Skip to Content
Vaccines aren’t just for kids. Is your teen protected?

Cycloserine Pregnancy and Breastfeeding Warnings

Cycloserine is also known as: Seromycin, Seromycin Pulvules

Cycloserine Pregnancy Warnings

Cycloserine has been assigned to pregnancy category C by the FDA. Animal studies with high doses have not revealed evidence of teratogenicity. Cycloserine crosses the placenta and may achieve fetal blood levels similar to those in maternal blood. The Collaborative Perinatal Project found no adverse effects in 3 mother-child pairs who were exposed to cycloserine during the first trimester. Cycloserine is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

See references

Cycloserine Breastfeeding Warnings

Cycloserine is excreted into human milk in concentrations that may approach maternal serum levels. Cycloserine is considered compatible with breast-feeding by the American Academy of Pediatrics. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

See references

References for pregnancy information

  1. American Thoracic Society, CDC, Infectious Diseases Society of America "Treatment of tuberculosis." MMWR Morb Mortal Wkly Rep 52(RR-11) (2003): 1-77
  2. "Product Information. Seromycin (cycloserine)." Dura Pharmaceuticals, San Diego, CA.
  3. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):

References for breastfeeding information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):
  2. "Product Information. Seromycin (cycloserine)." Dura Pharmaceuticals, San Diego, CA.
  3. "American Academy of Pediatrics. Committee on Drugs. The transfer of drugs and other chemicals into human milk." Pediatrics 108 (2001): 776-89

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide