Sensipar Side Effects

Generic name: cinacalcet

Medically reviewed by Drugs.com. Last updated on Aug 18, 2023.

Note: This document contains side effect information about cinacalcet. Some dosage forms listed on this page may not apply to the brand name Sensipar.

Summary

Common side effects of Sensipar include: decreased plasma testosterone, diarrhea, dizziness, myalgia, nausea, vomiting, and hypoparathyroidism. Other side effects include: dialysis access infection, asthenia, chest pain, hypertension, hypotension, and anorexia. Continue reading for a comprehensive list of adverse effects.

Applies to cinacalcet: oral tablets.

Side effects include:

Dialysis patients with secondary hyperparathyroidism: Nausea, vomiting, diarrhea, myalgia, dyspnea, cough, hypotension, headache, hypocalcemia, muscle spasms, abdominal pain (including upper abdominal pain), dizziness, hyperkalemia, upper respiratory tract infection, dyspepsia, hypertension, asthenia, anorexia/decreased appetite, noncardiac chest pain, access infection, constipation.

Patients with hypercalcemia associated with parathyroid carcinoma or primary hyperparathyroidism: Adverse effects generally similar to those observed in dialysis patients.

For Healthcare Professionals

Applies to cinacalcet: oral tablet.

Cardiovascular

Very common (10% or more): Hypotension (11.6%)

Common (1% to 10%): Hypertension

Frequency not reported: Worsening heart failure, QT prolongation and ventricular arrhythmia secondary to hypocalcemia^[Ref]

Gastrointestinal

Very common (10% or more): Nausea (31%), vomiting (27%), diarrhea (21%), dyspepsia (13%), abdominal pain (10.9%)

Common (1% to 10%): Upper abdominal pain, dyspepsia, anorexia, constipation^[Ref]

Hypersensitivity

Common (1% to 10%): Hypersensitivity reactions

Postmarketing reports: Rash, angioedema, urticaria^[Ref]

Local

Common (1% to 10%): Access site infection^[Ref]

Dermatologic

Very common (10% or more): Paresthesia (14 to 29%)

Very rare (less than 0.01%): Leukocytoclastic vasculitis with palpable purpura on both upper and lower extremities^[Ref]

Hematologic

Common (1% to 10%): Anemia^[Ref]

Metabolic

Very common (10% or more): Hypocalcemia (11.2%)

Common (1% to 10%): Hyperkalemia, dehydration^[Ref]

Respiratory

Very common (10% or more): Cough (11.7%), upper respiratory infection (11%)

Common (1% to 10%): Dyspnea^[Ref]

Endocrine

Common (1% to 10%): Reduced testosterone levels^[Ref]

Musculoskeletal

Very common (10% or more): Myalgia (15%), muscle spasms (11%)

Common (1% to 10%): Limb pain, back pain, fracture, arthralgia, noncardiac chest pain^[Ref]

Nervous system

Very common (10% or more): Paresthesia (up to 29%), headache (11.5%), dizziness (10%)

Common (1% to 10%): Fatigue, seizures^[Ref]

Other

Common (1% to 10%): Asthenia^[Ref]

Renal

Common (1% to 10%): Dialysis access site infection^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer