Valchlor Side Effects
Generic name: mechlorethamine topical
Medically reviewed by Drugs.com. Last updated on Jul 6, 2022.
Note: This document contains side effect information about mechlorethamine topical. Some of the dosage forms listed on this page may not apply to the brand name Valchlor.
For the Consumer
Applies to mechlorethamine topical: topical application gel/jelly
Side effects requiring immediate medical attention
Along with its needed effects, mechlorethamine topical (the active ingredient contained in Valchlor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking mechlorethamine topical:
- Blistering, crusting, irritation, itching, or reddening of the skin
- cracked, dry, scaly skin
- pain, swelling, tenderness, or warmth on the skin
Side effects not requiring immediate medical attention
Some side effects of mechlorethamine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Darkening of the skin
For Healthcare Professionals
Applies to mechlorethamine topical: topical gel
Common (1% to 10%): Skin ulceration or blistering, skin hyperpigmentation[Ref]
Very common (10% or more): Reductions in hemoglobin, neutrophil count, or platelet count (13%)[Ref]
Common (1% to 10%): Nonmelanoma skin cancer[Ref]
More about Valchlor (mechlorethamine topical)
- Dosage information
- During pregnancy
- Pricing & coupons
- En español
- Drug class: topical antineoplastics
- FDA approval history
Related treatment guides
1. "Product Information. Valchlor (mechlorethamine topical)." Ceptaris Therapeutics (2013):
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.