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User Reviews for Doxepin

Also known as: Adapin, Silenor, Sinequan

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Doxepin.

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Irritable Bowel Syndrome 1 reviews 125 medications
   
10
Depression 3 reviews 81 medications
   
7.8
Insomnia 73 reviews 98 medications
   
7.5
Urticaria 3 reviews 184 medications
   
7.3
Anxiety 2 reviews 63 medications
   
7.0
Reflex Sympathetic Dystrophy Syndrome 1 reviews 7 medications
   
3.0
Summary of Doxepin reviews 83 reviews 7.4

Reviews for Doxepin

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Review by Good to know (taken for 1 to 2 years):

Silenor (doxepin) for Insomnia: This medicine worked beautifully for me; I have no complaints. But when my insurance changed and I couldn't take it any longer, I had to try and go without it. I didn't realize that it had been the source of my weight gain and why I couldn't lose the weight no matter what I tried. After stopping taking it I dropped 10 lbs almost immediately WHILE I WAS ON SPRING BREAK and eating way more than usual and not working out 4 times a week as usual. I'm glad I took it and that it helped me, but I just wanted to share this experience so that others won't mistakenly think that age was causing them to gain weight and not lose it no matter what they tried.

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April 19, 2013 5:12 PM
Review by Ktired: User Rating:  
   
1.0

Silenor (doxepin) for Insomnia: I had horrible nightmares and intermittent sleep. Very frustrated. Woke up tired.

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April 15, 2013 12:00 PM
Review by johns285 (taken for 1 to 6 months): User Rating:  
   
2.0

Silenor (doxepin) for Insomnia: This medicine was just like taking Benadryl, only more expensive. An hour to two hours after taking Silenor, I still couldn't fall asleep...not even the slightest bit tired. Once I had fallen asleep, I would wake up 2-4 hours later and be wide awake for the rest of the night.

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March 24, 2013 6:33 AM
Review by SleepyNess: User Rating:  
   
10

Silenor (doxepin) for Insomnia: I too have tried Ambien and since I heard many of my friends become slightly addicted to it, my doctor switched me to Silenor. It definitely works! And it doesn't give me that weird feeling like Ambien did at times. Couple of my other friends also say it worked for them. Copay was just as much as Ambien on my insurance.

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March 2, 2013 8:46 AM
Review by Insomniac1985 (taken for 1 to 6 months): User Rating:  
   
9.0

doxepin for Depression: I've been diagnosed with chronic insomnia and general anxiety for 9 years. I also suffer from depression, but refuse to be medicated directly for it (specifically SSRI's) after dealing with Paxil and the horrible withdrawal I experienced 8 years ago. So recently I was prescribed 30mg Doxepin in addition to my Zolpidem (Ambien) for my insomnia. My insomnia has slightly improved, but more pronounced has been the reduction in both occurrence and severity of my anxiety (within the first week) and depression (after about 3-4 weeks). It's been about 6 weeks since I started the doxepin and haven't noticed any negative side effects besides some dry mouth/eyes, which is far outweighed by the benefits I've received.

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February 27, 2013 2:09 AM
Review by Mikeodean (taken for less than 1 month): User Rating:  
   
3.0

Silenor (doxepin) for Insomnia: Medicine kept me from sleep. It had the opposite effect.

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February 17, 2013 11:02 PM
Review by MDKPS: User Rating:  
   
10

doxepin for Irritable Bowel Syndrome: I have battled stomach pains so bad it sent me to the ER. tests were run and always the same thing, liver enzymes up off the chart or sugar levels not right, white blood cell extremely high, but by the next morning everything was back to normal. Sometimes I didn't eat for a day or even weeks. I suffered for 13 years without any doctor saying a word about irritable bowel syndrome, I was the one that took it to my doctor and he put me on doxepin and within 24 hours I felt like a new person, can eat a normal diet and go where I want and live life again. Started with 25mg and only because it made me drowsy the second month I went to 10 mg, I love it! Thank You.

