Drug Information
Side Effects > Hydroxyzine

Hydroxyzine Side Effects

Brand Names: Atarax, Vistaril, Atarax

Please note - some side effects for Hydroxyzine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).


For the consumer

For the professional

By body system

Side Effects of Hydroxyzine - for the consumer


Hydroxyzine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Hydroxyzine:

Drowsiness; dry mouth.

Seek medical attention right away if any of these SEVERE side effects occur when using Hydroxyzine:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); involuntary movements.


Hydroxyzine Capsules

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Hydroxyzine Capsules:

Drowsiness; dry mouth.

Seek medical attention right away if any of these SEVERE side effects occur when using Hydroxyzine Capsules:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); involuntary movements.


Hydroxyzine Suspension

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Hydroxyzine Suspension:

Drowsiness; dry mouth.

Seek medical attention right away if any of these SEVERE side effects occur when using Hydroxyzine Suspension:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); involuntary movements.


Hydroxyzine Syrup

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Hydroxyzine Syrup:

Drowsiness; dry mouth.

Seek medical attention right away if any of these SEVERE side effects occur when using Hydroxyzine Syrup:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); involuntary movements.

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For the professional


Hydroxyzine

Side effects reported with the administration of Hydroxyzine pamoate are usually mild and transitory in nature.

Anticholinergic

Dry mouth.

Central Nervous System

Drowsiness is usually transitory and may disappear in a few days of continued therapy or upon reduction of the dose. Involuntary motor activity including rare instances of tremor and convulsions have been reported, usually with doses considerably higher than those recommended. Clinically significant respiratory depression has not been reported at recommended doses.

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Hydroxyzine Capsules

Side effects reported with the administration of Hydroxyzine pamoate are usually mild and transitory in nature.

Anticholinergic: Dryness of the mouth may occur.

Central Nervous System: Drowsiness is usually transitory and may disappear in a few days of continued therapy or upon reduction of the dose.  Involuntary motor activity, including rare instances of tremor and convulsions, have been reported, usually with doses considerably higher than those recommended. Clinically significant respiratory depression has not been reported at recommended doses.

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Hydroxyzine Injection

Therapeutic doses of Hydroxyzine seldom produce impairment of mental alertness. However, drowsiness may occur; if so, it is usually transitory and may disappear in a few days of continued therapy or upon reduction of the dose. Dryness of the mouth may be encountered at higher doses. Extensive clinical use has substantiated the absence of toxic effects on the liver or bone marrow when administered in the recommended doses for over four years of uninterrupted therapy. The absence of adverse effects has been further demonstrated in experimental studies in which excessively high doses were administered.

Involuntary motor activity, including rare instances of tremor and convulsions, has been reported, usually with doses considerably higher than those recommended. Continuous therapy with over one gram per day has been employed in some patients without these effects having been encountered.

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Hydroxyzine Oral Solution

Side effects reported with the administration of Hydroxyzine HCl Oral Solution are usually mild and transitory in nature.

Anticholinergic:

Dry mouth.

Central Nervous System:

Drowsiness is usually transitory and may disappear in a few days of continued therapy or upon reduction of the dose. Involuntary motor activity including rare instances of tremor and convulsions have been reported, usually with doses considerably higher than those recommended. Clinically significant respiratory depression has not been reported at recommended doses.

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By body system


Nervous system side effects

Nervous system side effects have included moderate to slight drowsiness. This effect is usually transitory and may disappear with continued therapy or upon discontinuation of the agent. Headache, fatigue, depression, insomnia, sedation, and nervousness have also been reported with hydroxyzine. With higher than recommended doses of hydroxyzine, involuntary motor activity such as tremor and convulsions have been reported in rare instances.


Gastrointestinal side effects

Gastrointestinal side effects have included dry mouth (most common side effect), nausea, diarrhea, abdominal pain, and increases in weight and appetite.


Respiratory side effects

Respiratory side effects have included the thickening of bronchial secretions. Rare occurrences of pharyngitis, bronchospasm, and epistaxis have also been reported.


Cardiovascular side effects

Cardiovascular side effects have included palpitations, hypotension, and edema.


Dermatologic side effects

Dermatologic side effects have included angioedema, photosensitivity, and rash.


Genitourinary side effects

Genitourinary side effects have included rare cases of urinary retention and prolonged penile erections.


Ocular side effects

Ocular side effects have included blurred vision.

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More resources:

Drugs.com Atarax

Drugs.com Vistaril

PDR Atarax

MedFacts Atarax

MedFacts Hydroxyzine

Micromedex Hydroxyzine - Includes detailed dosage instructions.

FDA Vistaril

FDA Hydroxyzine

FDA Atarax

Facts & Comparisons Hydroxyzine

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