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Safe-Guard Beef and Dairy Cattle Dewormer (290 g)

This page contains information on Safe-Guard Beef and Dairy Cattle Dewormer (290 g) for veterinary use.
The information provided typically includes the following:
  • Safe-Guard Beef and Dairy Cattle Dewormer (290 g) Indications
  • Warnings and cautions for Safe-Guard Beef and Dairy Cattle Dewormer (290 g)
  • Direction and dosage information for Safe-Guard Beef and Dairy Cattle Dewormer (290 g)

Safe-Guard Beef and Dairy Cattle Dewormer (290 g)

This treatment applies to the following species:
Company: Intervet/Merck Animal Health


290 g Paste 10% (100 mg/g)

for Beef & Dairy Cattle

One tube deworms 12 (1,000 lb) cattle or 58 animals of 220 lb each.

To be used only with Safe-Guard® dosing equipment.

Safe-Guard Beef and Dairy Cattle Dewormer (290 g) Indications

For the treatment and control of: Lungworms: Adult Dictyocaulus viviparus; Stomach worms: Adult brown stomach worms (Ostertagia ostertagi), Adult and fourth stage larvae barberpole worms (Haemonchus contortus), fourth stage larvae barberpole worms (H. placei), and Adult and fourth stage larvae small stomach worms (Trichostrongylus axei); Intestinal worms (Adult and fourth stage larvae): hookworms (Bunostomum phlebotomum), thread-necked intestinal worms (Nematodirus helvetianus), small intestinal worms (Cooperia punctata & C. oncophora), bankrupt worms (Trichostrongylus colubriformis), and nodular worms (Oesophagostomum radiatum).


Safe-Guard® Paste is given orally to beef and dairy cattle. The dose is 2.3 mg fenbendazole/lb (5 mg/kg) of body weight or 5 g Safe-Guard® Paste per 220 lb body weight (100 kg). Each full depression of the dispensing gun trigger delivers approximately 5 g Safe-Guard® Paste. Do not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance.

Directions For Use

This cartridge is intended for use only with the dispensing gun designed for this product. To prepare dispensing gun for administration of paste:

1. Turn plunger rod so that notches face up and retract rod fully.

2. Insert cartridge and ring into gun handle until flush with rubber gasket. Turn cartridge and ring clockwise to secure cartridge to gun.

3. Push plunger rod forward until firm contact is made with cartridge plunger.

4. Turn plunger rod so that notches face downward.

5. Remove cap from cartridge.

6. Depress trigger until paste has been ejected. Discard ejected paste. This is to ensure a full initial dose.

7. One full depression of trigger delivers one dose for a 220 lb animal.

8. Insert nozzle through the interdental space and deposit paste on back of the tongue by depressing the trigger for the appropriate number of depressions as determined from the table.

Administer according to the following table:

Cattle Weight

No. of Depressions

One Tube Will Treat

220 lb


58 head

440 lb


29 head

660 lb


19 head

880 lb


14 head

1100 lb


11 head

1540 lb


8 head


NOT FOR USE IN HUMANS. KEEP OUT OF REACH OF CHILDREN. The Safety Data Sheet (SDS) contains more detailed occupational safety information. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDAVETS, or

Withdrawal Periods and Residue Warnings: Milk taken during treatment and for 96 hours after the last treatment must not be used for human consumption.

Cattle must not be slaughtered for human consumption within 8 days following last treatment with this drug product.

Not for use in beef calves less than 2 months of age, dairy calves, and veal calves. A withdrawal period has not been established for this product in pre-ruminating calves.

OTHER WARNINGS: Parasite resistance may develop to any dewormer, and has been reported for most classes of dewormers. Treatment with a dewormer used in conjunction with parasite management practices appropriate to the geographic area and the animal(s) to be treated may slow the development of parasite resistance. Fecal examinations or other diagnostic tests and parasite management history should be used to determine if the product is appropriate for the herd, prior to the use of any dewormer. Following the use of any dewormer, effectiveness of treatment should be monitored (for example, with the use of a fecal egg count reduction test or another appropriate method). A decrease in a drug’s effectiveness over time as calculated by fecal egg count reduction tests may indicate the development of resistance to the dewormer administered. Your parasite management plan should be adjusted accordingly based on regular monitoring.

Restricted drug (California) - use only as directed.

Store at or below 25°C (77°F).


Fenbendazole (active ingred.) made in China. Formulated in France.

Distributed by:

Intervet Inc. (d/b/a Merck Animal Health), Madison, NJ 07940

Approved by FDA under NADA # 132-872

©2020 Intervet Inc., a subsidiary of Merck & Co. Inc.

Rev. 09/2020

Net Weight


290 g (10.2 oz)

369602 R4

364821 R4

CPN: 1047393.3

Intervet Inc.

Customer Service:   800-521-5767
Order Desk:   800-648-2118
Technical Service (Companion Animal):   800-224-5318
Technical Service (Livestock):   800-211-3573
Fax:   973-937-5557
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Copyright © 2023 Animalytix LLC. Updated: 2023-11-27