TheraCys Side Effects
Generic name: bcg
Medically reviewed by Drugs.com. Last updated on Apr 10, 2021.
Note: This document contains side effect information about bcg. Some of the dosage forms listed on this page may not apply to the brand name TheraCys.
For the Consumer
Applies to bcg: intravesical powder for suspension
Intravesical route (Powder for Suspension; Powder for Solution)
Bacillus of Calmette and Guérin (BCG) infections have been reported in health care workers and in patients because of exposure to the vaccine during preparation and administration. Serious and fatal disseminated BCG infections have occurred with intravesical administration. Manifestations of disseminated infection may not develop for months or years after therapy as BCG may persist in the urinary tract for several months after treatment. TheraCys® and TICE® BCG contain live attenuated mycobacteria and because of the potential risk for transmission, they should be prepared, handled, and disposed of as a biohazard material.
Side effects requiring immediate medical attention
Along with its needed effects, bcg (the active ingredient contained in TheraCys) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking bcg:
- Blood in urine
- fever and chills
- frequent urge to urinate
- increased frequency of urination
- joint pain
- nausea and vomiting
- painful urination (severe or continuing)
- skin rash
Side effects not requiring immediate medical attention
Some side effects of bcg may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Burning during first urination after treatment
After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, Check with your doctor immediately if you notice the following side effects:
For Healthcare Professionals
Applies to bcg: intravesical powder for reconstitution, percutaneous powder for injection
Uncommon (0.1% to 1%): Bladder constriction, pyuria, ureteric obstruction
Rare (0.01 to less than 0.1%): Epididymitis
Common (1% to 10%): Chills
Common (1% to 10%): Anemia, leukopenia
Very rare (less than 0.01%): Lymphadenopathy
Frequency not reported: Axillary or cervical lymphadenopathy, regional suppurative lymphadenitis[Ref]
Common (1% to 10%): Infection
Uncommon (0.1% to 1%): Tuberculosis infections
Very rare (less than 0.01%): Disseminated BCG infection[Ref]
Common (1% to 10%): Skin rash, sweats
Uncommon (0.1% to 1%): Rashes, eruptions and exanthema not otherwise classified
Common (1% to 10%): Pneumonitis
Rare (0.01% to 0.1%): Cough
Very rare (less than 0.01%): Renal failure acute[Ref]
Common (1% to 10%): Arthralgia, arthritis, myalgia
Common (1% to 10%): Allergic symptoms[Ref]
Uncommon (0.1% to 1%): Hepatitis, hepatic enzyme increased[Ref]
Very rare (less than 0.01%): Confusional state[Ref]
Very rare (less than 0.01%): Anorexia[Ref]
Frequency not reported: Injection site reactions: Induration, pustule formation, ulceration, caseous lesions, purulent draining, tenderness, itching, papules[Ref]
Frequently asked questions
More about TheraCys (bcg)
- Other brands
- Tice BCG
Related treatment guides
1. Cerner Multum, Inc. "Australian Product Information." O 0
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. "Product Information. Tice BCG Vaccine (BCG (BCG vaccine))." Organon, West Orange, NJ.
4. "Product Information. BCG Vaccine (BCG)." Organon Pharmaceuticals, West Orange, NJ.
Some side effects may not be reported. You may report them to the FDA.