Skip to main content

Bendeka: 7 things you should know

Medically reviewed by Carmen Pope, BPharm. Last updated on June 20, 2023.

1. How it works

2. Upsides

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Bottom Line

Bendeka is a cytotoxic agent that must be administered by a health professional and may be used to treat chronic lymphocytic leukemia (CLL) and a certain type of non-Hodgkin lymphoma. It can cause serious side effects such as severe myelosuppression, liver toxicity, and infusion site reactions. Effective contraception should be used during treatment because Bendeka can cause harm to a developing baby and it may impair fertility in males. Response rates of 59% for CLL and 74% for NHL have been reported.

5. Tips

6. Response and effectiveness

7. Interactions

Medicines that interact with Bendeka may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Bendeka. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with Bendeka include:

Coadministration with CYP1A2 inhibitors, such as ciprofloxacin, enoxacin, or fluvoxamine may increase the risk of side effects of Bendeka. Coadministration with CYP1A2 inducers, such as phenytoin, rifampin, ritonavir, or smoking may decrease the effectiveness of Bendeka.

Note that this list is not all-inclusive and includes only common medications that may interact with Bendeka. You should refer to the prescribing information for Bendeka for a complete list of interactions.


Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Bendeka only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2024 Revision date: June 20, 2023.