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Medications for Pruritus

Drugs associated with Pruritus

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Pruritus: 1. Itching, an unpleasant cutaneous sensation that provokes the desire to rub or scratch the skin to obtain relief.

2. Any of various conditions marked by itching, the specific site or type being indicated by a modifying term.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
hydroxyzine Rx N N X 22 reviews
7.0

Generic name: hydroxyzine systemic

Brand names:  Atarax, Vistaril, Hyzine

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Atarax Rx N N X 5 reviews
8.0

Generic name: hydroxyzine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Benadryl Rx/OTC B N X Add review
9.0

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
diphenhydramine Rx/OTC B N X Add review
9.0

Generic name: diphenhydramine systemic

Brand names:  Benadryl, Benadryl Allergy, Banophen, Diphenhist, Allermax, Ben-Tann, Benadryl Children's Allergy, Complete Allergy Relief, Dicopanol, Diphedryl, Dytan, Dytuss, Scot-Tussin Allergy, Silphen Cough, Twilite, Valu-Dryl

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Vistaril Rx N N X Add review
8.0

Generic name: hydroxyzine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Zofran Off Label Rx B N Add review Add

Generic name: ondansetron systemic

Drug class: 5HT3 receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Benadryl Allergy Rx/OTC B N X Add review Add

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

 
AmLactin Rx/OTC B N Add review Add

Generic name: ammonium lactate topical

Drug class: topical emollients

For consumers: dosage, side effects

 
gabapentin Off Label Rx C N X 1 review
10

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
hydrocortisone Rx/OTC C N 3 reviews
7.0

Generic name: hydrocortisone topical

Brand names:  Anucort-HC, Cortizone-10, Ala-Cort, Hytone, Locoid, Proctosol-HC, Proctozone HC, Westcort, Ala-Scalp, Ala-Scalp HP, Anumed-HC, Aqua Glycolic HC, Aquanil HC, Beta HC, Bioelements Immediate Comfort, Caldecort, Cetacort, Cortaid, Cortaid Maximum Strength, Cortalo with Aloe, Corticaine, Cortizone-5, Cortizone-10 Anal Itch Cream, Cotacort, Dermarest Plus Anti-Itch, Dermasorb HC, Dermtex HC, Gly-Cort, Gynecort Maximum Strength, Hemorrhoidal HC, Hemril-30, Hemril-HC Uniserts, Hydrocortisone with Aloe, Instacort, Itch-X Lotion, Keratol HC, Lacticare-HC, Locoid Lipocream, Nutracort, Pandel, Pediaderm HC, Procto-Kit 1%, Procto-Kit 2.5%, Procto-Pak 1%, ProctoCare-HC, Proctocort, Proctocream-HC, Proctosert HC, Proctozone-H, Recort Plus, Rectasol-HC, Sarnol-HC, Scalacort, Scalp-Cort, Scalpicin, Texacort, U-Cort

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
ondansetron Off Label Rx B N Add review Add

Generic name: ondansetron systemic

Brand names:  Zofran, Zofran ODT

Drug class: 5HT3 receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Anucort-HC Rx/OTC C N Add review Add

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Banophen Rx/OTC B N X Add review Add

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

 
cyproheptadine Rx B N X Add review
9.0

Generic name: cyproheptadine systemic

Drug class: antihistamines

For consumers: interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
ammonium lactate Rx/OTC B N Add review
9.0

Generic name: ammonium lactate topical

Brand names:  AmLactin, Lac-Hydrin, Geri-Hydrolac, Kerasal AL, Laclotion

Drug class: topical emollients

For consumers: dosage, side effects

For professionals: Prescribing Information

 
Cortizone-10 Rx/OTC C N 1 review
10

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

 
lidocaine Rx/OTC B N Add review Add

Generic name: lidocaine topical

Brand names:  Xylocaine Jelly, AneCream, AneCream with Tegaderm, Anestacon, Anestafoam, Bactine, CidalEaze, LidaMantle, Lidocream, Lidopin, LidoRx, LidoRxKit, Lidosense 5, Lidovex, Lidozol, LMX 4, Medi-Quik Spray, Regenecare HA Spray, Senatec, Xylocaine Topical

Drug class: topical anesthetics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Zofran ODT Off Label Rx B N Add review Add

Generic name: ondansetron systemic

Drug class: 5HT3 receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Lac-Hydrin Rx/OTC B N Add review Add

Generic name: ammonium lactate topical

Drug class: topical emollients

For consumers: dosage, side effects

For professionals: Prescribing Information

 
Xylocaine Jelly Rx/OTC B N Add review Add

Generic name: lidocaine topical

Drug class: topical anesthetics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Ala-Cort Rx/OTC C N Add review Add

Generic name: hydrocortisone topical

Drug class: topical steroids

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
calamine OTC N N 2 reviews
9.0

Generic name: calamine topical

Brand name:  Calamine Plain

Drug class: miscellaneous topical agents

For consumers: side effects

 
Diphenhist Rx/OTC B N X Add review Add

Generic name: diphenhydramine systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics, antihistamines, anticholinergic antiemetics, anticholinergic antiparkinson agents

For consumers: dosage, interactions, side effects

 
diphenhydramine OTC B N Add review Add

Generic name: diphenhydramine topical

Brand names:  Derma-Pax, Dermarest

Drug class: topical antihistamines

For consumers: interactions, side effects

For professionals: A-Z Drug Facts

 
doxepin Rx B N X 1 review
9.0

Generic name: doxepin topical

Brand names:  Prudoxin, Zonalon

Drug class: topical antihistamines

For consumers: interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
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Topics under Pruritus

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): Itching; Itchy Skin

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