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This page contains information on Bursine-2 for veterinary use.
The information provided typically includes the following:
  • Bursine-2 Indications
  • Warnings and cautions for Bursine-2
  • Direction and dosage information for Bursine-2


This treatment applies to the following species:
Company: Zoetis

Bursal Disease Vaccine

Live Virus

Read in full, follow directions carefully.

For Veterinary Use Only.

Store in the dark at 2° to 7°C (35° to 45°F).

Do not vaccinate within 21 days before slaughter.

Use entire contents of vial when first opened.

Burn vaccine container and all unused contents.

Bursine-2 Caution

Use only in states where permitted and on premises with a history of infectious bursal disease.

For drinking-water administration

Bursine®-2 is a live virus vaccine to aid in the prevention of infectious bursal disease (IBD or Gumboro disease) of chickens.

Bursine-2 is particularly suited for use in flocks where maternal antibodies have interfered in active immunization using the milder live virus vaccines.


Chickens: Vaccinate healthy chickens via the drinking water at 7 days of age or older.

Breeders: When used as a primer for an inactivated IBD vaccine, Bursine-2 should be administered via the drinking water 6 to 8 weeks prior to administration of an inactivated product.

Directions For Use

1. Discontinue use of medications or sanitizing agents in the drinking water 24 hours before vaccinating. Do not resume use for 24 hours following vaccination.

2. Water used for the drinking water administration of a live virus vaccine must be non-chlorinated.

3. Provide enough waterers so two-thirds of the birds may drink at one time. Scrub waterers with fresh, clean, non-chlorinated water and use no disinfectants. Let waterers drain dry.

4. Turn off automatic waterers, so the only available water is the vaccine water. Do not give vaccine water through medication tanks.

5. Withhold water for 2 to 4 hours before vaccinating. Do not deprive the birds of water if the temperature is extremely high.

6. Remove seal from vaccine vial.

7. Remove stopper and half-fill vial with clean, cool, non-chlorinated water.

8. Replace stopper and shake until dissolved.

9. Use a clean container two thirds filled with cool, clean, non-chlorinated water. Add dried milk at the rate of one ounce (28.4 gm) per 2 U.S. gallons (7.6 liters). Use 1-2 gallons (3.8-7.6 liters) of this solution for 1,000 doses of vaccine.

10. Add the rehydrated vaccine to the powdered milk solution and stir thoroughly.

11. Distribute the final volume of vaccine water evenly among the clean waterers. Do not place the waterers in direct sunlight. Resume regular water administration only after all the vaccine water has been consumed.

Bursine-2 Caution

This product should be stored, transported, and administered in accordance with the instructions and directions. Use only in states where permitted and on premises with a history of infectious bursal disease.

Contains gentamicin as a preservative.


Keep a record of vaccine serial number and expiration date, date of receipt and date of vaccination, where vaccination takes place, and any reactions observed.


List No. 1510522000: 10 x 1,000 Doses

1510526000: 10 x 5,000 Doses

1510528000: 10 x 10,000 Doses

1510529000: 25,000 Doses

U.S. Vet. License No. 190

Zoetis Inc., Kalamazoo, MI 49007, USA

13855200, 13865600

CPN: 3690277.3

Telephone:   269-359-4414
Customer Service:   888-963-8471
Every effort has been made to ensure the accuracy of the Bursine-2 information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2022 Animalytix LLC. Updated: 2021-11-29