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January 18, 2013 12:13 PM
Review by Anonymous: User Rating:  
   
5.0

doxepin for Insomnia: Doxepin was prescribed to me by my neurologist as an adjunct therapy with Topamax for migraine prevention. I have only been on this for four months; two severe migraines! One trigger is lack of sleep. I have terrible insomnia. And if I do sleep, I sleep walk. Doxepin keeps me calm, migraine free, asleep and most of all I could have done with the weight gain.

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August 17, 2012 2:09 AM
Review by Anonymous (taken for 1 to 6 months): User Rating:  
   
9.0

doxepin for Depression: I started taking Doxepin for depression and insomnia. It seems to work good for both. I have not experienced any side effects so far.I had been taking Zoloft for depression and felt like a robot, no feelings at all. I take 2, 10mg at night about an hour before I'm ready to go to sleep. If I don't go to sleep, I take 1 more. So far I'm happy with the medicine as it works for depression and insomnia.

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July 12, 2012 11:35 PM
Review by Anonymous: User Rating:  
   
10

Silenor (doxepin) for Insomnia: This medication has been working well for me so far and I've tried them all. Glad it comes in 2 doses. I figure I can get good results with 3mg why bump up to 6mg. Side effects are nothing compared to others I have tried. I hope I don't get used to it but my doctor said it's not addicting.

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May 21, 2012 7:53 PM
Review by Anonymous: User Rating:  
   
9.0

Silenor (doxepin) for Insomnia: I had been on several medicines like Ambien and Lunesta. All of a sudden I needed a pill to sleep! Not only that but I was a walking zombie the next day. Mood swings were bad. My family became concerened. I switched to Silenor, not as potent but it did the trick.

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February 28, 2012 11:12 AM
Review by Anonymous: User Rating:  
   
10

doxepin for Insomnia: If you have trouble staying asleep, give Doxepin a try. It has worked wonders for me. I've experienced no side effects and it is non-addictive. The is often dispensed under the name Silenor in 3 and 6 mg doses.

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February 24, 2012 8:06 PM
Review by Anonymous: User Rating:  
   
10

Excellent sleep aid. I would get up in the middle of night two to three times. I had taken Ambien with terrible results (getting up and eating and not remembering things I did when I woke up). Tried Silenor and it helps me sleep during the night. I still may get up once to go to bathroom but go back to sleep right after that. Great medicine and recommend to any one who has trouble staying asleep.

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January 24, 2012 9:58 AM
Review by Anonymous: User Rating:  
   
8.0

Silenor (doxepin) for Insomnia: The medication works well, but the cost is to much. I can not afford this medication at all.

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January 18, 2012 10:37 PM
Review by Anonymous: User Rating:  
   
3.0

Silenor (doxepin): I have trouble falling asleep, and staying asleep. I have tried lunesta in the past and it didn't work. It put a terrible taste in my mouth for days. I have been on silenor for 3 nights now, and it isn't working for me. I took 6 mg at 9 pm, and was still awake at 3 am this morning, hadn't slept at all. It has been this way for all 3 nights. I have again developed a terrible taste in my mouth, so bad that I am going off this pill.

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January 7, 2012 11:51 AM
Review by susieqq: User Rating:  
   
1.0

doxepin for Insomnia: Was prescribed this medication (Doxepin 50mg) for sleep. It didn't even make me tired. Haven't been able to sleep since then. This just didn't work for me!

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January 4, 2012 2:13 PM
Review by can't sleep: User Rating:  
   
1.0

doxepin for Insomnia: I took this as prescribed (3 hours after eating, already in bed). It took me 90 minutes to go to sleep. I woke up 2 hours later and stayed up until 7 am in the morning (5 hours). I've got to have some strange biochemistry going on - Ambien gave me an anxiety attack and kept me up too. Both medicines seemed to depress my breathing rhythm.

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December 30, 2011 11:38 AM
Review by Anonymous: User Rating:  
   
5.0

doxepin for Insomnia: I give it a 5/10 because it worked for about 1-1/2 weeks and then I built up a tolerance (like I always do with all sleep medicines.. sighh..). I was on 10 mg. I bumped it up to 20 mg for about a week after the 10 mg lost its kick but still nothing. I had very vivid dreams those 2 weeks.. it almost felt like I wasn't sleeping deep enough the dreams were so vivid. But I had more energy during the day so it must have worked. It was nice to have my schedule back to "normal" for about a month (staying awake during the day). Now I've flip-flopped back to sleeping during the day again. I'm a chronic insomniac. My sleep specialist even jokes that I need a sledgehammer just to knock me out. I've tried just about every pill both over the counter and prescription.

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December 19, 2011 6:42 AM
Review by NCAnonymous: User Rating:  
   
6.0

Silenor (doxepin) for Insomnia: I have been using Ambien for several years and I seem to have built a tolerance so that I am no longer falling asleep nor staying asleep. (Note: I have used both Ambien and Ambien CR). I was on a "local" trip and had forgotten my Ambien, so I asked my Dr if she had samples of anything that would help me sleep. She gave me Silenor samples. While I was extremely happy with the sleep, I did wake up "hungover" and had a hard time getting moving. I also experienced very real hallucinations. Don't know if they will lessen with use, but I am going to ask for a months supply to see if it works out after an adjustment period.

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December 15, 2011 1:39 AM
Review by debhayley: User Rating:  
   
7.0

Silenor (doxepin) for Insomnia: This medicine did not work as well for me as Lunesta or Ambien, but I like that it is not addicting. It is definitely better than nothing. I did feel mildly hungover the next day.

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November 18, 2011 1:18 AM
Review by Anonymous: User Rating:  
   
1.0

Silenor (doxepin) for Insomnia: No matter what medication I take I only sleep between 4 - 6 hours before waking. After trying Silenor, I tossed and turned all night, waking up every few hours and felt a bit nauseous in the morning. I was so hopeful by all the good reviews on here, I figured I'd give it a shot.

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November 17, 2011 9:32 PM
Review by Anonymous: User Rating:  
   
2.0

Silenor (doxepin) for Insomnia: I was given samples of Silenor, and I've been taking it for about two weeks. My problem is not only that I can't sleep for more than 2 hours straight, but it also takes around 3 hours to fall asleep. Anyway, I noticed that I was getting a lot of terrible nightmares right away with the Silenor. As someone who hardly ever even remembers her dreams, the nightmares were quite obviously related to the medicine. Also, the Silenor didn't help me fall asleep/stay asleep at all. My doctor switched me to Ambien, and I'm trying that for the first time tonight. Most of you had a bad experience with Ambien and are loving the Silenor, so I'm not sure how this will work out.

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November 15, 2011 9:33 PM
Review by moehawk321: User Rating:  
   
9.0

doxepin for Insomnia: I have had insomnia off on and for 20 years and have been depressed for at least ten and have insomnia and anxiety. My doctor thought I was bipolar initially but has seen my problems concurrent, and we have dismissed mania. Doxepin works great. I was on Seroquel with many side effects, but I take 200mg of doxepin in two doses, and I take Klonopin, 1mg 3 times daily. I am a recovered drug addict and am very careful about abusable substances. This combination is perfect for people like me. The only side effect I have experienced is weight gain. In the first 3 months I began taking doxepin, I gained over 50 pounds but after several months my weight plateaued and is coming off with moderate exercise.

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November 1, 2011 5:14 PM
Review by Manny5067: User Rating:  
   
10

Silenor (doxepin) for Insomnia: The only medication that really works! I have tried Ambien and Lunesta and Silenor is superior to both of them.

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October 30, 2011 9:28 PM
Review by Anonymous: User Rating:  
   
9.0

doxepin for Insomnia: I've tried various medicine options. I take 10-20mg of generic doxepin per night now. I still wake up during the night but I fall back asleep much easier than before. I get 5-6 hours of good solid sleep per night which is great for me. The only time I have problems with drowsiness the next day is after I take 20mg at night.

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September 25, 2011 11:26 AM
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