Vitamin D3 Side Effects

Generic name: cholecalciferol

Medically reviewed by Drugs.com. Last updated on Aug 16, 2023.

Note: This document provides detailed information about Vitamin D3 Side Effects associated with cholecalciferol. Some dosage forms listed on this page may not apply specifically to the brand name Vitamin D3.

Applies to cholecalciferol: oral capsule, oral capsule liquid filled, oral oil, oral solution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral wafer.

Serious side effects of Vitamin D3

Along with its needed effects, cholecalciferol (the active ingredient contained in Vitamin D3) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cholecalciferol:

Incidence not known

• cough
• difficulty swallowing
• dizziness
• fast heartbeat
• hives or itching
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• skin rash
• tightness in the chest
• unusual tiredness or weakness

For healthcare professionals

Applies to cholecalciferol: compounding crystal, oral capsule, oral liquid, oral solution, oral tablet, oral tablet chewable, oral tablet disintegrating, oral wafer.

Metabolic adverse events

Metabolic side effects have included hypercalcemia.^[Ref]

Renal

• Uncommon (0.1% to 1%): Hypercalciuria^[Ref]

Dermatologic

• Rare (less than 0.1%): Pruritus, rash, urticaria^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions such as angioedema or laryngeal edema^[Ref]

Gastrointestinal

• Frequency not reported: Nausea, vomiting^[Ref]

Frequently asked questions

• Does vitamin D help with depression?

Further information

Vitamin D3 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer