Vitamin D3 Side Effects
Generic name: cholecalciferol
Medically reviewed by Drugs.com. Last updated on Mar 23, 2023.
Note: This document contains side effect information about cholecalciferol. Some dosage forms listed on this page may not apply to the brand name Vitamin D3.
Applies to cholecalciferol: oral capsule, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating, oral wafer, sublingual liquid.
Serious side effects of Vitamin D3
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high calcium levels like weakness, confusion, feeling tired, headache, upset stomach and throwing up, constipation, or bone pain.
Other side effects of Vitamin D3
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to cholecalciferol: compounding crystal, oral capsule, oral liquid, oral solution, oral tablet, oral tablet chewable, oral tablet disintegrating, oral wafer.
Metabolic side effects have included hypercalcemia.[Ref]
Uncommon (0.1% to 1%): Hypercalciuria[Ref]
Rare (less than 0.1%): Pruritus, rash, urticaria[Ref]
Frequency not reported: Hypersensitivity reactions such as angioedema or laryngeal edema[Ref]
Frequency not reported: Nausea, vomiting[Ref]
Frequently asked questions
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.