Protease-activated receptor-1 antagonists
What are Protease-activated receptor-1 antagonists
Protease-activated receptor-1 (PAR 1) antagonists have an antiplatelet effect by inhibiting thrombin-related platelet aggregation.
Thrombin's cellular effects are mediated by PARs therefore the action of the PAR 1 antagonists alters signalling in platelets and interferes with platelet activation.
PAR 1 antagonists are used to reduce the risk of thrombotic cardiovascular events in patients who have an increased risk of myocardial infarction or peripheral arterial disease.
List of Protease-activated receptor-1 antagonists:
| Drug Name |
Reviews | Ratings |
|
|---|---|---|---|
| Zontivity (Pro, More...) generic name: vorapaxar |
0 reviews | 0.0 | |
See also...
Medical conditions associated with protease-activated receptor-1 antagonists: