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Rapaflo Side Effects

Generic Name: silodosin

Note: This document contains side effect information about silodosin. Some of the dosage forms listed on this page may not apply to the brand name Rapaflo.

In Summary

Common side effects of Rapaflo include: retrograde ejaculation. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to silodosin: oral capsule

Along with its needed effects, silodosin (the active ingredient contained in Rapaflo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking silodosin:

Less common
  • Chills
  • cold sweats
  • confusion
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
Incidence not known
  • Abdominal or stomach pain
  • clay-colored stools
  • dark urine
  • fever
  • headache
  • itching
  • loss of appetite
  • nausea
  • pinpoint red or purple spots on the skin
  • rash
  • skin blisters
  • unpleasant breath odor
  • unusual tiredness or weakness
  • vomiting of blood
  • yellow eyes or skin

Some side effects of silodosin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Change or problem with discharge of semen
Less common
  • Diarrhea
  • muscle aches
  • sore throat
  • stuffy or runny nose

For Healthcare Professionals

Applies to silodosin: oral capsule

General

The most common adverse reaction was retrograde ejaculation.[Ref]

Genitourinary

Very common (10% or more): Retrograde ejaculation (28.1%)
Common (1% to 10%): Prostate-specific antigen (PSA) increased
Uncommon (0.1% to 1%): Priapism[Ref]

Respiratory

Common (1% to 10%): Nasopharyngitis, nasal congestion, sinusitis, rhinorrhea
Postmarketing reports: Pharyngeal edema[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache
Uncommon (0.1% to 1%): Syncope[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, abdominal pain
Postmarketing reports: Swollen tongue[Ref]

Cardiovascular

Common (1% to 10%): Orthostatic hypotension[Ref]

Other

Common (1% to 10%): Asthenia[Ref]

Psychiatric

Common (1% to 10%): Insomnia[Ref]

Ocular

Frequency not reported: Intraoperative floppy iris syndrome[Ref]

Dermatologic

Postmarketing reports: Toxic skin eruption, purpura, skin rash, pruritus, urticaria[Ref]

Hepatic

Postmarketing reports: Jaundice, hepatic function impaired, transaminases increased[Ref]

Immunologic

Postmarketing reports: Allergic-type reactions[Ref]

References

1. "Product Information. Rapaflo (silodosin)." Watson Pharmaceuticals, Corona, CA.

Some side effects of Rapaflo may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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