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User Reviews for Diphenhydramine

Also known as: 40 Winks, Aler-Dryl, Aler-Tab, Alka-Seltzer Plus Allergy, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl, Benadryl Allergy, ...show all 96 brand names

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Diphenhydramine.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Motion Sickness 1 reviews 114 medications
   
8.8
Allergic Reactions 21 reviews 181 medications
   
8.1
Nausea/Vomiting 9 reviews 154 medications
   
7.8
Cold Symptoms 4 reviews 1030 medications
   
7.1
Insomnia 61 reviews 109 medications
   
7.0
Allergic Rhinitis 9 reviews 810 medications
   
6.8
Urticaria 5 reviews 183 medications
   
6.0
Cough 3 reviews 747 medications
   
5.7
Extrapyramidal Reaction 1 reviews 67 medications
   
5.5
Summary of Diphenhydramine reviews 114 reviews 7.0

Reviews for Diphenhydramine

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Benadryl (diphenhydramine) for Allergic Reactions: "Allergy reaction to nuts. Started feeling swelling around mouth, throat.... very scary, feel like I am stopping to breath. This instant relieve. Give it 10-15 minutes till kicks in. WORKS WONDERS. BUT.... you might need a good snooze after a good dose..."

   
10

Madam2 January 25, 2016

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For Insomnia: "Works quite well on insomnia but careful when combining with other meds that also work on your sympathetic/parasympathetic nervous system. I took it with lexapro and got significant problems with too low heart rate, respiratory issues and hypnic jerks."

   
7.0

avalokiteshwara (taken for less than 1 month) January 16, 2016

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Unisom SleepGels (diphenhydramine) for Insomnia: "This medication works well if taken as directed for your insomnia and for no longer than about 1 month. I began taking 1-50mg twice a week which worked very well but I continued to increase the dosage every 2 weeks. It did make me tired enough to fall right to sleep after about 45 minutes of taking it and with no drowsiness the following morning. "

   
7.0

Anonymous (taken for 2 to 5 years) January 15, 2016

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For Insomnia: "I take diphenhydramine in Ibuprofen PM to help me sleep, though I only take one pill and not more often than every third or fourth night. It works like a charm, enabling me to sleep without needing to get up and pee or waking up with my life concerns preventing a return to sleep, for 6-7 hours. My concern is whether it is habit-forming, whether taking this drug for sleep on some nights increases the difficulty I have in falling asleep without the drug, on other nights."

   
10

Steveplant January 14, 2016

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ZzzQuil (diphenhydramine) for Insomnia: "I purchased the zzzquil and it did not work not 1 bit , I would not recommended medication to anyone..."

   
1.0

BABYGIRL001 January 13, 2016

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Benadryl (diphenhydramine) for Nausea/Vomiting: "I get severe migraines and was given this in the hospital instead of traditional nausea meds. It work well and I now use it at home and actually works better than Zofran or Phenagren."

   
10

Mmwillis December 29, 2015

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Benadryl (diphenhydramine) for Nausea/Vomiting: "I got a severe back injury about 2 years ago. Couldn't function pain was so bad. So my doctor started putting me on codiene, then vicoden, then tramadol, and then so on but they all gave me hours of vomiting, gut wrenching cramps, and sweating. Read about benadryl being used to prevent this side effect. I took 3 25 mg tabs. I know that is one over recommended but I was desperate. 35 mins later I was sitting with my kids and not the trash can for the first time in a while. I can't believe I didn't figure this out sooner especially with a biotech degree."

   
10

A biotechnologist. (taken for less than 1 month) December 20, 2015

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Unisom SleepGels (diphenhydramine) for Insomnia: "Tried this after my new Dr took me off of Ambien that I'd been on for 3 1/2 years by a sleep Dr for my insomnia, I can stay wide awake for up to 48 hours & then if I do fall asleep only get between 2-6 hours of sleep. New Dr thinks I'm depressed BUT I'm far from that & keeps wanting to put me on depression medicine!! Called sleep Dr back in Iowa to tell new Dr here in Louisiana that I have insomnia which she did BUT new Dr doesn't believe sleep specialist!!"

   
1.0

Angeljennings (taken for 6 months to 1 year) December 20, 2015

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Simply Sleep (diphenhydramine) for Insomnia: "I have mixed feelings about this.. the first night I took it, it took about 1 and a half hours to kick in, and when it did my husband said I was acting like I was seriously drunk...which I remember very little of. I do remember it making me crazy itchy, and feeling like my skin was crawling. But, once I got in to bed, I knocked out and slept great and felt great in the morning. However, I took it last night around 930pm, and was up ALL night... I have to be up at 445a for work, and I fell asleep about 330 and just now feel like it's effects are kicking in. I may end up leaving work early because I feel so awful and tired. I dont know that I will take this again."

   
3.0

MissBrie November 30, 2015

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Benadryl (diphenhydramine) for Nausea/Vomiting: "I have Cyclic Vomiting Syndrome and take Benadryl everyday. It helps take the edge off. There are less side effects than other anti nausea medications and is safest for the body."

   
9.0

Andy D November 24, 2015

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For Nausea/Vomiting: "I tried everything yesterday to stop throwing up acid. I went from Nexium to Zantac to pepto to tums, nothing helped and it all just came back up an hour later. Thankfully my brother is a paramedic and told me about how they use benedryl for their nausea patients so I took 3 of the 25mg tablets and it worked!!"

