Protease-activated receptor-1 antagonists
What are Protease-activated receptor-1 antagonists
Protease-activated receptor-1 (PAR 1) antagonists have an antiplatelet effect by inhibiting thrombin-related platelet aggregation.
Thrombin's cellular effects are mediated by PARs therefore the action of the PAR 1 antagonists alters signalling in platelets and interferes with platelet activation.
PAR 1 antagonists are used to reduce the risk of thrombotic cardiovascular events in patients who have an increased risk of myocardial infarction or peripheral arterial disease.
List of Protease-activated receptor-1 antagonists:
|Drug Name ( View by: Brand | Generic )||Reviews||Ratings|
|Zontivity (Pro, More...)
generic name: vorapaxar
Medical conditions associated with protease-activated receptor-1 antagonists: