User Reviews for Doxepin

Also known as: Adapin, Silenor, Sinequan

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Doxepin.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Irritable Bowel Syndrome 1 reviews 129 medications
   
10
Major Depressive Disorder 1 reviews 44 medications
   
10
Depression 5 reviews 75 medications
   
8.3
Insomnia 103 reviews 102 medications
   
7.4
Urticaria 6 reviews 192 medications
   
6.8
Anxiety 8 reviews 61 medications
   
6.6
Reflex Sympathetic Dystrophy Syndrome 1 reviews 2 medications
   
3.0
Summary of Doxepin reviews 125 reviews 7.3

Reviews for Doxepin

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For Insomnia: "This made me sooooooo tired and drugged feeling I could barely wake up! It was terrible! I hate insomnia but this was ridiculous! This stuff is not a solution! Unless all you do is sleep. So frustrated! Thought this was the one!"

   
2.0

Benzo addict May 18, 2015

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For Anxiety: "Been on many SSRIs, a few SNRIs, and some of the TCAs. I took Tofranil (imipramine) for about 6 months on a starting dose of 25 mg and eventually increased slowly to 125mg. Over the course of those 6 months, my anxiety was under control for the most part, but I developed myoclonus and had to stop taking the drug. I switched to Sinequan (doxepin) 25 mg, increased to 75 mg, divided into 25mg three times a day and have done well, without any side effects besides mild fatigue. No bad thoughts, lingering anxiety or panic attacks. Very successful drug (doxepin) for me so far. Been about 3 months now."

   
9.0

DKT26 May 17, 2015

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Silenor (doxepin) for Insomnia: "This stuff really did the job. It knocked me on my booty and I am used to taking medications that make you sleepy. This kept me sleeping all night long after about 3 weeks of falling asleep and not being able to stay asleep for more than an hour or two. My prescription is for 25 mg and I only took a half. Just to let you know, You may want to try it when you do not have to work the next day. I am not sure if I could have gotten up in time for work this morning if I had to. I do all medications like this slowly and I never start out at my prescribed dosage. I always start out a lot lower dosage and go up from there if I need to. I do feel a bit of anxiety today. Not sure if it's the medication, or? I am wide AWAKE now. A bit strange."

   
8.0

Urbangirl (taken for less than 1 month) March 29, 2015

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For Urticaria: "Amazing! I was put on Doxepin a few months ago and it has done wonders. I used to break out in hives 4-5 times a day. Now I only break out 1-2 times a month. Very serious progress!"

   
8.0

Paisley12345 (taken for 1 to 6 months) March 22, 2015

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For Urticaria: "Very effective for treating Urticaria, almost completely eliminated my hives. Had to come off because doxepin caused major depression. Within three days of stopping Doxepin, my depression subsided."

   
2.0

Anonymous March 17, 2015

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For Anxiety: "Especially good for helping you stay asleep! The problem is that I slept 12 hours straight and most of the next day. I didn't really have an issue staying asleep before- my issue is more with relaxing/ going to sleep at appropriate times. So, if you have a lot of trouble staying asleep, this definitely works. No terrible side effects, was just very sleepy. If you really need the sleep, go for it!"

   
5.0

KellyBird57 (taken for less than 1 month) February 24, 2015

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For Insomnia: "Prescribed doxepin in detox/rehab after traxadone did not work well. 25mg of doxepin works really well for me. 120 lb female age 26. Helps with anxiety and keeps me asleep even if I wake up to pee or something. I have gained some weight but I can't attribute it to the doxepin since I am only two months clean off opiates. But for addicts, definitely give it a try cause it worked wonders for me. Non habit forming too."

   
10

Olsensan February 9, 2015

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For Insomnia: "Helped me a lot with my insomnia. But gained over 50 pounds in the last 4 months. I have also noticed my hair getting thinner. I will not take this anymore. Going back to the dr."

   
3.0

Anonymous (taken for 1 to 6 months) February 2, 2015

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For Urticaria: "I am 34 year old female.. I am on Doxepin to help me sleep.. I have had SEVERE eczema for years- NOTHING helps except prednisone ( on that now all the time too) but I couldn't sleep due to constant scratching.. Slowly increased Doxepin until Im now at 100mg taken at night ( sometimes depending how tired I am I only take 50-75mg) but Its my miracle pill.. Puts me to sleep ( almost instantly) and 99% of the time im not tired or groggy in the morning... I have heard however-there is possibility of weight gain and thinning hair at which both possibilities would cause me to look for a different medication.."

   
9.0

Sarah 1980 November 19, 2014

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Silenor (doxepin) for Insomnia: "I've been on Ambien and it was too strong. It gave me brain fog the next day. Taking half a pill helped but I did not like that it was habit forming. Got some samples of Silenor 3mg and it helped keep me sleeping or if I woke up I would go back to sleep. I only take half a pill with an 8 oz glass of water and that does the trick. It also helps to use earplugs to keep out noise. Ive noticed that some people complain of weight gain. I cant imagine how that could happen if you are sleeping. But if Im awake and nibbling in the middle of the night, unless I up my exercise it's to be expected."

   
9.0

Cant find a nickname November 14, 2014

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For Insomnia: "I am an addict and have had chronic insomnia for 20 years, so as you would imagine I've tried everything and abused everything. Doxepin is a miracle med for me. I take 10 to 30mg depending on how sleepy I am. I have no side effects, no weight gain, no sleepiness the next day. Want extra help? Read up on Magnesium. Just added that with amazing results. Depression and anxiety...well haven't found the miracle for those yet."

   
10

EverydayAddict (taken for 6 months to 1 year) November 1, 2014

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Silenor (doxepin) for Insomnia: "Was too sedative and I always woke up tired the next day and it made my heart feel heavy and it felt like it was beating slow."

   
2.0

ann702 (taken for less than 1 month) October 8, 2014

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Silenor (doxepin) for Insomnia: "For as long as I can remember, I have had issues with falling asleep and remaining asleep. This occurred in childhood also. It seems to be a family trait. However, my doctor prescribed Silenor and what a difference this pill makes! To have always had problems sleeping and then suddenly, a pill changes the problem. Over the years I have taken, Lunesta, Ambien, Tylenol PM, Melatonin, Benadryl...all stopped working within a period of 3-5 months. Not so with Silenor. I read some posts stating that Silenor has caused weight gain. I have not noticed such, but I do not keep a weight scale in my house. For the present, I will only say that for a chronic lifetime insomniac, I wish that I had this pill 44 years ago. Age now 49."

   
8.0

zanylisa (taken for 1 to 2 years) September 8, 2014

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Silenor (doxepin) for Insomnia: "I was on zopiclone for about 14 years and was successful in weening myself off but having difficulty sleeping again. Doctor prescribed Silenor 3mg and with directions "take 1 or 2 tablets as needed". I've opted to take 1/2 tablet (1.5 mg) to start. I've been sleeping and feeling rested on awakening. Not sure if it's psychological or not."

   
8.0

Bccmor September 8, 2014

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For Insomnia: "This medication is the first I've tried for insomnia and it's better than nothing, but there has to be something better. I have problems staying asleep and 80% of the time it helps that, and if I wake up for the bathroom or a snack (okay two snacks), I can fall back asleep quickly. But the weight gain! I had no idea it would cause me to gain so much in a short period. 25 or so pounds in 3 months. I will be looking into Prosom instead and hopefully be able to drop this weight."

   
6.0

Veronica M August 22, 2014

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Sinequan (doxepin) for Major Depressive Disorder: "It has greatly improved my mood and I have been sleeping wonderfully too."

   
10

Tiptoptf (taken for 6 months to 1 year) August 16, 2014

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For Insomnia: "I started this medication about 10 days ago. Doxepin, 10mg, has been working more days than not. Like most medicines, the first few days it worked like a charm. I took it and I slept about 5.5 hours straight. Sometimes can go back to sleep for another 1/2 an hour. I do feel a little help in the anxiety category. Not a lot but it does help a bit. The bad thing about this medicine is that you feel very sedated throughout the day. You know you slept because of the vivid dreams and you don't wake up the whole night. Nevertheless, you feel extremely tired the whole day. I wish I didn't have to take medicines. But I rather be feeling sleepy and knowing that I slept as opposed to feeling sleepy due to no sleep."

   
7.0

aquabohdi August 10, 2014

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For Anxiety: "My Dr. Prescribed me Doxepin 10mg. For depression, anxiety, and insomnia. So far so good, calms me down wonderfully when my three kids or my husband cause me to have an anxiety attack, and is working well with my depression. Only things it isn't doing to much for my insomnia I still go to bed at about 9pm and fall asleep around 2:30-3:00am. I have also taken Lexapro which worsened my depression, Zoloft just made me feel like a zombie or like I was wired out of my mind, and Prozac which worked great on me but since I have insomnia my Dr. gave me Doxepin."

   
6.0

Buffs June 23, 2014

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For Insomnia: "I've suffered with insomnia fire several years now. At times sleeping only 1 hour before having to get up to go to work. My Dr. prescribed Silenor but my insurance gave me Doxepin (25mg). Biggest mistake I made was taking right before bed because it doesn't help you fall asleep, only helps you stay asleep. Once I fell asleep, I didn't wake up at all until the following morning. If you have children or anyone else to depend on you for care, I wouldn't recommend it. I was actually awakened by my boys and I felt very drowsy, groggy, and irritable. So much so that I caught myself yelling at my kids. I wasn't able to function 100%. This would ONLY be good if you have nothing to do or no-one to care for the next day. "

   
5.0

Anonymous221098 June 14, 2014

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For Insomnia: "I love it."

   
9.0

Anonymous June 12, 2014

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Silenor (doxepin) for Insomnia: "I find it works really well keeping me asleep all night, I do have some wild vivid dreams but not that often, only down side for me is I am gaining weight"

   
10

Hot mom (taken for 1 to 6 months) June 7, 2014

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Silenor (doxepin) for Insomnia: "I couldn't stay asleep, tried Lunesta and Ambien, they had side effects I couldn't tolerate. Sleep center said I had mild apnea and said their monitors showed me sleeping but I felt like I was awake more than they said I was and was literally exhausted every day, felt like I was on the verge of "losing it," crying a lot. Was not sad/depressed--was sleep deprived. Have been taking 2 Silenor a night for 2 years: sleep like a baby, 8 hours required, wake up rested, functioning beautifully--I have my life back."

   
10

AnnieSmith11 May 13, 2014

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For Insomnia: "Doxepin is great at keeping me asleep. The only major problem is the rapid weight gain. I went from 155lbs to 185lbs in only 2 weeks. "

   
10

No Doze (taken for 1 to 6 months) May 7, 2014

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For Depression: "I have been taking doxepin at 25mg for about a month for depression, chronic pain and anxiety. All was somewhat fine, no side effects. To get the medicine working better, my doctor raised my dose to 50mg about 2wks ago. I am very happy so far."

   
9.0

Anonymous April 28, 2014

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For Insomnia: "Developed acute insomnia immediately following a bad concussion. I would doze off but would wake up within 30 minutes, unable to fall back asleep for hours at a stretch. Tried several sleeping medications (off-label use trazodone, Ambien, melatonin, OTC sleep aids. with no success for several weeks and was getting desperate. A mere 3mg of Doxepin saved my life. I slept for six straight hours the first night and it only got better and better. I take 3mg around 9pm, sleep from 11pm to 6am very reliably and have few side effects besides a small amount of weight gain (about five pounds in my first two weeks) and slight drowsiness in the mornings and mid-afternoons. I'm so grateful to have my sleep back."

   
10

Post concussion April 24, 2014

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