Zontivity Side Effects

Generic name: vorapaxar

Medically reviewed by Drugs.com. Last updated on Aug 24, 2024.

Note: This document provides detailed information about Zontivity Side Effects associated with vorapaxar. Some dosage forms listed on this page may not apply specifically to the brand name Zontivity.

Applies to vorapaxar: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

This medicine may increase your risk of serious bleeding problems. Call your doctor right away if you have bleeding that is severe or that you cannot control, coughing up blood, pink, red, or brown urine, red or black stools, or vomiting blood or material that looks like coffee grounds.

This medicine can cause you to bleed and bruise more easily. Take precautions to avoid injury. Brush and floss your teeth gently, do not play rough sports, and be careful with sharp objects.

Do not Stop taking vorapaxar (the active ingredient contained in Zontivity) without checking first with your doctor.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.

Serious side effects of Zontivity

Along with its needed effects, vorapaxar may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking vorapaxar:

Other side effects of Zontivity

Some side effects of vorapaxar may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to vorapaxar: oral tablet.

General adverse events

Bleeding, including life-threatening and fatal bleeding, is the most commonly reported adverse reaction.^[Ref]

Hematologic

• Very common (10% or more): Bleeding
• Common (1% to 10%): Anemia, iron deficiency^[Ref]

Dermatologic

• Common (1% to 10%): Rashes, eruptions, exanthemas^[Ref]

Gastrointestinal

• Common (1% to 10%): Gastrointestinal bleeding^[Ref]

Ocular

• Common (1% to 10%): Retinopathy or retinal disorder, diplopia/oculomotor disturbances^[Ref]

Nervous system

• Uncommon (0.1% to 1%): Intracranial bleeding^[Ref]

See also:

Further information

Zontivity side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer