Oxymetazoline Topical Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 10, 2023.

Applies to oxymetazoline topical: topical application cream.

Serious side effects

Along with its needed effects, oxymetazoline topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking oxymetazoline topical:

Less common side effects

• blistering, crusting, irritation, itching, or reddening of the skin
• cracked, dry, scaly skin
• swelling or pain at the application site
• worsening of rosacea pimples

For healthcare professionals

Applies to oxymetazoline topical: topical cream.

Local adverse events

• Common (1% to 10%): Application site dermatitis/pruritus/pain
• Uncommon (0.1% to 1%): Application site erythema^[Ref]

Dermatologic

• Common (1% to 10%): Worsening inflammatory lesions of rosacea^[Ref]

Further information

Oxymetazoline topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer