Sensipar Side Effects
Generic name: cinacalcet
Medically reviewed by Drugs.com. Last updated on Aug 18, 2023.
Note: This document contains side effect information about cinacalcet. Some dosage forms listed on this page may not apply to the brand name Sensipar.
Summary
Common side effects of Sensipar include: decreased plasma testosterone, diarrhea, dizziness, myalgia, nausea, vomiting, and hypoparathyroidism. Other side effects include: dialysis access infection, asthenia, chest pain, hypertension, hypotension, and anorexia. Continue reading for a comprehensive list of adverse effects.
Applies to cinacalcet: oral tablets.
Side effects include:
Dialysis patients with secondary hyperparathyroidism: Nausea, vomiting, diarrhea, myalgia, dyspnea, cough, hypotension, headache, hypocalcemia, muscle spasms, abdominal pain (including upper abdominal pain), dizziness, hyperkalemia, upper respiratory tract infection, dyspepsia, hypertension, asthenia, anorexia/decreased appetite, noncardiac chest pain, access infection, constipation.
Patients with hypercalcemia associated with parathyroid carcinoma or primary hyperparathyroidism: Adverse effects generally similar to those observed in dialysis patients.
For Healthcare Professionals
Applies to cinacalcet: oral tablet.
Cardiovascular
Very common (10% or more): Hypotension (11.6%)
Common (1% to 10%): Hypertension
Frequency not reported: Worsening heart failure, QT prolongation and ventricular arrhythmia secondary to hypocalcemia[Ref]
Gastrointestinal
Very common (10% or more): Nausea (31%), vomiting (27%), diarrhea (21%), dyspepsia (13%), abdominal pain (10.9%)
Common (1% to 10%): Upper abdominal pain, dyspepsia, anorexia, constipation[Ref]
Hypersensitivity
Common (1% to 10%): Hypersensitivity reactions
Postmarketing reports: Rash, angioedema, urticaria[Ref]
Local
Common (1% to 10%): Access site infection[Ref]
Dermatologic
Very common (10% or more): Paresthesia (14 to 29%)
Very rare (less than 0.01%): Leukocytoclastic vasculitis with palpable purpura on both upper and lower extremities[Ref]
Hematologic
Common (1% to 10%): Anemia[Ref]
Metabolic
Very common (10% or more): Hypocalcemia (11.2%)
Common (1% to 10%): Hyperkalemia, dehydration[Ref]
Respiratory
Very common (10% or more): Cough (11.7%), upper respiratory infection (11%)
Common (1% to 10%): Dyspnea[Ref]
Endocrine
Common (1% to 10%): Reduced testosterone levels[Ref]
Musculoskeletal
Very common (10% or more): Myalgia (15%), muscle spasms (11%)
Common (1% to 10%): Limb pain, back pain, fracture, arthralgia, noncardiac chest pain[Ref]
Nervous system
Very common (10% or more): Paresthesia (up to 29%), headache (11.5%), dizziness (10%)
Common (1% to 10%): Fatigue, seizures[Ref]
Other
Common (1% to 10%): Asthenia[Ref]
Renal
Common (1% to 10%): Dialysis access site infection[Ref]
More about Sensipar (cinacalcet)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (9)
- Drug images
- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: calcimimetics
- Breastfeeding
- En español
Patient resources
Professional resources
Related treatment guides
References
1. Product Information. Sensipar (cinacalcet). Amgen USA. 2004.
2. Cerner Multum, Inc. UK Summary of Product Characteristics.
3. Cerner Multum, Inc. Australian Product Information.
4. Giannikopoulos G, Zorzou MP, Stamoulis I, et al. Cinacalcet-induced leukocytoclastic vasculitis. Am J Kidney Dis. 2009;54:e5-e8.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.