggishness
• speech problems (severe)
• weakness

Other side effects of Gabitril

Some side effects of tiagabine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• chills
• diarrhea
• dizziness
• drowsiness
• fever
• headache
• muscle aches or pain
• nervousness
• sore throat
• tremor
• unusual tiredness or weakness
• vomiting

Less common

• abdominal pain
• flushing
• impaired vision
• increased appetite
• increased cough
• mouth ulcers
• muscle weakness
• nausea
• pain
• trouble in sleeping

For healthcare professionals

Applies to tiagabine: oral tablet.

Dermatologic

• Very common (10% or more): Common (1% to 10%): Rash, pruritus
• Uncommon (0.1% to 1%): Dermatitis bullous dermatitis, bruising
• Frequency not reported: Vesiculobullous rash, exfoliative dermatitis^[Ref]

Cardiovascular

• Common (1% to 10%): Vasodilation^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea (11%)
• Common (1% to 10%): Abdominal pain, diarrhea, vomiting, increased appetite, mouth ulceration^[Ref]

Hepatic

• Very rare (less than 0.01%): Abnormal hepatic function (elevated SGPT, GGT)^[Ref]

Musculoskeletal

• Common (1% to 10%): Myasthenia, muscle twitching^[Ref]

Immunologic

• Very common (10% or more): Infection (15%)
• Common (1% to 10%): Influenza syndrome^[Ref]

Nervous system

• Very common (10% or more): Dizziness (27%), asthenia (20%), somnolence (18%), nervousness (10%), tremor
• Common (1% to 10%): Ataxia, paresthesia, abnormal gait, nystagmus, speech disorder
• Uncommon (0.1% to 1%): Nonconvulsive status epilepticus
• Frequency not reported: Encephalopathy^[Ref]

Ocular

• Very common (10% or more): Blurred vision, visual field defects
• Common (1% to 10%): Amblyopia, diplopia^[Ref]

Respiratory

• Common (1% to 10%): Pharyngitis, cough, rhinitis^[Ref]

Psychiatric

• Common (1% to 10%): Difficulty with concentration/attention, insomnia, confusion, memory loss, depressed mood, emotional lability, hostility/aggression, agitation
• Uncommon (0.1% to 1%): Depression, psychosis
• Rare (0.01% to 0.1%): Hallucinations, delusion^[Ref]

Other

• Very common (10% or more): Accidental injury (17%)
• Common (1% to 10%): Pain (unspecified), fatigue^[Ref]

Further information

Gabitril side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer