Skip to main content

Pegvisomant Side Effects

Medically reviewed by Last updated on Nov 9, 2023.

Applies to pegvisomant: subcutaneous powder for solution.

Serious side effects of Pegvisomant

Along with its needed effects, pegvisomant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking pegvisomant:

More common

Less common

Incidence not known

Other side effects of Pegvisomant

Some side effects of pegvisomant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to pegvisomant: subcutaneous powder for injection.


Frequency not reported: Liver test elevations[Ref]


Frequency not reported: Hypoglycemia in patients with diabetes mellitus[Ref]


Frequency not reported: Lipohypertrophy[Ref]


Frequency not reported: Cross-reactivity with growth hormone assay[Ref]


Frequency not reported: Systemic hypersensitivity[Ref]


1. Product Information. Somavert (pegvisomant). Pharmacia and Upjohn. 2003.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.