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Mayzent: 7 things you should know

Medically reviewed by Carmen Pope, BPharm. Last updated on July 3, 2023.

1. How it works

2. Upsides

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Mayzent is an S1P receptor modulator that may be used to treat relapsing forms of multiple sclerosis in adults. It is only suitable for people with a certain CYP2C9 genetic type and genotype testing must be carried out before initiation. Some people may require monitoring for at least 6 hours after the first dose of Mayzent because it can cause slowing of the heart rate and cardiac conduction abnormalities.

5. Tips

6. Response and effectiveness

7. Interactions

Medicines that interact with Mayzent may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Mayzent. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Mayzent interacts with over 500 medications; the majority of these interactions are considered major. Common medications that may interact with Mayzent include:

Mayzent has not been studied in people taking QT-prolonging medications, such as citalopram, chlorpromazine, haloperidol, methadone, or erythromycin. Initiation of Mayzent treatment results in a decreased heart rate which may prolong the QT interval. Use of Class Ia (eg, quinidine, procainamide) and Class III medications (such as amiodarone or sotalol) has been associated with cases of Torsades de Pointes in patients with bradycardia. Consult with a cardiologist.

Mayzent may have additive immune-suppressing effects when given with any other medications such as anticancer drugs, immune-modulating, or immunosuppressive therapies, which may increase a person's risk for infection. Take this into account when switching from drugs with prolonged immune effects, such as natalizumab, teriflunomide, or mitoxantrone.

Note that this list is not all-inclusive and includes only common medications that may interact with Mayzent. You should refer to the prescribing information for Mayzent for a complete list of interactions.


Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Mayzent only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2024 Revision date: July 3, 2023.