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Seromycin Side Effects

Generic name: cycloserine

Medically reviewed by Drugs.com. Last updated on Nov 3, 2020.

Note: This document contains side effect information about cycloserine. Some of the dosage forms listed on this page may not apply to the brand name Seromycin.

For the Consumer

Applies to cycloserine: oral capsule

Side effects requiring immediate medical attention

Along with its needed effects, cycloserine (the active ingredient contained in Seromycin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cycloserine:

More common

Less common

Side effects not requiring immediate medical attention

Some side effects of cycloserine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to cycloserine: oral capsule

General

The most commonly reported side effects included hypersensitivity and nervous system manifestations.[Ref]

Nervous system

Character changes, coma, convulsions, drowsiness, headache, hyperreflexia, major and minor (localized) clonic seizures, memory loss, paresis, paresthesia, somnolence, tremor, vertigo appeared to be dose related.[Ref]

Frequency not reported: Central nervous system toxicity, character changes, coma, convulsions, drowsiness, headache, hyperreflexia, major and minor (localized) clonic seizures, memory loss, paresis, paresthesia, somnolence, tremor, vertigo[Ref]

Psychiatric

Frequency not reported: Aggression, anxiety, confusion, disorientation, dysarthria, hyperirritability, psychosis with/without suicidal tendencies[Ref]

Aggression, confusion, disorientation, dysarthria, hyperirritability, and psychosis with/without suicidal tendencies appeared to be dose related.[Ref]

Hypersensitivity

Frequency not reported: Allergic dermatitis, allergy, drug hypersensitivity[Ref]

Hematologic

Frequency not reported: Megaloblastic anemia, sideroblastic anemia[Ref]

Metabolic

Frequency not reported: Folic acid deficiency, vitamin B12 deficiency[Ref]

Dermatologic

Frequency not reported: Rash/skin rash[Ref]

Cardiovascular

Sudden onset of congestive heart failure occurred in patients given 1000 to 1500 mg/day.[Ref]

Frequency not reported: Congestive heart failure[Ref]

Hepatic

Frequency not reported: Elevated serum transaminases[Ref]

Elevated serum transaminases occurred in patients with preexisting liver disease.[Ref]

References

1. "Product Information. Seromycin (cycloserine)." Dura Pharmaceuticals, San Diego, CA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.