Oxilan Side Effects

Generic name: ioxilan

Note: This document contains side effect information about ioxilan. Some dosage forms listed on this page may not apply to the brand name Oxilan.

Applies to ioxilan: injectable solution.

General

General side effects including headache (3.6%), fever (1.7%), chills (0.6%), asthenia, chest and back pain, edema of the neck, facial edema, pain, and peripheral edema have been reported.^[Ref]

Cardiovascular

Common (1% to 10%): Angina pectoris (1.3%), hypertension (1.1%)

Uncommon (0.1% to 1%): Bradycardia, hypotension, atrial fibrillation, syncope, tachycardia, vasodilation, ventricular extrasystole^[Ref]

Severe life-threatening cardiovascular reactions and fatalities have occurred. Most deaths occur during injection or 5 to 10 minutes later; the main feature being cardiac arrest with cardiovascular disease as the main aggravating factor.^[Ref]

Gastrointestinal

Common (1% to 10%): Nausea (1.5%)

Uncommon (0.1% to 1%): Diarrhea, nausea with vomiting, constipation, dyspepsia, dysphagia, gastrointestinal hemorrhage, ileus^[Ref]

Nervous system

Common (1% to 10%): Headache (3.6%)

Uncommon (0.1% to 1%): Dizziness, hypotonia, nystagmus, paresthesia, somnolence, vertigo, taste perversion^[Ref]

Other

Common (1% to 10%): Fever (1.7%)

Uncommon (0.1% to 1%): Chills, asthenia, edema of the neck, facial edema, pain, peripheral edema^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Urticaria, rash, pruritus, sweating^[Ref]

Endocrine

Uncommon (0.1% to 1%): Hypothyroidism or transient thyroid suppression^[Ref]

Genitourinary

Uncommon (0.1% to 1%): Anuria, dysuria, hematuria, urinary tract infection, urination impairment^[Ref]

Hepatic

Uncommon (0.1% to 1%): Liver failure^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Allergic reaction^[Ref]

The reported incidence of adverse reactions to contrast agents in patients with a history of allergy is twice that of the general population. Patients with a history of previous reactions to a contrast agent are three times more susceptible than other patients. However, sensitivity to contrast agents does not appear to increase with repeated examinations.^[Ref]