Skip to Content

Cycloserine Pregnancy and Breastfeeding Warnings

Cycloserine is also known as: Seromycin, Seromycin Pulvules

Medically reviewed on Dec 15, 2017

Cycloserine Pregnancy Warnings

Cycloserine has been assigned to pregnancy category C by the FDA. Animal studies with high doses have not revealed evidence of teratogenicity. Cycloserine crosses the placenta and may achieve fetal blood levels similar to those in maternal blood. The Collaborative Perinatal Project found no adverse effects in 3 mother-child pairs who were exposed to cycloserine during the first trimester. Cycloserine is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

See references

Cycloserine Breastfeeding Warnings

Cycloserine is excreted into human milk in concentrations that may approach maternal serum levels. Cycloserine is considered compatible with breast-feeding by the American Academy of Pediatrics. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

See references

References for pregnancy information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):
  2. American Thoracic Society, CDC, Infectious Diseases Society of America "Treatment of tuberculosis." MMWR Morb Mortal Wkly Rep 52(RR-11) (2003): 1-77
  3. "Product Information. Seromycin (cycloserine)." Dura Pharmaceuticals, San Diego, CA.

References for breastfeeding information

  1. "Product Information. Seromycin (cycloserine)." Dura Pharmaceuticals, San Diego, CA.
  2. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 6th ed." Philadelphia, PA: Lippincott Williams & Wilkins (2002):
  3. "American Academy of Pediatrics. Committee on Drugs. The transfer of drugs and other chemicals into human milk." Pediatrics 108 (2001): 776-89

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide