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Vetivex Hartmann's Solution for Injection

This page contains information on Vetivex Hartmann's Solution for Injection for veterinary use.
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  • Vetivex Hartmann's Solution for Injection Indications
  • Warnings and cautions for Vetivex Hartmann's Solution for Injection
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Vetivex Hartmann's Solution for Injection

This treatment applies to the following species:
Manufacturer: Dechra

For Animal Use Only

Description

Hartmann’s Solution is a sterile, nonpyrogenic solution for fluid and electrolyte replenishment in single dose containers for parenteral administration. It contains no antimicrobial agents.

Each 100 ml of solution contains:

Sodium chloride

600 mg

Sodium lactate

317 mg

Potassium chloride

40 mg

Calcium chloride dihydrate

27 mg


Electrolyte concentrations

mmol/L

mEq/L

Sodium

131

131

Potassium

5

5

Calcium

2

4

Chloride

111

111

Lactate

29

29

Clinical Pharmacology

Hartmann’s Solution has value as a source of water and electrolytes. It is capable of inducing diuresis depending on the clinical condition of the patient.

Hartmann’s Solution produces a metabolic alkalinizing effect. Lactate ions are metabolized ultimately to carbon dioxide and water, which requires the consumption of hydrogen cations.

Vetivex Hartmann's Solution for Injection Indications and Usage

Hartmann’s Solution is indicated as a source of water and electrolytes or as an alkalinizing agent.

Warnings

Do not administer to horses by intraperitoneal injection.

Hartmann’s Solution should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency, and in clinical states in which there exists edema with sodium retention.

Hartmann’s Solution should be used with great care, if at all, in patients with hyperkalemia, severe renal failure, and in conditions in which potassium retention is present.

Hartmann’s Solution should be used with great care in patients with metabolic or respiratory alkalosis.

The administration of lactate ions should be done with great care in those conditions in which there is an increased level or an impaired utilization of these ions, such as severe hepatic insufficiency.

Hartmann’s Solution should not be administered simultaneously with blood through the same

administration set because of the likelihood of coagulation.

The parenteral administration of Hartmann’s Solution can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states, or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injections. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of the injections.

In patients with diminished renal function, administration of Hartmann’s Solution may result in sodium or potassium retention.

Hartmann’s Solution is not for use in the treatment of lactic acidosis.

Adverse Reactions

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, and hypervolemia. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Precautions

Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations, and acid base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation.

Hartmann’s Solution must be used with caution. Excess administration may result in metabolic alkalosis.

Do not administer unless solution is clear and seal is intact.

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, and hypervolemia.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Dosage and Administration

As directed by a veterinarian. Dosage is dependent upon the age, weight and clinical condition of the patient as well as laboratory determinations.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

All solutions for injection contained in plastic containers are intended for administration using aseptic technique.

Additives may be incompatible. Complete information is not available. Those additives known to be incompatible should not be used. Consult with pharmacist, if available. If, in the informed judgment of the veterinarian, it is deemed advisable to introduce additives, use aseptic technique. Mix thoroughly when additives have been introduced. Do not store solutions containing additives. Discard unused portion.

Overdosage:

In an event of overhydration or solute overload, re-evaluate the patient and institute appropriate corrective measures. See Warnings, Adverse Reactions and Precautions.

How Supplied

Hartmann’s Solution is supplied as:

NDC Code

Volume

17033-482-01

1000 mL

17033-482-05

5000 mL

Storage

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.

CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

DISTRIBUTED BY: Dechra Veterinary Products, 7015 College Boulevard, Suite 525, Overland Park, KS 66211

Made in Northern Ireland.

For a copy of the Material Safety Data Sheet (MSDS) or to report adverse reactions call Dechra Veterinary Products at (866) 933-2472.

© 2015 Dechra Ltd.

LEAFV11J/0

NAC No.: 1459083.0

DECHRA VETERINARY PRODUCTS
7015 COLLEGE BLVD., STE. 525, OVERLAND PARK, KS, 66211
Telephone:   913-327-0015
Toll-Free:   866-933-2472
Fax:   913-327-0016
Website:   www.dechra-us.com
Every effort has been made to ensure the accuracy of the Vetivex Hartmann's Solution for Injection information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2016 North American Compendiums. Updated: 2016-10-31

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