Zontivity Side Effects
Generic Name: vorapaxar
Note: This page contains side effects data for the generic drug vorapaxar. It is possible that some of the dosage forms included below may not apply to the brand name Zontivity.
Common side effects of Zontivity include: hemorrhage. Other side effects include: anemia and gastrointestinal hemorrhage. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to vorapaxar: oral tablet
As well as its needed effects, vorapaxar (the active ingredient contained in Zontivity) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking vorapaxar, check with your doctor immediately:Less common:
- Bloody or black, tarry stools
- pale skin
- severe stomach pain
- troubled breathing with exertion
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting of blood or material that looks like coffee grounds
- headache, sudden and severe
- nausea and vomiting
Minor Side Effects
Some vorapaxar side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:Less common:
- feeling sad or empty
- lack of appetite
- loss of interest or pleasure
- trouble concentrating
- trouble sleeping
For Healthcare Professionals
Applies to vorapaxar: oral tablet
Bleeding, including life-threatening and fatal bleeding, is the most commonly reported adverse reaction.[Ref]
Very common (10% or more): Bleeding
Common (1% to 10%): Anemia, iron deficiency[Ref]
Common (1% to 10%): Rashes, eruptions, exanthemas[Ref]
Common (1% to 10%): Gastrointestinal bleeding[Ref]
Common (1% to 10%): Retinopathy or retinal disorder, diplopia/oculomotor disturbances[Ref]
Uncommon (0.1% to 1%): Intracranial bleeding[Ref]
1. "Product Information. Zontivity (vorapaxar)." Merck & Company Inc, Whitehouse Station, NJ.
It is possible that some side effects of Zontivity may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about Zontivity (vorapaxar)
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- Drug Interactions
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- Drug class: protease-activated receptor-1 antagonists
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