User Reviews for Diphenhydramine

Also known as: 40 Winks, Aler-Dryl, Aler-Tab, Alka-Seltzer Plus Allergy, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl, Benadryl Allergy, Benadryl Children's Allergy, Benahist-10, Benahist-50, Benoject-50, Buckley's Bedtime, Bydramine, Calm-Aid, Complete Allergy Relief, Compoz Nighttime Sleep Aid, ConRx Allergy, Dicopanol, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Dormin, DPH, Dytan, Dytuss, Genahist, Help I Can't Sleep, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hyrexin, Miles Nervine, Nervine, Nightime Sleepaid, Nu-Med, Nytol, Nytol Caplet, Pardryl, PediaCare Children's Allergy, Pharbedryl, Q-Dryl, Q-Dryl A/F, Quenalin, Scot-Tussin Allergy, Siladryl, Siladryl Allergy, Siladryl DAS, Siladyl SA, Silphen Cough, Simply Sleep, Sleep, Sleep Tab II, Sleep Tabs, Sleep-ettes, Sleep-ettes D, Sleep-Eze-3, Sleepinal, Sleepwell 2-nite, Snooze Fast, Sominex, Sominex Maximum Strength Caplet, Somnicaps, Theraflu Thin Strips Multi Symptom, Total Allergy, Tranquil Nighttime Sleep Aid, Triaminic Thin Strips Allergy, Triaminic Thin Strips Cough & Runny Nose, Trux-adryl, Tusstat, Twilite, Uni-Tann, Unisom SleepGels, Unisom SleepMelts, Valu-Dryl, ZzzQuil

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Diphenhydramine.

Filter by:
Condition DownUp Reviews Compare Avg. Ratings DownUp
Pruritus 0 reviews 287 medications
   
9.0
Motion Sickness 1 reviews 109 medications
   
8.5
Allergic Reactions 16 reviews 183 medications
   
7.9
Cold Symptoms 3 reviews 823 medications
   
7.7
Insomnia 37 reviews 98 medications
   
7.4
Hay Fever 6 reviews 859 medications
   
6.3
Urticaria 4 reviews 183 medications
   
6.3
Nausea/Vomiting 3 reviews 152 medications
   
5.8
Cough 2 reviews 726 medications
   
5.0
Extrapyramidal Reaction 0 reviews 66 medications
   
2.0
Summary of Diphenhydramine reviews 72 reviews 7.3

Reviews for Diphenhydramine

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Review by cupcake02011 (taken for 6 months to 1 year): User Rating:  
   
10

diphenhydramine for Allergic Reactions: My doctor gave me this in 2010 when I first began having seasonal allergies. I thought it was the best allergy medication out there, like top notch stuff. Turns out its just a basic type of medication. No superpowers involved, but it works great you would think there are superpowers in them!

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May 3, 2013 9:08 PM
Review by Yeshus: User Rating:  
   
4.0

Sominex (diphenhydramine) for Insomnia: I have taken Sominex for a few days now and still wake up after 2-3 hours sleep and can't get back to sleep again. I am so tired. Yet I can fall asleep in the chair really easy in the day. I was hoping Sominex would work but so far it really hasn't.

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March 26, 2013 4:24 AM
Review by Daxton (taken for 6 months to 1 year): User Rating:  
   
8.0

Nightime Sleepaid (diphenhydramine) for Insomnia: My doctor had prescribed Ambien. Before taking it, I wanted to know side-effects. Found that it can have very negative unwanted side-effects. Therefore, did NOT even take one tablet. Threw them out! So, I turned to the Equate Nighttime Sleep aid, 50mg., which was a good choice. Help me to sleep well. I do, though, awake although briefly around 2:30-3:00 AM after having gong to bed at 9:00 PM. Notice some daytime sleepiness at times.

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March 17, 2013 11:37 AM
Review by astuder11: User Rating:  
   
9.0

Sominex (diphenhydramine) for Insomnia: I absolutely love Sominex. It works so great I fall asleep pretty fat and stay asleep which is so fantastic. Sometimes I wake up in the same position I fell asleep in. When I wake up it takes a few mins but once you start moving around you are fine.

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February 28, 2013 5:01 AM
Review by Anonymous (taken for less than 1 month): User Rating:  
   
9.0

Q-Dryl (diphenhydramine) for Allergic Reactions: Stopped the infernal itching (from poison ivy) within 15 minutes and dramatically reduced the spelling of the blisters.

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September 22, 2012 4:28 PM
Review by Kia N (taken for 5 to 10 years): User Rating:  
   
7.0

Sominex (diphenhydramine) for Insomnia: Sominex is a great night time sleep aide. One of the less costly options.

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August 16, 2012 4:27 PM
Review by Mama chic (taken for less than 1 month): User Rating:  
   
7.0

diphenhydramine for Allergic Reactions: It's a great medication except for the drowsy and sluggish effects.

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June 23, 2012 1:05 PM
Review by Anonymous: User Rating:  
   
7.0

Benadryl (diphenhydramine) for Nausea/Vomiting: I have emtophobia, that is, a pervasive fear of vomiting. I do not know if this affects vomiting, but if I feel nauseous, Benadryl works wonders. My stomach settles right down and my anxiety lowers just enough for me to deal with it without the use of benzodiazepines.

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June 15, 2012 10:24 PM
Review by benny d. reAl (taken for 10 years or more): User Rating:  
   
10

Benadryl (diphenhydramine) for Allergic Reactions: Relieves most allergy symptoms.

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May 22, 2012 1:33 AM
Review by Jen234 (taken for 6 months to 1 year): User Rating:  
   
8.0

Benadryl (diphenhydramine) for Allergic Reactions: I use this medicine for weather allergies and allergies to medications when I need it. It does help greatly but does not last long and my burning sensation comes back into my body and the hives start to show. However a lot of people say that this medicine makes them feel sedated. I have the complete opposite I take 1 before bed and I will not sleep.

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May 12, 2012 11:48 PM
Review by Anonymous: User Rating:  
   
9.0

Sominex (diphenhydramine) for Insomnia: As a former bartender, I'm a night owl by nature. Now that I'm in law school and have 8am classes, I can't afford to be up all night. It ruins my entire next day because I cannot think and I am useless. Also, lack of sleep depresses me and gives me anxiety. Anyhow, I have tried literally everything under the sun- Ambien, Sleepy time, Valerian, melatonin, Simply sleep, and 4-5 others, both natural and not, and Sominex is the only one that has ever consistently worked to not only put me to sleep, but KEEP me asleep, on most nights. Occasionally I'll have an off night when I wake up mid-sleep or when I'm super groggy in the morning, but at least 90% of the time it works great. I usually take it about 1-2.5 hours before I want to fall asleep.

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April 14, 2012 1:10 AM
Review by Anonymous: User Rating:  
   
2.0

Benadryl (diphenhydramine) for Nausea/Vomiting: Didn't seem to work very well for me.

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April 12, 2012 10:37 AM
Review by AllergySufferer: User Rating:  
   
7.0

Benadryl (diphenhydramine) for Allergic Reactions: Works well and is one of my to go-to antihistamines. However it is very sedating and is also not long-lasting. It would work great for someone with insomnia as a milder sleep-aid, but for my use I would say that it works, but makes you sedated.

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March 14, 2012 9:01 PM
Review by Anonymous: User Rating:  
   
6.0

Sominex (diphenhydramine) for Insomnia: This works much better than anything. It made me stay asleep longer as well.

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March 5, 2012 5:09 PM
Review by Anonymous: User Rating:  
   
9.0

Benadryl (diphenhydramine) for Cough: Variant asthma, chronic, have been on many antihistamines and other costly asthma medicines over the years. I began taking Benadryl in late November 2011. Taking 25 mg after awakening in the morning followed an hour or so later with 25 mg with another 25mg early afternoon (when symptoms occur) and 25 mg prior to bedtime in conjunction with Symbicort twice/day. I have a much improved quality of life and am beginning to have some control over the chronic cough.

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January 7, 2012 4:24 PM
Review by hscolnik: User Rating:  
   
8.0

Benadryl (diphenhydramine) for Insomnia: I have used it on and off for years to help me sleep in the day (I work 3rd shift) and it is consistently helpful.

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November 26, 2011 5:33 AM
Review by Anonymous:

Unisom SleepGels (diphenhydramine) for Insomnia: Have tried all sorts of prescription medicine from my doctor, but found these worked so well.

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November 18, 2011 8:10 PM
Review by don8841: User Rating:  
   
10

Sominex (diphenhydramine) for Insomnia: I take it 3 or 4 times a week and it works well. Full night's sleep. A little drowsy when I wake up but it passes after my morning coffee. I love it.

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November 18, 2011 10:30 AM
Review by RipTheSystem: User Rating:  
   
9.0

Benadryl Allergy (diphenhydramine) for Hay Fever: I have severe seasonal allergies as well as severe allergies to dust and mold. I had gone through the gamut of second generation antihistamines (Claritin, Zyrtec and Allegra) with minimal success in treating my extreme symptoms. I decided to try the first generation antihistamine: Benadryl. Of course, it's been around for a long time, but it's definitely the most effective. The drawback to this older antihistamine is that it causes sleepiness, and it's not slight. Also, the newer antihistamines can be taken once a day, while Benadryl doses last only 4-6 hours. But to this extreme allergy sufferer, it's a small tradeoff, because it certainly treats the symptoms far better.

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October 20, 2011 11:34 PM
Review by Anonymous: User Rating:  
   
9.0

Benadryl (diphenhydramine) for Hay Fever: I absolutely love Benadryl. It's works fast when I need it and relieves the symptoms enough to make me feel comfortable. It does make me sleepy so I take it at night. I do take it during the day occasionally when I know I don't have to drive anywhere.

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September 5, 2011 12:55 AM
Review by Anonymous: User Rating:  
   
2.0

Benadryl (diphenhydramine) for Hay Fever: I took this medicine for the first time in my life when I was 19 years old. It didn't work, it gave me the worst side effects ever. Upset stomach, bad headache, body cramps, and dizziness.

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August 29, 2011 12:47 AM
Review by yvonne11: User Rating:  
   
9.0

Benadryl (diphenhydramine) for Cold Symptoms: I have a very bad cold and not getting much sleep. Took two Benadryl and feel much better.

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May 9, 2011 12:55 AM
Review by Anonymous: User Rating:  
   
5.0

40 Winks (diphenhydramine) for Insomnia: In a lower dose of 25mg it made it easier to wake up in the morning and increased my appetite but in the higher dose of 50mg I got headaches, lost my appetite, and my sleep got even more messed up.

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February 24, 2011 3:10 AM
Review by Anonymous: User Rating:  
   
10

Benadryl (diphenhydramine) for Cold Symptoms: Very good to dry up the drainage that makes that tickling in your throat.

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February 19, 2011 10:26 AM
Review by mac1681: User Rating:  
   
8.0

diphenhydramine for Insomnia: I use this instead of Xanax. It works and has no hangover effect. My concern, however, is that a thrombophlebitis might have been the result of more that a month's moderate usage. I did go to the hospital where lab work was done and a wet-scan ultra-sound was done, with no evidence of clotting. I will continue to use it because it's more effective than any other product.

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November 2, 2010 9:54 AM
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