Medically reviewed on November 6, 2017
What is Replesta?
Replesta is vitamin D3. Vitamin D helps your body absorb calcium.
Replesta is used as a dietary supplement in people who do not get enough vitamin D in their diets to maintain adequate health.
Replesta may also be used for purposes not listed in this medication guide.
You should not take Replesta if you have had an allergic reaction to vitamin D, or if you have high levels of calcium or vitamin D in your body, or any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
Before taking this medicine
You should not use Replesta if you have had an allergic reaction to vitamin D, or if you have:
high levels of vitamin D in your body (hypervitaminosis D);
high levels of calcium in your blood (hypercalcemia); or
any condition that makes it hard for your body to absorb nutrients from food (malabsorption).
To make sure Replesta is safe for you, tell your doctor if you have ever had:
kidney disease; or
an electrolyte imbalance.
Certain forms of Replesta may contain ingredients you should know about, such as peanut or soybean oil, sugar, aspartame (phenylalanine), or certain food dyes. Ask a doctor before using this medicine if you have allergies, diabetes, or phenylketonuria (PKU).
Too much vitamin D could harm an unborn baby or a nursing baby. Ask a doctor before using this medicine if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.
Do not give Replesta to a child without medical advice. Your child's dose will depend on age, weight, diet, and other factors.
How should I take Replesta?
Follow all directions on your prescription label. Use only the recommended dose of Replesta. Do not use this medicine in larger or smaller amounts or for longer than recommended.
It may be best to take Replesta after a meal, but you may take this medicine with or without food.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
The chewable tablet must be chewed before you swallow it.
To take a disintegrating (Quick-Melt) tablet, place it on your tongue and do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. If desired, you may drink liquid to help swallow the dissolved tablet.
The Replesta wafer is usually taken only once per week or once per month. Follow your doctor's dosing instructions very carefully. The wafer must be chewed before you swallow it.
While using Replesta, you will need frequent blood tests. You may also need x-rays.
Your doctor will determine how long to treat you with this medicine.
Replesta may be only part of a complete program of treatment that also includes dietary changes and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.
Learn about the foods you should eat to make sure you get enough calcium and vitamin D in your diet. Your Replesta dose may need to be adjusted as you make changes to your diet.
Store at room temperature away from moisture, light, and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of vitamin D can cause serious or life-threatening side effects.
Overdose symptoms may include nausea, loss of appetite, thirst, urinating more or less than usual, body aches, stiffness, confusion, or irregular heartbeats.
What should I avoid while taking Replesta?
Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking Replesta.
Replesta side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking this medicine and call your doctor at once if you have:
chest pain, feeling short of breath;
growth problems (in a child taking Replesta); or
Less serious side effects may be more likely, and you may have none at all.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Replesta?
Certain medications can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 2 hours after you take Replesta.
Other drugs may interact with cholecalciferol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 3.01.
More about Replesta (cholecalciferol)
- Replesta Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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- Drug class: vitamins