Estazolam Side Effects
Some side effects of estazolam may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to estazolam: oral tablet
Estazolam may cause a severe allergic reaction. Stop taking estazolam and Get emergency medical help if you have any of these signs of an allergic reaction while taking estazolam: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using estazolam and call your doctor at once if you have any of these serious side effects:
weak or shallow breathing;
fast or pounding heartbeats;
confusion, slurred speech, unusual thoughts or behavior;
hallucinations, agitation, aggression;
thoughts of suicide or hurting yourself;
restless muscle movements in your eyes, tongue, jaw, or neck;
pale skin, easy bruising or bleeding, unusual weakness;
fever, chills, body aches, flu symptoms;
problems with urination; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects of estazolam may include:
daytime drowsiness (or during hours when you are not normally sleeping);
amnesia or forgetfulness;
muscle weakness, lack of balance or coordination;
numbness, burning, pain, or tingly feeling;
headache, blurred vision, depressed mood;
feeling nervous, excited, or irritable;
nausea, vomiting, stomach discomfort; or
dry mouth, increased thirst.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to estazolam: oral tablet
Two cases of seizures following discontinuation of estazolam have been reported.
Nervous system side effects have been common and included drowsiness, sedation, headache, dizziness, hypokinesia, and ataxia most frequently. Anxiety has also been reported.
Other side effects have included tolerance to the pharmacologic effects of benzodiazepines and withdrawal symptoms after either abrupt cessation or fast tapering of estazolam. Withdrawal symptoms have included agitation, restlessness, anxiety, depression, insomnia, tremor, abdominal discomfort, blurred vision, vomiting, sweating, and seizures.
However, one study of single high doses of estazolam given to healthy volunteers revealed no evidence of respiratory depression during wakefulness.
Respiratory side effects have included dose-dependent respiratory depression. Estazolam-induced respiratory depression is generally not clinically significant at the usual hypnotic doses. However, patients with impaired respiratory function may be at greater risk of estazolam-induced respiratory depression.
Gastrointestinal symptoms including nausea, constipation, bad taste in mouth, and dry mouth have been reported.
More estazolam resources
- estazolam MedFacts Consumer Leaflet (Wolters Kluwer)
- estazolam Concise Consumer Information (Cerner Multum)
- estazolam Advanced Consumer (Micromedex) - Includes Dosage Information
- Estazolam Prescribing Information (FDA)
- Estazolam Professional Patient Advice (Wolters Kluwer)
- Estazolam Monograph (AHFS DI)
- Prosom Prescribing Information (FDA)
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.