Hydroxyzine Side Effects
Some side effects of hydroxyzine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to hydroxyzine: oral capsules, oral suspension or solution, parenteral injection
Side effects include:
Drowsiness, dry mouth.
For Healthcare Professionals
Applies to hydroxyzine: compounding powder, intramuscular solution, oral capsule, oral suspension, oral syrup, oral tablet
Nervous system side effects have included moderate to slight drowsiness. This effect is usually transitory and may disappear with continued therapy or upon discontinuation of the agent. Headache, fatigue, depression, insomnia, sedation, and nervousness have also been reported with hydroxyzine. With higher than recommended doses of hydroxyzine, involuntary motor activity such as tremor and convulsions have been reported in rare instances.
Gastrointestinal side effects have included dry mouth (most common side effect), nausea, diarrhea, abdominal pain, and increases in weight and appetite.
Respiratory side effects have included the thickening of bronchial secretions. Rare occurrences of pharyngitis, bronchospasm, and epistaxis have also been reported.
Cardiovascular side effects have included palpitations, hypotension, and edema.
Dermatologic side effects have included angioedema, photosensitivity, and rash.
Genitourinary side effects have included rare cases of urinary retention and prolonged penile erections.
Ocular side effects have included blurred vision.
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