Valchlor Side Effects
Generic name: mechlorethamine topical
Medically reviewed by Drugs.com. Last updated on Jul 6, 2024.
Note: This document provides detailed information about Valchlor Side Effects associated with mechlorethamine topical. Some dosage forms listed on this page may not apply specifically to the brand name Valchlor.
Applies to mechlorethamine topical: topical application gel/jelly.
Serious side effects of Valchlor
Along with its needed effects, mechlorethamine topical (the active ingredient contained in Valchlor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking mechlorethamine topical:
More common side effects
- blistering, crusting, irritation, itching, or reddening of the skin
- cracked, dry, scaly skin
- pain, swelling, tenderness, or warmth on the skin
Other side effects of Valchlor
Some side effects of mechlorethamine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common side effects
- darkening of the skin
For healthcare professionals
Applies to mechlorethamine topical: topical gel.
General adverse events
The most common adverse reactions (5% or greater) are dermatitis, pruritus, bacterial skin infection, skin ulceration or blistering, and hyperpigmentation[Ref]
Hematologic
- Very common (10% or more): Reductions in hemoglobin, neutrophil count, or platelet count (13%)[Ref]
Oncologic
Ocular
- Frequency not reported: Eye pain, burns, inflammation, photophobia, blurred vision, blindness, irreversible anterior eye injury[Ref]
Dermatologic
- Very common (10% or more): Dermatitis (56%), pruritus (20%), bacterial skin infection (11%)
- Common (1% to 10%): Skin ulceration or blistering, skin hyperpigmentation[Ref]
References
1. (2013) "Product Information. Valchlor (mechlorethamine topical)." Ceptaris Therapeutics
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Further information
Valchlor side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.