   
10

Morgan Denee November 15, 2015

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For Allergic Rhinitis: "This is a wonderful drug for when my Allegra doesn't fully control my AR symptoms. It makes me feel sleepy and a bit dizzy, but it's totally worth it. Just don't take this drug if you have to drive anywhere."

   
9.0

FoxyFinn (taken for 1 to 6 months) October 21, 2015

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For Insomnia: "Diphenhydramine is an extremely effective sleep aid. It takes half an hour or less for 25 mg to knock me out. The biggest problem I have with diphenhydramine is that it makes me feel kinda' groggy and nauseous the next day. I feel like I'm walking around in some weird twilight and food just doesn't taste good to me. Still, out of the three sleeping pills I've tried, diphenhydramine is by far the most effective. Ambien made me feel like I was on a roller coaster and melatonin mainly makes me fall asleep a little faster."

   
8.0

FoxyFinn (taken for 1 to 6 months) October 20, 2015

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For Allergic Reactions: "Drowsiness is a reoccurring problem for me. I have difficulty focusing and end up passing out. The effect of the drug comes a little slowly depending on how severe my allergy attack is."

   
7.0

Anonymous (taken for 1 to 2 years) October 19, 2015

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Nytol (diphenhydramine) for Insomnia: "I have had problems sleeping lately. Someone recommend me to use these pill and they actually are really good. I have used them twice in a row and have slept well and even woke up when alarm came on."

   
10

Sanny1508 October 18, 2015

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For Insomnia: "took 100mg to fall asleep and slept walked in the middle of the night!!! I took a bottle of lotion out of the BATHROOM cabinet, and I must have watered it down and shook it up bc it was liquid the next day and sitting by my REFRIGERATOR!! wtf!! I have no memory of this.. and the next day I was anxious and depressed all over the place emotionally"

   
1.0

Anonymous October 14, 2015

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Benadryl (diphenhydramine) for Nausea/Vomiting: "I use it for nausea. It works wonders for me."

   
10

works! (taken for 10 years or more) October 2, 2015

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For Insomnia: "I dosed myself to sleep through the night for four nights in a row worked perfectly but when I stopped taking it I immediately started having post nasal drip (a lot of snot nonstop for two or three days). I also have hypertension"

   
10

mark187 September 25, 2015

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Sominex (diphenhydramine) for Insomnia: "Funnily enough, after taking this. I feel more easier to fell asleep during the day than in the night. After a unintentional 12 hours sleep( just couldn't wake myself up). Was awake for a few hours then was too drowsy and fell asleep again. Really feel these tablets works better during the day than in the night. : ("

   
5.0

Nickccc September 8, 2015

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For Insomnia: "The most effective and reasonable sleep aid I've taken. A single pill (25 mg) before bedtime will make me drowsy enough to fall asleep within a half hour, and it generally keeps me asleep throughout the night. Drowsiness the next day is a problem for me, however, if I take it too late in the previous night; it tends to stay in my system for quite a while and, as said in previous reviews, it's not something you should be taking every night. But it's still my go-to drug whenever I know that I need a good night's rest and I'll be able to sleep in the following morning."

   
8.0

Nobody's Hero September 4, 2015

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For Insomnia: "I took this as a sleeping aid due to a very hectic schedule that was stressing me out. It did help me go to sleep and stay asleep but I noticed that I was somewhat dizzy at times during the day. Over a six week period the dizziness became worse. I went to an ENT thinking perhaps I had an ear infection that was messing up my balance. He told me to discontinue the diphenhydramine and try valerian root (I didn't want to use any more drugs) and it would take time for the drug to get out of my system. I've been off the med for a week and still have some dizziness going on. This drug is definitely not for continuous use!"

   
5.0

RudyCoffee August 19, 2015

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Simply Sleep (diphenhydramine) for Insomnia: "I'm a little young to be needing sleeping pills, but I do sadly. (17 years old). I took the 2 small tablets, and I fell asleep around an hour later. But when I woke up I felt like complete crap as I was SO tired. I could barely get up to put my clothes on, and when I did, I felt a little dizzy, and I passed out which was the scariest thing. Tried them again just in case it wasn't the pills, happened again. So for now I'm going to stick to taking 1 instead of 2, and see if that helps any."

   
1.0

Anonymous July 5, 2015

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Sominex (diphenhydramine) for Insomnia: "Works for me in the same manner all the above have stated. Be aware, though, it is intended for occasional use, not nightly use. It's active ingredient is basically Benedryl, the same as in many allergy meds. If you check ingredient labels rather than going by the brand name, you may be able to find a bargain."

   
9.0

Gi-Savannah (taken for 1 to 6 months) June 26, 2015

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Simply Sleep (diphenhydramine) for Insomnia: "Very ineffective. Caused me to have a racing heart not sleep and to feel depressed and anxious the next day. Don't recommend"

   
1.0

Sandrajessica June 25, 2015

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Simply Sleep (diphenhydramine) for Insomnia: "This worked great for me! Full 8 hours sleep and woke up very refreshed with no drowsiness. However it did not work as well when used on long haul flight as i continually woke up. Still not much drowsiness though"

   
9.0

aus_kiwi May 31, 2015

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