Stendra Side Effects

Generic name: avanafil

Medically reviewed by Drugs.com. Last updated on Feb 12, 2024.

Note: This document provides detailed information about Stendra Side Effects associated with avanafil. Some dosage forms listed on this page may not apply specifically to the brand name Stendra.

Applies to avanafil: oral tablet.

Common side effects of Stendra

Some side effects of avanafil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• feeling of warmth
• fever
• muscle aches
• redness of the face, neck, arms, and occasionally, upper chest
• sore throat
• stuffy or runny nose

Less common side effects

• acid or sour stomach
• belching
• body aches or pain
• change in color vision
• chills
• cough
• cough producing mucus
• diarrhea
• difficulty having a bowel movement (stool)
• difficulty with moving
• ear congestion
• heartburn
• indigestion
• joint pain
• loss of appetite
• loss of voice
• muscle pain or stiffness
• pain or tenderness around the eyes and cheekbones
• rash
• shivering
• sneezing
• sweating
• trouble sleeping

Rare side effects

• anxiety
• bloody nose
• bone pain
• burning feeling in the chest or stomach
• confusion
• cool, pale skin
• depression
• feeling of constant movement of self or surroundings
• increased hunger
• itching skin
• muscle aching or cramping
• muscle spasms
• nightmares
• seizures
• sensation of spinning
• shakiness
• sleepiness or unusual drowsiness
• slurred speech
• swollen joints
• tenderness in the stomach area

Serious side effects of Stendra

Along with its needed effects, avanafil (the active ingredient contained in Stendra) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking avanafil:

Less common side effects

• blurred vision
• dizziness
• headache
• nervousness
• pounding in the ears
• slow or fast heartbeat

Rare side effects

• arm, back, or jaw pain
• bladder pain
• bloating or swelling of the face, arms, hands, lower legs, or feet
• bloody or cloudy urine
• chest pain, discomfort, or tightness
• chest tightness or heaviness
• difficult or labored breathing
• difficult, burning, or painful urination
• fast, irregular, pounding, or racing heartbeat or pulse
• frequent urge to urinate
• increased erection
• lower back or side pain
• nausea and vomiting
• pain in the groin or genitals
• pain, redness, or swelling in the arm or leg
• rapid weight gain
• sharp back pain just below the ribs
• sweating
• tingling of the hands or feet
• unusual tiredness or weakness
• unusual weight gain or loss

Incidence not known

• pain or discomfort in the arms, jaw, back, or neck
• seeing flashes or sparks of light
• seeing floating spots before the eyes, veil, or curtain appearing across part of vision
• sudden decrease or loss of hearing

For healthcare professionals

Applies to avanafil: oral tablet.

General adverse events

The most common side effects reported were headache, flushing, nasal and sinus congestion and back pain.^[Ref]

Cardiovascular

• Very common (10% or more): Flushing (up to 10.1%)
• Common (1% to 10%): Hypertension, abnormal electrocardiogram
• Uncommon (0.1% to 1%): Peripheral edema, angina, unstable angina, deep vein thrombosis, palpitations, hot flush, increased heart rate
• Rare (less than 0.1%): Tachycardia, chest pain, increased blood pressure, cardiac murmur
• Postmarketing reports: Hypotension^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Balanitis, increased erection
• Rare (less than 0.1%): Penis disorder, spontaneous penile erection, genital pruritus, increased prostate specific antigen
• Postmarketing reports: Priapism, hematuria, hematospermia, penile hemorrhage^[Ref]

Dermatologic

• Common (1% to 10%): Rash
• Uncommon (0.1% to 1%): Pruritus^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, dyspepsia, nausea, constipation
• Uncommon (0.1% to 1%): Gastritis, gastroesophageal reflux disease, stomach discomfort, vomiting, dyspepsia, nausea
• Rare (less than 0.1%): Dry mouth, lower abdominal pain^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain, arthralgia
• Uncommon (0.1% to 1%): Muscle spasms, musculoskeletal pain, myalgia, pain in extremity, muscle tightness
• Rare (less than 0.1%): Flank pain^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 12.1%)
• Common (1% to 10%): Dizziness
• Uncommon (0.1% to 1%): Somnolence, vertigo, sinus headache
• Rare (less than 0.1%): Psychomotor hyperactivity^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Depression, insomnia
• Rare (less than 0.1%): Premature ejaculation, inappropriate affect^[Ref]

Renal

• Uncommon (0.1% to 1%): Hematuria, nephrolithiasis, pollakiuria, urinary tract infection
• Rare (less than 0.1%): Blood urine present^[Ref]

Respiratory

• Common (1% to 10%): Nasal congestion, nasopharyngitis, upper respiratory infection (URI), bronchitis, sinusitis, sinus congestion
• Uncommon (0.1% to 1%): Oropharyngeal pain, cough, exertional dyspnea, wheezing
• Rare (less than 0.1%): Rhinorrhea, upper respiratory tract congestion^[Ref]

Hematologic

• Uncommon (0.1% to 1%): Epistaxis^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Increased alanine aminotransferase
• Rare (less than 0.1%): Increased blood bilirubin^[Ref]

Immunologic

• Common (1% to 10%): Influenza
• Rare (less than 0.1%): Seasonal allergy^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Hypoglycemia, increased blood glucose
• Rare (less than 0.1%): Gout, Increased weight^[Ref]

Ocular

• Uncommon (0.1% to 1%): Blurred vision, vision loss
• Postmarketing reports: Non-arteritic anterior ischemic optic neuropathy (NAION)^[Ref]

Other

• Uncommon (0.1% to 1%): Fatigue, tinnitus
• Rare (less than 0.1%): Asthenia, influenza-like illness, increased body temperature
• Postmarketing reports: Loss of hearing^[Ref]

Further information

Stendra side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer